- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02886247
Pancreatic Cancer Registry: For Any Person With a Personal or Family History (NFPTR)
July 26, 2023 updated by: Johns Hopkins University
National Familial Pancreas Tumor Registry
The NFPTR was established in 1994 to find the causes of pancreatic cancer.
In brief, the investigators are interested in both the genetic and non-genetic causes of pancreatic cancer.
The investigators are particularly interested in finding the genes that cause pancreatic cancer to cluster in some families.
Up to 10% of pancreatic cancer patients have another close relative who has also developed pancreatic cancer.
This clustering of pancreatic cancers in families has yet to be explained; however, the investigators continue to identify new familial pancreatic cancer genes that explain this clustering in subsets of families.
For example, in 2009 and 2012 the investigators discovered that mutations in the PALB2 and ATM genes jointly account up to 5% of the clustering of pancreatic cancer in families.
Study Overview
Status
Recruiting
Study Type
Observational
Enrollment (Estimated)
12000
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Alison Klein, PhD, MHS
- Phone Number: 410-955-3502
- Email: pancreas@jhmi.edu
Study Locations
-
-
Maryland
-
Baltimore, Maryland, United States, 21231
- Recruiting
- Johns Hopkins Hospital
-
Contact:
- Alison Klein, PhD, MHS
- Phone Number: 410-955-3511
- Email: aklein1@jhmi.edu
-
Contact:
- Email: pancreas@jhmi.edu
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Sampling Method
Non-Probability Sample
Study Population
individuals with a personal or family history of pancreas tumors
Description
Inclusion Criteria:
- personal or family history of pancreas tumors
Exclusion Criteria:
- none
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Observational Models: Family-Based
- Time Perspectives: Prospective
Cohorts and Interventions
Group / Cohort |
---|
participants
individuals with a personal or family history of pancreas tumors
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
pancreatic cancer
Time Frame: 35 years
|
35 years
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Principal Investigator: Alison Klein, PhD, MHS, Johns Hopkins University
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
June 1, 1994
Primary Completion (Estimated)
June 1, 2030
Study Completion (Estimated)
December 1, 2032
Study Registration Dates
First Submitted
August 29, 2016
First Submitted That Met QC Criteria
August 31, 2016
First Posted (Estimated)
September 1, 2016
Study Record Updates
Last Update Posted (Actual)
July 28, 2023
Last Update Submitted That Met QC Criteria
July 26, 2023
Last Verified
July 1, 2023
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- NA_00035453
- P50CA062924 (U.S. NIH Grant/Contract)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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