The Blood Pressure Analysis on Critically Ill Patients

The study is to explore the relationship between coefficient of variation of harmonic magnitude (HCV) and different organ failures among those critically ill patients. In the future, we can act as a warning system on patients with multiple organ failures or terminal illness, also as an indicator of treatment effect.

Study Overview

• Status: Unknown
• Conditions: Multiple Organ Failure; Intensive Care Unit Syndrome
• Intervention / Treatment: Diagnostic test: ICU patient

• Study Type: Observational
• Enrollment (Anticipated): 100

Contacts and Locations

• Study Contact: Name: Tzu-Yi Chuang; Phone Number: 3787 886-3-3699721; Email: revival_chuang@yahoo.com

Study Locations

• Taiwan
  • Taoyuan, Taiwan, 33004
    • Recruiting
    • Taoyuan General Hospital, Ministry of Health and Welfare

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 20 years to 99 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Patients without severe arrhythmia admitted to the ICU of Taoyuan General Hospital.

Description

Inclusion Criteria:

• ICU patients in the 20-to-99 age range
• Subjects agree to sign the Informed Consent Form and are willing to cooperate with Arterial pulse measurement

Exclusion Criteria:

• Subject has severe arrhythmia

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
ICU patient; Pulse pressure of the radical artery was obtained by arterial line. The output of the transducer was connected to an IBM PC for analysis via an A/D converter with sampling rate = 250 datapoints/sec. The pulse spectrum was analyzed with the Fourier transformation using T (period) = 1 pulse time.	Diagnostic test: ICU patient; Our study is to measure the coefficient of variation of the HCV of the radial arterial pulse among ICU patients with multiple organ failures (MOF). Patients admitted to Taoyuan General Hospital were recorded during the 6 months study.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Coefficient of variation of harmonic magnitude	We measure the blood pressure of participants with multiple organ failures (MOF) by pressure transducer during the 6 months study in the ICU of Taoyuan General Hospital. The radial artery pressure pulse of both hands are recorded with a pressure transducer fixed on the skin with tape and an adjustable belt with a small button to achieve suitable pressure.	15 min

Collaborators and Investigators

• Sponsor: Taoyuan General Hospital
• Investigators: Principal Investigator: Tzu-Yi Chuang, Taoyuan General Hospital, Minstry of Healthy and Welfare

Study record dates

Study Major Dates

• Study Start (Actual): April 30, 2019
• Primary Completion (Anticipated): December 1, 2020
• Study Completion (Anticipated): December 1, 2020

Study Registration Dates

• First Submitted: January 30, 2019
• First Submitted That Met QC Criteria: January 31, 2019
• First Posted (Actual): February 1, 2019

Study Record Updates

• Last Update Posted (Actual): March 27, 2020
• Last Update Submitted That Met QC Criteria: March 26, 2020
• Last Verified: March 1, 2020

More Information

Terms related to this study

• Keywords: Blood pressure; Arterial pulse; Coefficient of variation of harmonic magnitude
• Additional Relevant MeSH Terms: Pathologic Processes; Shock; Multiple Organ Failure
• Other Study ID Numbers: TYGH107041

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No