Effects of ABO Blood Types on the Survival and Marginal Bone Resorption of Dental Implants

This study evaluates implant survival and marginal bone resorption in patients receiving implant treatment with respect to demographic data and AB0 (groups) blood types.

Study Overview

• Status: Completed
• Conditions: Implant Tissue Failure

Detailed Description

For a successful dental implant, optimal soft and hard tissue characteristics are required. These characteristics include appropriate bone quality and a healthy adherent keratinized gingiva that surrounds the implant neck. The most common complications are peri-implant diseases and marginal bone loss for dental implants. Marginal bone loss around the implant may be observed as a long-term complication due to microbial dental plaque-induced peri-implant inflammatory disease or may be observed in the absence of such a disease.

The immune system and genetic factors are known to have important effects on implant success, and ABO blood types are also included in the genetic factors. In the studies evaluating the association of ABO blood types with increased susceptibility to infection and various systemic diseases, it was reported that the percentages of blood types differed significantly, especially in skeletal-muscle system injuries, fractures and cardiovascular disease susceptibility. Also some researchers reported that blood types may be effective on the bacteria colonization which is the main reason of the periodontal diseases. ABO blood types may have an impact on dental implant success and survival.

• Study Type: Observational
• Enrollment (Actual): 963

Contacts and Locations

Study Locations

• Turkey
  • Van, Turkey, 65100
    • Serap Keskin Tunc

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 19 years to 78 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

This cross-sectional study was performed on patients who had undergone implant treatment and had prosthetic rehabilitation at the Faculty of Dentistry of the Van Yuzuncu Yil University between 2010 and 2017 and who had been followed up for at least one year.

Description

Inclusion Criteria:

• The inclusion criteria for the study group included being 18 years of age and non-smoker, not having any systemic disease, not having undergone any hard and soft tissue augmentation during implant surgery, having implants placed at bone level, having received cylindrical form implants with SLA surface structure, not missing any follow-up visits after implant surgery evidenced with radiographic recordings, having received flat abutment, having cemented implants, and being rehabilitated with fixed prosthetic restoration.

Exclusion Criteria:

• No

Study Plan

How is the study designed?

Design Details

• Observational Models: Other
• Time Perspectives: Cross-Sectional

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Marginal bone resorption measurements (mm) in dental implants.	We evaluated marginal bone resorption in patients receiving implant treatment with respect to ABO blood types. These measurements will be measured by periapical radiographs. Periapical radiographs were taken with a parallel technique to measure the amount of mesial and distal bone resorption in the neck region of the implants.	1 year
Implant survival rates according to demographic data	We evaluated implant survival rates by age and sex on a yearly basis	1 year

Collaborators and Investigators

• Sponsor: Yuzuncu Yıl University

Study record dates

Study Major Dates

• Study Start (Actual): December 15, 2017
• Primary Completion (Actual): December 15, 2018
• Study Completion (Actual): December 15, 2018

Study Registration Dates

• First Submitted: August 6, 2019
• First Submitted That Met QC Criteria: August 8, 2019
• First Posted (Actual): August 13, 2019

Study Record Updates

• Last Update Posted (Actual): August 13, 2019
• Last Update Submitted That Met QC Criteria: August 8, 2019
• Last Verified: August 1, 2019

More Information

Terms related to this study

• Keywords: Blood types, Dental implant, Marginal Bone Resorption, Implant Survival
• Additional Relevant MeSH Terms: Musculoskeletal Diseases; Bone Diseases; Bone Resorption
• Other Study ID Numbers: 29112017/05

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No