Epidemiology and Determinants of Short-Term Outcome in Critically Ill Patients With Near-Hanging Injury (ANTIGONE)

Outcome After Near-Hanging Injury

Near-Hanging is a catastrophic event that has been merely studied in the literature. We aimed to report the outcomes, and early predictors of hospital survivors in critically ill patients with near-hanging.

Patients admitted to 31 university or university-affiliated participating ICUs in France and Belgium between 1992 and 2014 were studied retrospectively. Hospital survival was the main judgment criterion.

Study Overview

• Status: Completed
• Conditions: Near Hanging
• Intervention / Treatment: Other: logistic regression

• Study Type: Observational
• Enrollment (Actual): 900

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: N/A

• Sampling Method: Non-Probability Sample

Study Population

All eligible cases extracted from the participation ICUs hospital registries were included in the present study if they were older than 18 years, with in- or out-of-hospital near-hanging self-arm, and if they required ICU management.

Description

Inclusion Criteria:

• any of the following code corresponding in the International Statistical Classification of Diseases and Related Health Problems, 10th Revision: Intentional self-harm by hanging, strangulation and suffocation (X70). Local investigators reviewed the medical records of the patients thus identified to select adults admitted to the ICU after successfully resuscitated near-hanging injury.
• older than 18 years
• requiring ICU management

Exclusion Criteria:

-

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Hospital survival	Other: logistic regression; To identify associations between factors listed in Table 1 and hospital survival, we used logistic regression
No hospital survival	Other: logistic regression; To identify associations between factors listed in Table 1 and hospital survival, we used logistic regression

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Hospital survival	Survival rate at hospital discharge	1 year

Collaborators and Investigators

• Sponsor: Versailles Hospital

Publications and helpful links

General Publications

• de Charentenay L, Schnell G, Pichon N, Schenck M, Cronier P, Perbet S, Lascarrou JB, Rossignol T, Lesieur O, Argaud L, Colin G, Cholley B, Quenot JP, Merdji H, Silva S, Piagnerelli M, Chelly J, Salvetti M, Couraud S, Deye N, Danguy des Deserts M, Paul M, Thiery G, Simon M, Martin C, Vincent F, Das V, Jacq G, Jacobs F, Soummer A, Mayaux J, Beuret P, Ouchenir A, Durant C, Darmon M, Azoulay E, Sauneuf B, Daubin C, Mongardon N, Biard L, Cariou A, Geeraerts T, Legriel S; Antigone Investigators. Outcomes in 886 Critically Ill Patients After Near-Hanging Injury. Chest. 2020 Dec;158(6):2404-2413. doi: 10.1016/j.chest.2020.07.064. Epub 2020 Aug 3.

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 1992
• Primary Completion (Actual): May 1, 2014
• Study Completion (Actual): June 1, 2014

Study Registration Dates

• First Submitted: September 17, 2019
• First Submitted That Met QC Criteria: September 18, 2019
• First Posted (Actual): September 20, 2019

Study Record Updates

• Last Update Posted (Actual): September 20, 2019
• Last Update Submitted That Met QC Criteria: September 18, 2019
• Last Verified: September 1, 2019

More Information

Terms related to this study

• Other Study ID Numbers: P12/17_Antigone

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No