- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04444947
Influencing Factors in Patients With Colorectal and Gastric Polyps a Retrospective Study
Influencing Factors in Patients With Colorectal and Gastric a Retrospective Study
Study Overview
Status
Conditions
Detailed Description
Colorectal cancer (CRC) is the third most common cancer in the world. what's more, CRC is therefore an important public health concern in China due to its rising incidence and prevalence, in addition to the burden of disease. There is robust evidence indicating that early detection by screening and removal of cancer precursor lesions offers an effective method of reducing colorectal cancer morbidity and mortality. Studies have shown that colorectal polyps are considered to be related to colorectal cancer, especially adenoma .The primary aim of this study was to identify high risk features of multiple polyps based on size, location and histological type. Patient age and gender were also characterized on the basis of a contingency analysis of a large series of Chinese patients with colorectal polyps. These data provide important information on risk factors associated with multiple polyps, which will serve as evidence for an individualized approach to colonoscopy screening guidelines in China.
Similarly, recent years, with the widespread use of gastroscopy, people's health awareness and lifestyle changes, more and more people have performed gastroscopy, so a large number of patients with gastric polyps can be found in the clinic. Gastric polyps are raised lesions that originate in the mucosal layer or submucosa and protrude into the stomach cavity. According to their pathological characteristics, they can be divided into two categories: mucosal layer and non-mucosal layer.Gastric polyps originating from mucosal layers, represented by natural, fundus glandular and adenomatous polyps, are the most common in clinical practice, while non-mucosal polyps including gastric stromal tumors and inflammatory fibrous polyps are more common in clinical practice. Although the incidence of gastric polyps is far less than that of intestinal polyps, some pathological types, especially adenomatous polyps, have obvious malignant potential and are recognized as precancerous lesions .
Therefore, we retrospectively analyzed the records of patients with gastrointestinal polyps in our hospital in the past years, and provided epidemiological data to study the factors in polyps.
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
-
-
Jiangsu
-
Nanjing, Jiangsu, China
- Jiangsu Provincial People's Hospital
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- patients who underwent colonoscopies
Exclusion Criteria:
- (1) Patients with Crohn's disease, inflammatory bowel disease, and colorectal cancer; (2) Patients with ulcerative bowel disease, and intestinal tuberculosis; (3) Patients with history of familial polyposis; (4) All patients without complete endoscopic reports and complete demographics records.
Study Plan
How is the study designed?
Design Details
- Observational Models: Case-Control
- Time Perspectives: Other
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Influencing factors in patients with colorectal polyps: a retrospective study
Time Frame: JUNE 30,2020
|
risk factors
|
JUNE 30,2020
|
Collaborators and Investigators
Investigators
- Principal Investigator: yue WANG, master, the Human Ethics Committee of Jiangsu Provincial People's Hospital
Publications and helpful links
General Publications
- Mariotto AB, Yabroff KR, Shao Y, Feuer EJ, Brown ML. Projections of the cost of cancer care in the United States: 2010-2020. J Natl Cancer Inst. 2011 Jan 19;103(2):117-28. doi: 10.1093/jnci/djq495. Epub 2011 Jan 12. Erratum In: J Natl Cancer Inst. 2011 Apr 20;103(8):699.
- Han X, Qian W, Liu Y, Zheng T, Su XJ, Zhang PP, Chen Y, Hu LH, Li ZS. Effects of age, sex and pathological type on the risk of multiple polyps: A Chinese teaching hospital study. J Dig Dis. 2020 Sep;21(9):505-511. doi: 10.1111/1751-2980.12863.
- Song M, Emilsson L, Bozorg SR, Nguyen LH, Joshi AD, Staller K, Nayor J, Chan AT, Ludvigsson JF. Risk of colorectal cancer incidence and mortality after polypectomy: a Swedish record-linkage study. Lancet Gastroenterol Hepatol. 2020 Jun;5(6):537-547. doi: 10.1016/S2468-1253(20)30009-1. Epub 2020 Mar 17.
- Oines M, Helsingen LM, Bretthauer M, Emilsson L. Epidemiology and risk factors of colorectal polyps. Best Pract Res Clin Gastroenterol. 2017 Aug;31(4):419-424. doi: 10.1016/j.bpg.2017.06.004. Epub 2017 Jun 28.
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 2019-SR-340
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Polyp, Colonic
-
University of ManitobaActive, not recruitingPolyps | Colonic Polyp | Polyp of Colon | Colo-rectal Cancer | Colon Polyp | Rectal Polyp | Polyp RectalCanada
-
South Tyneside and Sunderland NHS Foundation TrustMedtronic; Newcastle University; North Wales Organisation for Randomised Trials...CompletedColonic Polyp | Colorectal Adenoma | Colorectal Polyp | Colorectal SSA | Colorectal Adenomatous Polyp | Sessile Serrated Adenoma | Sessile Colonic PolypUnited Kingdom
-
Vejle HospitalNot yet recruitingColorectal Cancer | Colonic Polyp | Colorectal Polyp | Shared Decision Making | Decision Aids | Rectal Polyp
-
Wulumuqi General Hospital of Lanzhou Military CommandAir Force Military Medical University, ChinaCompletedColonic Polyp | Intestinal PolypChina
-
Olympus Europe SE & Co. KGRecruitingColonic PolypSpain, Germany, Sweden
-
The University of Texas Health Science Center,...Recruiting
-
Unity Health TorontoRecruiting
-
Wuerzburg University HospitalCompleted
-
Valduce HospitalCompleted
-
Parc de Salut MarUnknown