Hypotension Prediction Index: Correlations Between Invasive and Non-invasive Pressure Points.

Hypotension Prediction Index: Correlations Between Invasive and Non-invasive Pressure Points

To evaluate the clinical performance of the Hypotension Prediction Index obtained from the continuous, non-invasive Clear Sight monitor.

Study Overview

• Status: Active, not recruiting
• Conditions: Hypotension
• Intervention / Treatment: Device: Non invasive arterial pressure monitoring

Detailed Description

To evaluate the clinical performance of the Hypotension Prediction Index obtained from the continuous, non-invasive ClearSight monitor.

• Study Type: Observational
• Enrollment (Estimated): 50

Contacts and Locations

Study Locations

• United States
  • California
    • Sacramento, California, United States, 95817
      • UC Davis Health System

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

All patents undergoing surgery with a planner arterial catheter placement

Description

Inclusion Criteria:

• All Patients 18 years or older undergoing surgery with the use of general anesthesia and with planned arterial catheter placement and use of the HPI monitor.

Exclusion Criteria:

• Adults unable to consent
• Individuals who are not yet adults ( infants, children teenagers)
• Pregnant Women
• Prisoners

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Surgery requiring Invasive arterial pressure monitoring; Patients undergoing elective surgery that requires Invasive arterial pressure monitoring as standard of care.	Device: Non invasive arterial pressure monitoring; Non invasive arterial pressure monitoring

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
HPI	Hypotension Prediction Index obtained from continuous, non-invasive ClearSight monitor will not differ significantly from the HPI concurrently obtained from the standard of care invasive radial arterial pressure monitor	During surgical procedure

Collaborators and Investigators

• Sponsor: University of California, Davis

Publications and helpful links

General Publications

• Sarhadi K, Hamman J, Avila J, Jian Z, Fleming NW. Hypotension prediction index: comparison between invasive and non-invasive pressure inputs. BMC Anesthesiol. 2025 Apr 29;25(1):221. doi: 10.1186/s12871-025-03086-y.

Study record dates

Study Major Dates

• Study Start (Actual): August 20, 2021
• Primary Completion (Estimated): August 20, 2026
• Study Completion (Estimated): August 20, 2026

Study Registration Dates

• First Submitted: August 24, 2021
• First Submitted That Met QC Criteria: August 24, 2021
• First Posted (Actual): August 27, 2021

Study Record Updates

• Last Update Posted (Actual): December 5, 2025
• Last Update Submitted That Met QC Criteria: December 3, 2025
• Last Verified: December 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Vascular Diseases; Cardiovascular Diseases; Hypotension
• Other Study ID Numbers: 1791102

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No