Fertility Preservation in Transgender Persons: A Retrospective Look

Fertility Preservation in Transgender Persons: A Retrospective Look at the Decision and a Survey of the Desire for Children.

Patients in this study will be asked how they feel about the decision to freeze gametes, using a validated questionnaire. In addition, a number of questions with free text fields will be included in the questionnaire to write down any reasons for their satisfaction or regret. In a second part, the intention to use the frozen material will be assessed. We focus on techniques with real perspectives (e.g. cryopreservation of oocytes and sperm cells) and not on techniques that are more experimental for later use (cryopreservation of ovarian and testicular tissue).

Study Overview

• Status: Completed
• Conditions: Fertility Preservation in Transgender Persons

• Study Type: Observational
• Enrollment (Actual): 20

Contacts and Locations

Study Locations

• Belgium
  • Ghent, Belgium, 9000
    • Ghent University Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 14 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

transgender personen

Description

Inclusion Criteria:

• Dutch speaking
• Sperm or oocyte preservation between june 2015 and june 2020. Survey in 2021

Exclusion Criteria:

• Ovarian and testicular tissue cryopreservation

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Retrospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Transgender people's retrospective view of the decision	Study of transgender persons' retrospective evaluation of the decision to freeze egg or sperm cells prior to gender-confirming hormonal or surgical treatment in transition	fertility preservation between june 2015 and june 2020 (5 years). Survey in 2021 (up to 7 years after preservation)
Satisfaction/ regret about the decision	Survey on the reasons for satisfaction/ regret regarding the decision to freeze egg cells or sperm cells prior to gender-confirming hormonal or surgical treatment in the context of transition	fertility preservation between june 2015 and june 2020 (5 years). Survey in 2021 (up to 7 years after preservation)
Intention	Examination of the intention to use the frozen egg cells or sperm cells to fulfil a desire to have children	fertility preservation between june 2015 and june 2020 (5 years). Survey in 2021 (up to 7 years after preservation)

Collaborators and Investigators

• Sponsor: University Hospital, Ghent
• Investigators: Principal Investigator: Stoop, University Hospital, Ghent

Study record dates

Study Major Dates

• Study Start (Actual): July 8, 2021
• Primary Completion (Actual): June 30, 2023
• Study Completion (Actual): June 30, 2023

Study Registration Dates

• First Submitted: September 15, 2021
• First Submitted That Met QC Criteria: November 2, 2021
• First Posted (Actual): November 15, 2021

Study Record Updates

• Last Update Posted (Actual): July 13, 2023
• Last Update Submitted That Met QC Criteria: July 12, 2023
• Last Verified: July 1, 2023

More Information

Terms related to this study

• Other Study ID Numbers: BC-09136