Incidence and Outcome of Acute Diverticulitis in Finland

Incidence of Acute Diverticulitis in Finland: Nationwide Register Study of Epidemiology and Outcome of Treatment Between 2009-19

The incidence of acute diverticulitis (AD), conservative vs. surgical treatment and outcome of patients are studied using national registries and patient charts from two hospitals between years 2009-19.

Study Overview

• Status: Recruiting
• Conditions: Acute Diverticulitis
• Intervention / Treatment: Other: patients with acute diverticulitis

Detailed Description

Acute diverticulitis (AD) of colon is increasing in Finland. Incidence, prevalence and mortality of AD of colon are investigated during 10-year period (2009-2019) in whole country. Epidemiological data is compared to data of acute appendicitis. Nationwide data of patients with AD are asked from Finnish Institute for Health and Welfare (THL). To compare registry-based nationwide data, patient charts from electronic database of two hospitals (Mikkeli Central Hospital and Tampere University Hospital) are reviewed from same study period. Patient characteristics, medication, treatment (conservative vs surgery), recurrence of AD and long-term outcome are recorded.

• Study Type: Observational
• Enrollment (Estimated): 15000

Contacts and Locations

• Study Contact: Name: Hannu EK Paajanen, MD; Phone Number: +358405263101; Email: paajanen@surffi.fi
• Study Contact Backup: Name: Tuomo Rantanen, MD; Phone Number: +358504028461; Email: tuomo.rantanen@kuh.fi

Study Locations

• Finland
  • Mikkeli, Finland, 50100
    • Recruiting
    • Mikkeli Central Hospital
    • Contact: Hannu EK Paajanen, MD; Phone Number: +358405263101; Email: paajanen@surffi.fi

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 14 years to 96 years (Adult, Older Adult)
• Accepts Healthy Volunteers: N/A

• Sampling Method: Non-Probability Sample

Study Population

patients with acute diverticulitis is whole Finland and in two study hospitals during years 2009-2019

Description

Inclusion Criteria:

• all patients with acute diverticulitis (K57) in Finland and in two hospitals

Exclusion Criteria:

• other reasons for acute or chronic abdominal pain

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Retrospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Rate of annual incidence and prevalence of acute diverticulitis	how many patients with acute diverticulitis are treated in all hospitals in Finland	January 2009-December 2019

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of patients with surgical or conservative treatment	Number of patients with conservative or surgical treatment of acute diverticulitis in two hospitals	January 2009-December 2019
Number of treatment complications and survival of patients with acute diverticulitis	outcome of patients with acute diverticulitis in two hospitals	January 2009-December 2019

Collaborators and Investigators

• Sponsor: Kuopio University Hospital
• Collaborators: Tampere University Hospital; Mikkeli Central Hospital
• Investigators: Principal Investigator: Hannu EK Paajanen, MD, Eastern Univerisity of Finland

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2009
• Primary Completion (Actual): December 1, 2021
• Study Completion (Estimated): December 31, 2024

Study Registration Dates

• First Submitted: October 25, 2021
• First Submitted That Met QC Criteria: December 3, 2021
• First Posted (Actual): December 17, 2021

Study Record Updates

• Last Update Posted (Actual): March 7, 2024
• Last Update Submitted That Met QC Criteria: March 6, 2024
• Last Verified: March 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Digestive System Diseases; Gastrointestinal Diseases; Gastroenteritis; Diverticular Diseases; Diverticulitis
• Other Study ID Numbers: 5200661

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No