Lumbosacral Transitional Vertebra Prevalence Among Egypt Population and Its Association With Lumbar Degeneration (LSTV)

Lumbosacral Transitional Vertebra(LSTV ) Prevalence in Egypt Population and Its Association With Lumbar Degeneration :Retrospective Evaluation of Consecutive Abdominal CT Scans

retrospective cross sectional study Study Setting: Cases will be recruited from the recorded data system at the department of diagnostic radiology, Assiut University.

Study Overview

• Status: Not yet recruiting
• Conditions: Lumbosacral Anomalies

Detailed Description

• Study subjects:

  1. Inclusion criteria:

     • All patients underwent MSCT KUB from 2022 till 2023
     • Age between 20-50 years old

  2. Exclusion criteria:

     • All cases below 20 and above 50 .
     • previous history of lumbar spine surgery;
     • non-degenerative pathologies in the lumbar spine which could interrupt the evaluation of lumbar spine degeneration, including spinal tumors, infections, and traumatic fractures;
     • images with poor quality

  3. Sample Size Calculation:

     The study will include all patients underwent KUB CT in Assuit university hospital.

     Objective of this research study will be accomplished through the following consecutive steps:

• Patient Enrolment and sample collection:

Sample are patients underwent MSCT KUB at our hospital , ASSUIT university at one year. Lumbosacral spine will be assessed for LSTV ,the patient images will be divided into two groups ,one which has LSTV as cases and other group with normal spine as control. both groups will be assessed for associated disc degeneration ,facet arthropathy sacroiliac joint degeneration ,paravertebral muscle volume and will be compared with control.

• Study Type: Observational
• Enrollment (Estimated): 500

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Probability Sample

Study Population

The study will include all patients underwent KUB CT in Assuit university hospital at one year.

Description

Inclusion Criteria:

• • All MSCT KUB studies from 2022 till 2023

  • age between 20-50

Exclusion Criteria:

• All cases below 20 and above 50 .
• previous history of lumbar spine surgery;
• non-degenerative pathologies in the lumbar spine which could interrupt the evaluation of lumbar spine degeneration, including spinal tumors, infections, and traumatic fractures;
• images with poor quality

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
LSTV group and control group
1 and 2; for cases with LSTV; for normal studies

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
prevalence	prevalence of LSTV among egyptians	one year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
correlation of LSTV with lumbar disc degeneration	association between LSTV and disc height ,segmental disc wedge angle and degree of disc prolapse(mild ,moderate ,severe)	one year
correlation of LSTV with facet joint arthropathy	fact joint arthropathy will be assessed as unilateral ,bilateral and its degree(mild ,moderate ,severe)	one year
correlation of LSTV with sacroiliac degeneration	sacroiliac joint will be assessed as unilateral ,bilateral and degree (mild ,moderate ,severe)	one year
correlation of LSTV with paravertebral muscle volume	bilateral psoas muscle volume in cubic centimeter	one year

Collaborators and Investigators

• Sponsor: Assiut University

Study record dates

Study Major Dates

• Study Start (Estimated): September 1, 2024
• Primary Completion (Estimated): September 1, 2025
• Study Completion (Estimated): December 1, 2025

Study Registration Dates

• First Submitted: August 7, 2024
• First Submitted That Met QC Criteria: August 20, 2024
• First Posted (Actual): August 22, 2024

Study Record Updates

• Last Update Posted (Actual): August 22, 2024
• Last Update Submitted That Met QC Criteria: August 20, 2024
• Last Verified: August 1, 2024

More Information

Terms related to this study

• Other Study ID Numbers: AssuitU12345

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No