Effects of Combined Exercise Training Modality

Effects of Combined Exercise Training Modality on Diaphragm Function and Performance

This study aims to investigate the effects of combined Inspiratory Muscle Training and aerobic exercise on diaphragm and pulmonary functions, respiratory muscle function, performance, and body composition

Study Overview

• Status: Active, not recruiting
• Conditions: Healthy Individuals (Controls)
• Intervention / Treatment: Other: combined inspiratory and aerobic exercise training; Other: aerobic exercise training

• Study Type: Interventional
• Enrollment (Estimated): 24
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey
  • Amasya, Turkey
    • Amasya University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:aged between 18 and 40 years who have physical activity levels above 600 MET-min/week -

Exclusion Criteria:Individuals who were diagnosed with any cardiopulmonary or other chronic diseases, have any infections or limitations preventing them from doing an activity during assessment or intervention, do exercise regularly, and have smoked over 10 pack-years

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Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Triple

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: combined inspiratory and aerobic exercise training	Other: combined inspiratory and aerobic exercise training; combined inspiratory and aerobic exercise training will be performed in healthy individuals
Experimental: aerobic exercise training	Other: aerobic exercise training; aerobic exercise training will be performed in healthy individuals

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Respiratory muscle strength	Maximal inspiratory and expiratory muscle strength will be evaluated using mouth pressure device .	First day
diaphragm thickness		Second day
diaphragm stiffness		Second day

Secondary Outcome Measures

Outcome Measure	Time Frame
Inspiratory muscle endurance	First day
FEV1	First day
FVC	First day
FEV1/FVC	First day
PEF	First day
FEF2575	First day
Running Based Anaerobic Sprint Test (RAST test)	Second day

Collaborators and Investigators

• Sponsor: Gazi University

Study record dates

Study Major Dates

• Study Start (Actual): December 12, 2023
• Primary Completion (Estimated): December 31, 2024
• Study Completion (Estimated): March 31, 2025

Study Registration Dates

• First Submitted: December 16, 2024
• First Submitted That Met QC Criteria: December 16, 2024
• First Posted (Actual): March 25, 2025

Study Record Updates

• Last Update Posted (Actual): March 25, 2025
• Last Update Submitted That Met QC Criteria: December 16, 2024
• Last Verified: December 1, 2024

More Information

Terms related to this study

• Other Study ID Numbers: 310783

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No