Dietary Acid Load and Oral Health Quality in Adolescents

January 27, 2025 updated by: Emine Elibol, Ankara Yildirim Beyazıt University

Investigating the Relationship Between Dietary Acid Load and Oral Health-Related Quality of Life in Adolescents

This study investigates the link between dietary acid load and oral health-related quality of life in 374 high school students (226 females, 148 males). Participants completed a demographic questionnaire, the OHIP-14 scale, and provided 24-hour dietary recalls. Dietary acid load was assessed using PRAL and NEAP calculations. Data analysis was performed with SPSS 24 to explore the impact of diet composition on adolescents' oral health.

Study Overview

Status

Completed

Conditions

Detailed Description

Introduction: Oral health plays a crucial role in the psychological and physical development of children and adolescents. The composition of the diet consumed significantly affects oral health.

Objective: This study aimed to examine the relationship between dietary acid load and oral health-related quality of life in adolescents.

Method: A total of 374 high school students (226 females, 148 males) participated in the study. Adolescents completed a demographic questionnaire and the Oral Health Impact Profile-14 (OHIP-14) scale, and 24-hour retrospective food consumption records were collected. Dietary acid load was assessed by calculating potential renal acid load (PRAL) and net endogenous acid production (NEAP) based on macronutrient and micronutrient intake from food records. Data analysis was conducted using the SPSS 24 software package.

Study Type

Observational

Enrollment (Actual)

374

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

      • Ankara, Turkey, 06760
        • Ankara Yıldırım Beyazıt University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

Community sample in Türkiye

Description

Inclusion Criteria:

  • 14-18 ages

Exclusion Criteria:

  • those with diagnosed eating disorders
  • those with diagnosed psychiatric
  • those with diagnosed cancer

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Adolescents
This study investigates the link between dietary acid load and oral health-related quality of life in 374 high school students (226 females, 148 males). Participants completed a demographic questionnaire, the OHIP-14 scale, and provided 24-hour dietary recalls. Dietary acid load was assessed using PRAL and NEAP calculations. Data analysis was performed with SPSS 24 to explore the impact of diet composition on adolescents' oral health.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Oral Health Impact Profile-14 Score
Time Frame: Baseline

This scale was used to assess the quality of life related to oral health and how oral health affects overall quality of life and general health.

The scale consists of 14 items with 5-point Likert-type questions (each option ranging from 0 to 4 points) and was designed using a five-choice scaling method. It was concluded that as the total score increased, the severity of the problem also increased, leading to a decrease in quality of life.

Baseline
Calculation of Dietary Acid Load
Time Frame: Baseline

Dietary acid load (DAL), potential renal acid load (PRAL), and net endogenous acid production (NEAP) were calculated based on the 24 hours food consumption record The formula for PRAL is as follows:

PRAL (mEq/day) = 0.4888 x protein (g/day) +0.0366 x phosphorus (mg/day)-0.0205 x potassium (mg/day) - 0.0125 x calcium (mg/day) - 0.0263 x magnesium (mg/day) NEAP (mEq/day) = [54.5 x protein (g/day) / potassium (mEq/day)] - 10.2 High and positive PRAL and NEAP values indicate a high dietary acid load.

Baseline

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Body weight
Time Frame: Baseline
Body weight in kg
Baseline
Height
Time Frame: Baseline
Height in cm
Baseline
Body Mass Index (BMI)
Time Frame: Baseline
Kilograms per square meter (kg/m2)
Baseline
Sociodemographic characteristics
Time Frame: Baseline
Sociodemographic characteristics will be assessed using a structured questionnaire developed by the researchers. The questionnaire will include items measuring age, gender, education level, and income status. The results will be presented as numbers and percentages for each characteristic.
Baseline

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2023

Primary Completion (Actual)

May 15, 2023

Study Completion (Actual)

June 15, 2024

Study Registration Dates

First Submitted

January 27, 2025

First Submitted That Met QC Criteria

January 27, 2025

First Posted (Actual)

March 25, 2025

Study Record Updates

Last Update Posted (Actual)

March 25, 2025

Last Update Submitted That Met QC Criteria

January 27, 2025

Last Verified

December 1, 2024

More Information

Terms related to this study

Other Study ID Numbers

  • AYBUELİBOL007

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Adolescent

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