Comparative Effects of Task Oriented Progressive Resistance Training and Modified Otago Exercise Among Stroke Patients.

May 5, 2026 updated by: Riphah International University

Comparative Effects of Task Oriented Progressive Resistance Training and Modified Otago Exercise on Balance and Lower Limb Motor Function Among Stroke Patients.

Comparative Effects of Task Oriented Progressive Resistance Training and Modified Otago Exercise on Balance and Lower Limb Motor Function Among Stroke Patients.

Study Overview

Status

Active, not recruiting

Conditions

Intervention / Treatment

Detailed Description

Stroke is a clinical syndrome marked by the sudden onset of localized neurological indications that persist longer than 24 hours or result in death. This definition includes stroke both due to infarction and due to hemorrhage. Stroke is the second or third most common cause of death, one of the main causes of adult disability worldwide, and a global health problem. The remaining 80% are due to ischemic stroke which itself has a number of different subtypes, including large artery disease, cardio embolism, and small vessel disease. This study aims to evaluate the effects of Task Related Progressive Resistance Training and Modified Otago Exercises on balance and lower limb motor function in stroke patients.

A randomized controlled trial will be conducted over eleven months. Fifty-two stroke patients aged 45 to 65 years will be selected using non-probability convenient sampling technique. Participants will be randomly allocated into two groups using a lottery method. Group A will receive Task-Oriented Progressive Resistance Training which includes functional strengthening activities targeting lower limb muscles, while Group B will undergo Modified Otago Exercise Program which involves balance and strength exercises used to prevent fall in stroke. Interventions will be carried out over eight weeks, with assessments conducted pre- and post-intervention using the Berg Balance Scale (for balance), Fugl-Meyer Assessment (for lower limb motor function) and Mini Mental State Examination (for cognitive function). Data will be analysed using SPSS version 26, applying parametric or non-parametric tests based on data normality.

Study Type

Interventional

Enrollment (Estimated)

52

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Pakistan
    • Punjab Province
      • Lahore, Punjab Province, Pakistan, 54000

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Adults aged 45 to 65 years. (9)
  • Both genders male and female.
  • Clinically diagnosed with ischemic stroke.
  • Chronic stroke patients 6 to 10 months.
  • Presence of hemiparesis with mild to moderate motor deficits FMA-LE score 34.
  • Cognitive impairment MMSE score more than 26.
  • Ability to walk at least 10 meters with or without an assistive device

Exclusion Criteria:

  • Dementia or major neurocognitive disorder. (6)
  • Complete paralysis or unable to participate in active exercise. (11)
  • Patients with severe joint pain or arthritis are excluded due to reduce risk of injury and avoid confounding factors.
  • Recent fractures, or other musculoskeletal issues limiting exercise participation.
  • Suffering from physical diseases that prevent full participation in training.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Modified otago exercises
Other: Modified otago exercise

Warm up Head, neck, back extension, trunk, and ankle movement

  • Muscle strengthening:

    • Front knee (3)
    • Back knee
    • Side hip
    • Calf raises
    • Toe rises

  • Balance training:

    • Knee bends
    • Backward walking
    • Walk and turn
    • Sideways walk
    • Heel toe stand
    • Heel toe walk
    • One leg stand
    • Heel walk
    • Toe walk
    • Heel toe backward walk
    • Sit to stand
    • Stair walk
Other Names:
  • MOE
Active Comparator: Task oriented progressive resistance training
Participants receive interventions 3 session per week for 4 weeks
Other: Task oriented progressive resistance training

Standing and reaching in different directions for objects beyond arm's length

  • Sit to stand from various chair heights to strengthen lower limb extensors (3)
  • Stepping forward and backward on blocks of various heights
  • Stepping sideways on blocks of various heights
  • Forward stepping on blocks of various heights
  • Heel raise and lower in standing to strengthen plantar flexors (3)

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Fugl-Meyer Assessment (FMA)
Time Frame: baseline to 4rth week
Fugl-Meyer Assessment of Lower Extremity (FMA-LE) total score interpretation ranges from 0 to 34, with higher scores indicating better motor function. Generally, a score of 34 represents normal function, while scores below 29 indicate varying degrees of disability. (15) All FMA-LE forms and subscales showed a high internal consistency (Cronbach's alpha>0.91).
baseline to 4rth week
Berg Balance Scale (BBS)
Time Frame: Baseline to 4rth week
The BBS is postural balance scale containing 14 items including standing and sitting unsupported, reaching forward, and placing the alternating foot on a stool. Administering the BBS takes approximately 15 min. Each of the 14 items are scored on a 5-level ordinal scale from 0 (-unable to perform or requiring help‖) to 4 (-normal performance‖), thus providing a potential maximum score of 56 points. (13) test-retest (ICC = 0.96; 95% CI, 0.93-0.98) and inter-rater (ICC = 0.93; 95% CI, 0.87-0.97) reliability was excellent
Baseline to 4rth week
Mini Mentel Scale (MMS)
Time Frame: baseline to 4rth week
The Mini-Mental State Examination (MMSE) is a brief test used to screen for cognitive impairment, particularly in older adults. It assesses different aspects of cognitive function, including orientation, attention, memory, and language. The MMSE is scored on a scale of 0-30, with a score of 24 or higher generally considered normal. (17) The Mini-Mental State Examination (MMSE) generally demonstrates good internal consistency reliability, as indicated by Cronbach's alpha values ranging from 0.78 to 0.81.
baseline to 4rth week

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Riphah International University

Investigators

  • Principal Investigator: Sabiha Arshad, Ms, Riphah International University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 5, 2025

Primary Completion (Estimated)

June 3, 2026

Study Completion (Estimated)

July 6, 2026

Study Registration Dates

First Submitted

May 5, 2026

First Submitted That Met QC Criteria

May 5, 2026

First Posted (Actual)

May 11, 2026

Study Record Updates

Last Update Posted (Actual)

May 11, 2026

Last Update Submitted That Met QC Criteria

May 5, 2026

Last Verified

May 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • REC/RCR&AHS/25/0214

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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