- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07649785
Static Stretching Reshapes Post-RT Recovery
June 10, 2026 updated by: Ewan Thomas, University of Palermo
Hemodynamic Load and Local Recovery Patterns After Resistance Training With and Without Static Stretching
This experimental study investigates the acute cardiovascular and local recovery to a single session of resistance training, with and without additional static stretching, compared with a resting control condition.
Participants are allocated to one of three groups (control, resistance training, resistance training plus static stretching) and assessed at baseline, immediately after the session, and 30 minutes post-exercise.
Primary outcomes include rate-pressure product and local muscle oxygen saturation, while secondary outcomes include heart rate, blood pressure, brachial artery diameter, tissue hardness, and pressure pain threshold.
These measures are used to characterize the short-term effects of the different experimental conditions on systemic hemodynamic load, vascular response, local muscle oxygenation, mechanical tissue status, and pressure pain sensitivity during early recovery.
Study Overview
Status
Completed
Intervention / Treatment
Study Type
Interventional
Enrollment (Actual)
28
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Italy
-
Palermo, Italy, Italy, 90144
- University of Palermo
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- healthy male participants ≥ 18 years old
Exclusion Criteria:
- orthopedic disorders
- neurological disorders
- metabolic disorders
- cardovascular disorders
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Basic Science
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: RT
Resistance Training
|
Participants assigned to this group will complete a single supervised upper body resistance training session.
The protocol includes bench presses and bicep curls performed at 100% of the individual's 8-rep max, for 4 sets of 8 reps, with standardized rest intervals between sets of 2 minutes.
The total duration of the session is approximately 20-25 minutes and does not include any additional static stretching beyond the standardized warm-up.
|
|
Experimental: RT+SS
Resistance Training + Static Stretching
|
Participants assigned to this group will complete a single supervised upper body resistance training session.
The protocol includes bench presses and bicep curls performed at 100% of the individual's 8-rep max, for 4 sets of 8 reps, with standardized rest intervals between sets of 2 minutes.
The total duration of the session is approximately 20-25 minutes .Immediately after the resistance exercises, they will complete a structured static stretching protocol targeting the trained muscle groups (pectoralis and elbow flexor), with each stretch held for about 30 seconds and repeated for several sets.
The additional stretching lasts 12 minutes, for a total session duration of about 30-35 minutes.
|
|
No Intervention: Control Condition(CC)
participants sat silently on a chair without performing any train
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Rate-Pressure Product (RPP)
Time Frame: 3 times (Baseline, immediately after intervantion and 30 minutes after intervention) for each condition (CC, RT, RT+ST)
|
Rate-pressure product (RPP) will be used as an index of myocardial workload and hemodynamic load during early post-exercise recovery.
RPP will be calculated as heart rate multiplied by systolic blood pressure (Omron MX3 Plus).
Heart rate and systolic blood pressure will be measured under standardized resting conditions at each time point.
|
3 times (Baseline, immediately after intervantion and 30 minutes after intervention) for each condition (CC, RT, RT+ST)
|
|
Local Muscle Oxygen Saturation (SmO₂)
Time Frame: Time Frame: 3 times (Baseline, immediately after intervantion and 30 minutes after intervention) for each condition (CC, RT, RT+ST)
|
Local muscle oxygen saturation (SmO₂) will be assessed using near-infrared spectroscopy (Moxy Monitor).
The sensor will be positioned over the target muscle region and secured to minimize movement artifacts.
SmO₂ will be recorded as a local index of the balance between oxygen delivery and oxygen utilization within the sampled muscle region.
|
Time Frame: 3 times (Baseline, immediately after intervantion and 30 minutes after intervention) for each condition (CC, RT, RT+ST)
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Brachial Artery diameter
Time Frame: Time Frame: 3 times (Baseline, immediately after intervention, and 30 minutes after intervention) for each condition (CC, RT, RT+SS)
|
Brachial artery diameter will be assessed using high-resolution B-mode ultrasound (Esaote MyLab X1 GO, linear-array transducer).
The brachial artery will be imaged under standardized conditions, and arterial diameter will be measured at each time point to assess acute changes in conduit artery size during early post-exercise recovery.
|
Time Frame: 3 times (Baseline, immediately after intervention, and 30 minutes after intervention) for each condition (CC, RT, RT+SS)
|
|
Tissue Hardness (TH)
Time Frame: Time Frame: 3 times (Baseline, immediately after intervention, and 30 minutes after intervention) for each condition (CC, RT, RT+SS)
|
Tissue hardness (TH) will be assessed using a tissue hardness meter/force gauge (Neutone) at selected muscle sites involved in the exercise protocol, including the pectoral and biceps regions.
Measurements will be performed under standardized participant positioning and probe placement conditions.
TH will be used as a local mechanical marker of the post-exercise tissue response.
|
Time Frame: 3 times (Baseline, immediately after intervention, and 30 minutes after intervention) for each condition (CC, RT, RT+SS)
|
|
Pain pressure Threshold(PPT)
Time Frame: Time Frame: 3 times (Baseline, immediately after intervention, and 30 minutes after intervention) for each condition (CC, RT, RT+SS)
|
Pressure pain threshold (PPT) will be assessed using a pressure algometer(WAGNER, FPX) at selected muscle sites involved in the exercise protocol.
The algometer will be applied perpendicular to the skin surface with gradually increasing pressure until the participant reports the first sensation of pain.
PPT will be used as a sensory marker of local pressure pain sensitivity during early recovery.
|
Time Frame: 3 times (Baseline, immediately after intervention, and 30 minutes after intervention) for each condition (CC, RT, RT+SS)
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
January 12, 2026
Primary Completion (Actual)
March 10, 2026
Study Completion (Actual)
March 10, 2026
Study Registration Dates
First Submitted
June 10, 2026
First Submitted That Met QC Criteria
June 10, 2026
First Posted (Actual)
June 16, 2026
Study Record Updates
Last Update Posted (Actual)
June 16, 2026
Last Update Submitted That Met QC Criteria
June 10, 2026
Last Verified
June 1, 2026
More Information
Terms related to this study
Additional Relevant MeSH Terms
- Motor Activity
- Movement
- Musculoskeletal Physiological Phenomena
- Musculoskeletal and Neural Physiological Phenomena
- Therapeutics
- Physical Therapy Modalities
- Patient Care
- Exercise Therapy
- Rehabilitation
- Aftercare
- Continuity of Patient Care
- Physical Conditioning, Human
- Exercise
- Resistance Training
- Muscle Stretching Exercises
Other Study ID Numbers
- 353/2025 SS
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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