Fatigability and Physical Performance: Effects of Resistance Training Variables Manipulation

August 6, 2018 updated by: Fábio Lera Orsatti, Universidade Federal do Triangulo Mineiro
This study evaluate whether resistance training variables modulate the fatigability (power-duration relationship) and physical performance in adults and older adults

Study Overview

Status

Unknown

Conditions

Intervention / Treatment

Detailed Description

The resistance training variables manipulation is utilized for maximize the results of resistance training. However it is unclear whether the resistance training variables manipulation modulates the fatigability (i.e. power-duration relationship) and whether this explains the improvement on physical performance (i.e. gait speed, sit-to-stand and timed up and go tests).

Study Type

Interventional

Enrollment (Anticipated)

80

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Brazil
    • MG - Minas Gerais
      • Uberaba, MG - Minas Gerais, Brazil, 38061-500
        • Recruiting
        • Post-degree program in physical education
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

50 years and older (ADULT, OLDER_ADULT)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

Female

Description

Inclusion Criteria:

  • Postmenopausal women (>12 months amenorrhea) with age above or equal 50 years old.
  • No hormone therapy or phytoestrogens

Exclusion Criteria:

  • No-drinker alcohol (no alcohol intake whatsoever in their diet);
  • Non- smokers;
  • Hypertensive with uncontrolled blood pressure values;
  • Diabetic with uncontrolled glycemia;
  • Presence of arthropathies;
  • Presence of myopathies;
  • Skeletal musculotendinous disorder.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: PREVENTION
  • Allocation: RANDOMIZED
  • Interventional Model: PARALLEL
  • Masking: NONE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
EXPERIMENTAL: Lower load resistance training (LL)
In the LL group, postmenopausal women will perform the resistance training with moderate volume (i.e. three sets per exercise performed until or close to failure) and low load (i.e. 30% of 1RM)
Other: Resistance training, LL
In LL, the postmenopausal women will be submitted to 12 weeks of Resistance training with moderate volume (i.e. three sets per exercise) and low load (i.e. 30% of one repetition maximum)
EXPERIMENTAL: Higher load resistance training (HL)
In the HL group, postmenopausal women will perform the resistance training with moderate volume (i.e. three sets per exercise performed until or close to failure) and high load (i.e. 80% of 1RM)
Other: Resistance training, HL
In HL, the postmenopausal women will be submitted to 12 weeks of Resistance training with moderate volume (i.e. three sets per exercise) and high load (i.e. 80% of one repetition maximum)
EXPERIMENTAL: Higher volume resistance training (HVHL)
In the HVHL group, postmenopausal women will perform the resistance training with high volume (i.e. six sets per exercise performed until or close to failure) and high load (i.e. 80% of 1RM)
Other: Resistance training, HVHL
In HVHL, the postmenopausal women will be submitted to 12 weeks of Resistance training with high volume (i.e. six sets per exercise) and hig load (i.e. 80% of one maximum repetition)
OTHER: Control group, (CG)
In CG, the postmenopausal women group will not perform exercise
Other: Control group, CG
The CG groups do not will performed the exercise.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Fatigability
Time Frame: Changes in fatigability measure (e.g. baseline and after 12 weeks of intervention)
The fatigability will be evaluate by 60 maximum voluntary isometric contractions (3 s contraction, 2 s rest) in knee extensors at 70 degree.
Changes in fatigability measure (e.g. baseline and after 12 weeks of intervention)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Physical Performance
Time Frame: Changes in physical performance measure (e.g. baseline and after 12 weeks of intervention)
The physical performance will be evaluate by gait speed tests (e.g. 10m walking at usual and fast pace, 400m walk at usual and fast pace).
Changes in physical performance measure (e.g. baseline and after 12 weeks of intervention)

Other Outcome Measures

Outcome Measure
Measure Description
Time Frame
Body composition
Time Frame: Changes in body composition (e.g. baseline and after 12 weeks of intervention)
The body composition will be evaluate by dual-energy X-ray absorptiometry (DXA).
Changes in body composition (e.g. baseline and after 12 weeks of intervention)
Muscle strength
Time Frame: Changes in muscle strength (e.g. baseline and after 12 weeks of intervention)
Muscle strength will be assess in all subjects, by the one-repetition maximum (1-RM) test, for dynamic exercises. The 1-RM is defined as the maximal weight that is lifted with proper body alignment and correct lifting technique.
Changes in muscle strength (e.g. baseline and after 12 weeks of intervention)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Universidade Federal do Triangulo Mineiro

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ACTUAL)

May 20, 2018

Primary Completion (ANTICIPATED)

September 30, 2018

Study Completion (ANTICIPATED)

November 15, 2018

Study Registration Dates

First Submitted

August 1, 2018

First Submitted That Met QC Criteria

August 1, 2018

First Posted (ACTUAL)

August 7, 2018

Study Record Updates

Last Update Posted (ACTUAL)

August 8, 2018

Last Update Submitted That Met QC Criteria

August 6, 2018

Last Verified

August 1, 2018

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 85052218.0.0000.5154

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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