- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07654153
Surgical Positions and Postoperative Atelectasis: A Lung Ultrasound Study
Evaluation of the Effect of Surgical Positions Under General Anesthesia on Postoperative Atelectasis Using Lung Ultrasonography
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Study Groups: Patients will be divided into 4 groups according to the surgical position to be given during the operation:
- Group 1 (Supine, n=25)
- Group 2 (Prone, n=25)
- Group 3 (Lateral Decubitus, n=25)
- Group 4 (Lithotomy, n=25) All patients will receive standard anesthesia induction and maintenance with 1 mcg/kg fentanyl citrate, 2 mg/kg propofol, 0.6 mg/kg rocuronium intravenously, followed by maintenance with desfluran at a MAC of 0.8-1.2 (if necessary). Patient demographic data (age, gender, height, weight, BMI, ASA score, comorbidities) and intraoperative data (heart rate, SpO2, mean arterial pressure, duration of surgery, surgical position, applied PEEP level) will be recorded.
Lung Ultrasonography (LUS) Protocol: LUS evaluation, Dr. The ultrasound will be performed by Burak Ağar using a Mindray ultrasound device [Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe]. LUS will be performed using a 12-zone protocol consisting of 6 standard zones (upper and lower quadrants of the anterior, lateral, and posterior regions) for both hemithoraxes. The evaluation will be performed at 3 different time points:
- Preoperative (T0): Immediately before anesthesia induction, in the supine position (Baseline).
- Postoperative (T1): Immediately before the patient is awakened, in the supine position.
Postoperative (T2): 20 minutes after the patient is transferred to the PACU. MLUS Scoring: Each region will be scored between 0-3 according to lung ventilation (MLUS Score):
- 0 Points: Normal ventilation (presence of A-line, fewer than 3 B-lines)
- 1 Point: Minor ventilation loss (≥ 3 B-lines or subpleural consolidations ≤ 1 cm in diameter separated by a normal pleural line)
- 2 Points: Moderate ventilation loss (Multiple small subpleural consolidations ≤ 1 cm in diameter separated by multiple and converging B-lines or a thickened/irregular pleural line)
- 3 Points: Severe ventilation loss (At least one consolidation > 1 cm in diameter or subpleural consolidations > 1x2 cm in diameter) The total MLUS score will be obtained by summing the scores of the 12 regions (Minimum 0, Maximum 36). Atelectasis will be defined as "predisposition to atelectasis when each quadrant score is 2 or 3".
Study Type
Enrollment (Estimated)
Contacts and Locations
Study Locations
-
-
Sivas
-
Sivas, Sivas, Turkey (Türkiye), 58140
- Sivas Cumhuriyet University
-
Contact:
- oğuz gündoğdu
- Phone Number: +905545945469
- Email: droguzgundogdu@gmail.com
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
- Being between 18-65 years of age
- Having ASA I-III status
- Planning elective surgery under general anesthesia
- Agreeing to participate in the study and signing the consent form
Exclusion Criteria:
- Patients requiring emergency surgery
- Patients with ASA IV or higher
- Presence of a known serious preoperative lung disease (COPD, Asthma, Pneumonia, Pleural effusion, Pneumothorax, Interstitial lung disease, Bronchiectasis, etc.)
- History of neuromuscular disease
- Body Mass Index (BMI) > 35 kg/m² (Morbid obesity)
- Presence of chest wall deformity or skin lesions that would obstruct LUS imaging
- Cases with an operative duration of less than 60 minutes or more than 300 minutes
- Patients with a history of thoracotomy, sternotomy, or prior open thoracic surgery
- Patients with alcohol or drug dependence
- Patients with significant anemia
- Patients who are pregnant or lactating
- Patients who develop laryngospasm following extubation
- Refusal to provide consent or inability to cooperate
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
|---|---|
|
Group 1
Supine position
|
Lung Ultrasound (LUS) Protocol: The LUS evaluation will be performed by Dr. Burak Ağar using a Mindray ultrasound device [Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe]
|
|
group 2
prone position
|
Lung Ultrasound (LUS) Protocol: The LUS evaluation will be performed by Dr. Burak Ağar using a Mindray ultrasound device [Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe]
|
|
group 3
lateral decubitus
|
Lung Ultrasound (LUS) Protocol: The LUS evaluation will be performed by Dr. Burak Ağar using a Mindray ultrasound device [Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe]
|
|
Group 4
lithotomy
|
Lung Ultrasound (LUS) Protocol: The LUS evaluation will be performed by Dr. Burak Ağar using a Mindray ultrasound device [Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe]
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Modified Lung Ultrasound Score
Time Frame: 1. (T0):Immediately before anesthesia induction, in the supine position 2.(T1): Immediately before the patient is awakened, in the supine posit 3.(T2):Twenty minutes after the patient was admitted to the PACU (Post-Anesthesia Care Unit)
|
MLUS Scoring: Each region will be scored between 0-3 according to lung ventilation (MLUS Score):
|
1. (T0):Immediately before anesthesia induction, in the supine position 2.(T1): Immediately before the patient is awakened, in the supine posit 3.(T2):Twenty minutes after the patient was admitted to the PACU (Post-Anesthesia Care Unit)
|
Collaborators and Investigators
Sponsor
Study record dates
Study Major Dates
Study Start (Estimated)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 2025-11/01
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Atelectasis
-
Seoul National University HospitalCompletedPulmonary Atelectasis, Postoperative | Atelectasis, CompressionKorea, Republic of
-
Vittore Buzzi Children's HospitalNot yet recruiting
-
Ankara Etlik City HospitalActive, not recruiting
-
Capital Medical UniversityRecruiting
-
Emory UniversityPEEP Medical, LLCCompletedPostoperative AtelectasisUnited States
-
Menoufia UniversityCompleted
-
Xuzhou Medical UniversityCompleted
-
Severance HospitalCompletedAtelectasis, PostoperativeKorea, Republic of
-
Ondokuz Mayıs UniversityRecruitingAtelectasis, PostoperativeTurkey (Türkiye)
-
Al-Azhar UniversityCompletedPulmonary Atelectasis, PostoperativeEgypt
Clinical Trials on lung ultrasound
-
Korgün ÖkmenNot yet recruitingIntraoperative Fluid Management
-
Kasr El Aini HospitalCompletedExta Vascular Lung WaterEgypt
-
Yale UniversityCompletedPneumonia | Pulmonary Edema | DyspneaUnited States
-
Assiut UniversityCompleted
-
University of MilanCompletedLung Cancer | Community Acquired Pneumonia | Pulmonary Embolism | PleuritisItaly
-
Kafrelsheikh UniversityCompletedIntensive Care Unit | Lung | Ultrasound | Extubation | Weaning | Mechanically Ventilation | DiaphragmEgypt
-
Groupe Hospitalier Paris Saint JosephHopital ForcillesActive, not recruitingCOVID-19 | Weaning Failure | ICU Acquired WeaknessFrance
-
Centre Hospitalier Universitaire DijonRecruiting
-
Xiangtan Central HospitalActive, not recruitingHeart Failure | Lung UltrasoundChina
-
Tanta UniversityRecruitingAcute Respiratory Distress Syndrome | Mechanical Ventilation Complication | Computed TomographyEgypt