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Surgical Positions and Postoperative Atelectasis: A Lung Ultrasound Study

18. juni 2026 opdateret af: Oguz Gundogdu, Cumhuriyet University

Evaluation of the Effect of Surgical Positions Under General Anesthesia on Postoperative Atelectasis Using Lung Ultrasonography

The aim of this study is to prospectively evaluate the effect of surgical position on the development of postoperative atelectasis in patients undergoing surgery in supine, prone, lateral decubitus, and lithotomy positions using lung ultrasonography (LUS), and to investigate whether there is a difference between these positions.

Studieoversigt

Status

Ikke rekrutterer endnu

Intervention / Behandling

Detaljeret beskrivelse

Study Groups: Patients will be divided into 4 groups according to the surgical position to be given during the operation:

  • Group 1 (Supine, n=25)
  • Group 2 (Prone, n=25)
  • Group 3 (Lateral Decubitus, n=25)
  • Group 4 (Lithotomy, n=25) All patients will receive standard anesthesia induction and maintenance with 1 mcg/kg fentanyl citrate, 2 mg/kg propofol, 0.6 mg/kg rocuronium intravenously, followed by maintenance with desfluran at a MAC of 0.8-1.2 (if necessary). Patient demographic data (age, gender, height, weight, BMI, ASA score, comorbidities) and intraoperative data (heart rate, SpO2, mean arterial pressure, duration of surgery, surgical position, applied PEEP level) will be recorded.

Lung Ultrasonography (LUS) Protocol: LUS evaluation, Dr. The ultrasound will be performed by Burak Ağar using a Mindray ultrasound device [Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe]. LUS will be performed using a 12-zone protocol consisting of 6 standard zones (upper and lower quadrants of the anterior, lateral, and posterior regions) for both hemithoraxes. The evaluation will be performed at 3 different time points:

  1. Preoperative (T0): Immediately before anesthesia induction, in the supine position (Baseline).
  2. Postoperative (T1): Immediately before the patient is awakened, in the supine position.
  3. Postoperative (T2): 20 minutes after the patient is transferred to the PACU. MLUS Scoring: Each region will be scored between 0-3 according to lung ventilation (MLUS Score):

    • 0 Points: Normal ventilation (presence of A-line, fewer than 3 B-lines)
    • 1 Point: Minor ventilation loss (≥ 3 B-lines or subpleural consolidations ≤ 1 cm in diameter separated by a normal pleural line)
    • 2 Points: Moderate ventilation loss (Multiple small subpleural consolidations ≤ 1 cm in diameter separated by multiple and converging B-lines or a thickened/irregular pleural line)
    • 3 Points: Severe ventilation loss (At least one consolidation > 1 cm in diameter or subpleural consolidations > 1x2 cm in diameter) The total MLUS score will be obtained by summing the scores of the 12 regions (Minimum 0, Maximum 36). Atelectasis will be defined as "predisposition to atelectasis when each quadrant score is 2 or 3".

Undersøgelsestype

Observationel

Tilmelding (Anslået)

100

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

  • Voksen
  • Ældre voksen

Tager imod sunde frivillige

Ja

Prøveudtagningsmetode

Sandsynlighedsprøve

Studiebefolkning

The study will include a total of 100 patients in 4 groups, aged 18-65 years, with an ASA (American Society of Anesthesiologists) physical status between I and III, who are scheduled to undergo general anesthesia in supine, prone, lateral decubitus, and lithotomy positions.

Beskrivelse

Inclusion Criteria:

  • Being between 18-65 years of age
  • Having ASA I-III status
  • Planning elective surgery under general anesthesia
  • Agreeing to participate in the study and signing the consent form

Exclusion Criteria:

  • Patients requiring emergency surgery
  • Patients with ASA IV or higher
  • Presence of a known serious preoperative lung disease (COPD, Asthma, Pneumonia, Pleural effusion, Pneumothorax, Interstitial lung disease, Bronchiectasis, etc.)
  • History of neuromuscular disease
  • Body Mass Index (BMI) > 35 kg/m² (Morbid obesity)
  • Presence of chest wall deformity or skin lesions that would obstruct LUS imaging
  • Cases with an operative duration of less than 60 minutes or more than 300 minutes
  • Patients with a history of thoracotomy, sternotomy, or prior open thoracic surgery
  • Patients with alcohol or drug dependence
  • Patients with significant anemia
  • Patients who are pregnant or lactating
  • Patients who develop laryngospasm following extubation
  • Refusal to provide consent or inability to cooperate

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Kohorter og interventioner

Gruppe / kohorte
Intervention / Behandling
Group 1
Supine position
Lung Ultrasound (LUS) Protocol: The LUS evaluation will be performed by Dr. Burak Ağar using a Mindray ultrasound device [Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe]
group 2
prone position
Lung Ultrasound (LUS) Protocol: The LUS evaluation will be performed by Dr. Burak Ağar using a Mindray ultrasound device [Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe]
group 3
lateral decubitus
Lung Ultrasound (LUS) Protocol: The LUS evaluation will be performed by Dr. Burak Ağar using a Mindray ultrasound device [Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe]
Group 4
lithotomy
Lung Ultrasound (LUS) Protocol: The LUS evaluation will be performed by Dr. Burak Ağar using a Mindray ultrasound device [Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe]

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Modified Lung Ultrasound Score
Tidsramme: 1. (T0):Immediately before anesthesia induction, in the supine position 2.(T1): Immediately before the patient is awakened, in the supine posit 3.(T2):Twenty minutes after the patient was admitted to the PACU (Post-Anesthesia Care Unit)

MLUS Scoring: Each region will be scored between 0-3 according to lung ventilation (MLUS Score):

  • 0 Points: Normal ventilation (presence of A-line, fewer than 3 B-lines)
  • 1 Point: Minor ventilation loss (≥ 3 B-lines or subpleural consolidations ≤ 1 cm in diameter separated by a normal pleural line)
  • 2 Points: Moderate ventilation loss (Multiple small subpleural consolidations ≤ 1 cm in diameter separated by multiple and converging B-lines or a thickened/irregular pleural line)
  • 3 Points: Severe ventilation loss (At least one consolidation > 1 cm in diameter or subpleural consolidations > 1x2 cm in diameter) The total MLUS score will be obtained by summing the scores of the 12 regions (Minimum 0, Maximum 36). Atelectasis will be defined as "predisposition to atelectasis when each quadrant score is 2 or 3"
1. (T0):Immediately before anesthesia induction, in the supine position 2.(T1): Immediately before the patient is awakened, in the supine posit 3.(T2):Twenty minutes after the patient was admitted to the PACU (Post-Anesthesia Care Unit)

Samarbejdspartnere og efterforskere

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Datoer for undersøgelser

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Studer store datoer

Studiestart (Anslået)

20. juli 2026

Primær færdiggørelse (Anslået)

20. juni 2027

Studieafslutning (Anslået)

1. august 2027

Datoer for studieregistrering

Først indsendt

12. juni 2026

Først indsendt, der opfyldte QC-kriterier

12. juni 2026

Først opslået (Faktiske)

17. juni 2026

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

22. juni 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

18. juni 2026

Sidst verificeret

1. juni 2026

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

  • 2025-11/01

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Kliniske forsøg med lung ultrasound

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