THRIVE-Belize: A School-Based Life-Skills Program to Support Teen Health in Toledo District, Belize (Feasibility) (THRIVE-Belize)

July 3, 2026 updated by: Mario Morales, University of Arizona

THRIVE-Belize: A Single-School Mixed-Methods Feasibility Trial of a Multi-Component Life-Skills Curriculum for Adolescent Health Promotion at Toledo Community College, Belize

THRIVE-Belize is a school-based program being developed to support the health and well-being of adolescents in the Toledo District of southern Belize. The program covers seven topics: communication and emotional regulation, healthy expressions of masculinity, sexual and reproductive health, healthy relationships, mental and physical health, substance use prevention, and environmental health.

Before testing whether the program works, the research team needs to learn whether students, teachers, parents, school staff, and community members find it acceptable, appropriate, and practical to deliver at Toledo Community College. This study (Phase I) does not deliver the program to anyone. Instead, it gathers feedback through surveys, focus groups, and interviews with about 280 participants across these five groups.

The information collected will be used to refine the program and decide whether to move forward to a future pilot study. No medical or educational intervention is given to participants in this phase.

Study Overview

Status

Not yet recruiting

Conditions

Study Type

Observational

Enrollment (Estimated)

280

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • Belize
    • Toledo District
      • Punta Gorda, Toledo District, Belize, 454V+3CH
        • Toledo Community College
        • Contact:
          • Shaunna Arnold Sanchez
          • Phone Number: 501 + 722-2101
          • Email: tccpg@btl.net

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

Adolescents aged 12-18 (Forms 1-4) and adult stakeholders (teachers, parents/guardians, principal and administrative staff, and community stakeholders) at one secondary school in the Toledo District, Belize.

Description

Inclusion Criteria:

  • Students: enrolled at Toledo Community College in Forms 1-4; ages 12-18 years; able to read and comprehend English at grade level; provides written assent; has active written parental/guardian consent
  • Teachers: currently employed at TCC; teaches students in Forms 1-4; provides written informed consent
  • Parents/Guardians: parent or legal guardian of an eligible TCC student; age 18 years or older; able to communicate in English, Spanish, or Q'eqchi'-Mopan Maya; provides written informed consent
  • School Principal and Administrative Staff: currently serving as principal or administrative staff at TCC; provides written informed consent
  • Community Stakeholders: recognized expertise in adolescent health, education, or youth services (e.g., healthcare providers, religious leaders, village council members, youth organization leaders); resident of Toledo District, Belize; provides written informed consent

Exclusion Criteria:

  • Cognitive or developmental limitations preventing informed assent or participation (students)
  • Declines to participate (students or parents/guardians)

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Students
TCC students in Forms 1-4, ages 12-18, providing feedback on the proposed curriculum via surveys, focus groups, and interviews.
Teachers
TCC teachers assigned to Forms 1-4, providing feedback via surveys, focus groups, and interviews.
Parents/Guardians
Parents or legal guardians of eligible TCC students, providing feedback via surveys, focus groups, and interviews.
School Principal and Administrative Staff
TCC principal and administrative staff, providing feedback via surveys and interviews.
Community Stakeholders
Toledo District community members with expertise in adolescent health, education, or youth services, providing feedback via surveys and interviews.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Acceptability of the proposed intervention (AIM)
Time Frame: Single timepoint at post-assessment data collection (study months 1-2)
Mean score on the adapted 4-item Acceptability of Intervention Measure (AIM), 5-point Likert scale (1=Strongly Disagree to 5=Strongly Agree). A mean score of 4.0 or higher indicates acceptability.
Single timepoint at post-assessment data collection (study months 1-2)
Appropriateness of the proposed intervention (IAM)
Time Frame: Single timepoint at post-assessment data collection (study months 1-2)
Mean score on the adapted 4-item Intervention Appropriateness Measure (IAM), 5-point Likert scale. A mean score of 4.0 or higher indicates appropriateness.
Single timepoint at post-assessment data collection (study months 1-2)
Feasibility of the proposed intervention (FIM)
Time Frame: Single timepoint at post-assessment data collection (study months 1-2)
Mean score on the adapted 4-item Feasibility of Intervention Measure (FIM), 5-point Likert scale. A mean score of 4.0 or higher indicates feasibility.
Single timepoint at post-assessment data collection (study months 1-2)
Adoption and organizational readiness
Time Frame: Single timepoint at post-assessment data collection (study months 1-2)
Proportion of stakeholders expressing intent to support or participate in the proposed intervention, supplemented by qualitative themes related to readiness and barriers from focus groups and interviews.
Single timepoint at post-assessment data collection (study months 1-2)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Recruitment and consent feasibility
Time Frame: Throughout the recruitment period (study months 1-2)
Consent/assent rates (target: at least 60%), retention rates, and reasons for non-participation.
Throughout the recruitment period (study months 1-2)
Measurement feasibility and respondent burden
Time Frame: Single timepoint at post-assessment data collection (study months 1-2)
Survey completion rates (target: at least 90%), item-level missingness, and participant-reported comprehension of instruments.
Single timepoint at post-assessment data collection (study months 1-2)
Facilitator and delivery feasibility
Time Frame: Single timepoint at post-assessment data collection (study months 1-2)
Qualitative assessment of teacher capacity, willingness to deliver the curriculum (target: at least 60% willing), training needs, and scheduling constraints.
Single timepoint at post-assessment data collection (study months 1-2)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Arizona

Collaborators

Hillside Health Care
Toledo Community College

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

July 1, 2026

Primary Completion (Estimated)

September 1, 2026

Study Completion (Estimated)

September 1, 2026

Study Registration Dates

First Submitted

June 29, 2026

First Submitted That Met QC Criteria

July 3, 2026

First Posted (Actual)

July 7, 2026

Study Record Updates

Last Update Posted (Actual)

July 7, 2026

Last Update Submitted That Met QC Criteria

July 3, 2026

Last Verified

July 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • STUDY00007955
  • MOHW/IRB/2026/002 (Other Identifier: Belize Ministry of Health and Wellness IRB)
  • GEN/21/26(112) VOL. III (Other Identifier: Belize Ministry of Education (MOECST))

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

No public release of individual participant data (IPD) is planned due to the small sample size and potential for re-identification in a single-school setting. De-identified aggregate data may be made available upon reasonable request following primary publication, subject to University of Arizona IRB approval, Belize Ministry of Health and Wellness IRB approval, and a formal data sharing agreement.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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