Study to Assess Effectiveness of Oral Atogepant in Adult Participants For Prevention of Migraine in the United Kingdom (PRACTICE)

Inclusion Criteria:

• Physician-confirmed diagnosis of migraine, classified as either episodic or chronic.
• Have at least 1-year history of migraine with or without aura consistent with a diagnosis according to the International Classification of Headache Disorders 3rd edition (ICHD-3), 2018.
• Without prior exposure to atogepant who are being prescribed atogepant in primary care for the prophylaxis of migraine with at least 4 migraine days per month.
• Decision to initiate atogepant was made by a prescribing general practitioner (GP) or appropriate primary care health care professional (HCP) within a primary care setting, prior to and independent of any decision to approach the patient regarding participation in the study.
• Willing and able to comply with the requirements of the study, including being able to read and comprehend written English at a level sufficient to understand and complete study patient-reported outcomes (PROs).
• Not on concomitant preventive medication for migraine or have been on a stable preventive medication for migraine for at least 3 months prior to enrolment.
• Access to a suitable device (e.g., laptop, tablet, or smartphone) to complete PRO measures.

Exclusion Criteria:

• Previously exposed to atogepant as routine therapy before the study period or from clinical trials experience prior to entry.
• Enrolled in any interventional studies that may include investigational compounds for migraine.
• Initiated on atogepant in secondary care and subsequently maintained in primary care.
• Initiated on atogepant in primary care following specialist input via an 'advice and guidance' pathway.
• Contraindications to atogepant administration as per local labelling.
• Pregnant or planning to be pregnant or women of childbearing potential not using contraception.
• In the opinion of the prescribing GP or appropriate primary care HCP, the patient has a history or current evidence of any condition that might interfere with the patient's ability to comply with the study requirements.