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Undersøgelse af effektiviteten og sikkerheden ved kombinationen af to FDA-godkendte orale lægemidler, Nebivolol og Valsartan til behandling af trin 1 eller 2 hypertension

28. marts 2014 opdateret af: Forest Laboratories

En multicenter, randomiseret, dobbeltblind, placebokontrolleret, 8-ugers undersøgelse til evaluering af sikkerheden og effektiviteten af nebivolol og valsartan givet som en fast dosiskombination hos patienter med trin 1 eller 2 essentiel hypertension

At evaluere effektiviteten og sikkerheden af fastdosis kombination af nebivolol og valsartan sammenlignet med monoterapi og placebo hos patienter med stadium 1 og stadium 2 hypertension.

Studieoversigt

Status

Afsluttet

Betingelser

Intervention / Behandling

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

4161

Fase

Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Forenede Stater
- Alabama
  - Birmingham, Alabama, Forenede Stater, 35216
    - Forest Investigative Site 1750
  - Birmingham, Alabama, Forenede Stater, 35235
    - Forest Investigative Site 1038
  - Birmingham, Alabama, Forenede Stater, 35235
    - Forest Investigative Site 1308
  - Birmingham, Alabama, Forenede Stater, 35242
    - Forest Investigative Site 1192
  - Birmingham, Alabama, Forenede Stater, 35294
    - Forest Investigative Site 1005
  - Foley, Alabama, Forenede Stater, 36535
    - Forest Investigative Site 1047
  - Gulf Shores, Alabama, Forenede Stater, 36542
    - Forest Investigative Site 1717
  - Mobile, Alabama, Forenede Stater, 36617
    - Forest Investigative Site 1056
  - Muscle Shoals, Alabama, Forenede Stater, 35662
    - Forest Investigative Site 1719
- Arizona
  - Glendale, Arizona, Forenede Stater, 85308
    - Forest Investigative Site 1145
  - Goodyear, Arizona, Forenede Stater, 85395
    - Forest Investigative Site 1703
  - Mesa, Arizona, Forenede Stater, 85202
    - Forest Investigative Site 1757
  - Phoenix, Arizona, Forenede Stater, 85015
    - Forest Investigative Site 1170
  - Phoenix, Arizona, Forenede Stater, 85018
    - Forest Investigative Site 1238
  - Phoenix, Arizona, Forenede Stater, 85020
    - Forest Investigative Site 1204
  - Phoenix, Arizona, Forenede Stater, 85020
    - Forest Investigative Site 1755
  - Phoenix, Arizona, Forenede Stater, 85032
    - Forest Investigative Site 1259
  - Phoenix, Arizona, Forenede Stater, 85050
    - Forest Investigative Site 1001
  - Scottsdale, Arizona, Forenede Stater, 85251
    - Forest Investigative Site 1078
  - Tempe, Arizona, Forenede Stater, 85282
    - Forest Investigative Site 1225
  - Tempe, Arizona, Forenede Stater, 85282
    - Forest Investigative Site 1712
  - Tempe, Arizona, Forenede Stater, 85283
    - Forest Investigative Site 1089
  - Tucson, Arizona, Forenede Stater, 85704
    - Forest Investigative Site 1065
  - Tucson, Arizona, Forenede Stater, 85712
    - Forest Investigative Site 1340
  - Tucson, Arizona, Forenede Stater, 85745
    - Forest Investigative Site 1331
- Arkansas
  - Little Rock, Arkansas, Forenede Stater, 72204
    - Forest Investigative Site 1290
  - Little Rock, Arkansas, Forenede Stater, 72211
    - Forest Investigative Site 1138
  - Pine Bluff, Arkansas, Forenede Stater, 71603
    - Forest Investigative Site 1371
  - Searcy, Arkansas, Forenede Stater, 72143
    - Forest Investigative Site 1220
- California
  - Buena Park, California, Forenede Stater, 90620
    - Forest Investigative Site 1063
  - Burbank, California, Forenede Stater, 91505
    - Forest Investigative Site 1743
  - Carmichael, California, Forenede Stater, 95608
    - Forest Investigative Site 1006
  - Chino, California, Forenede Stater, 91710
    - Forest Investigative Site 1384
  - Chula Vista, California, Forenede Stater, 91911
    - Forest Investigative Site 1190
  - Costa Mesa, California, Forenede Stater, 92626
    - Forest Investigative Site 1178
  - Diamond Bar, California, Forenede Stater, 91765
    - Forest Investigative Site 1043
  - Encinitas, California, Forenede Stater, 92024
    - Forest Investigative Site 1362
  - Fresno, California, Forenede Stater, 93721
    - Forest Investigative Site 1144
  - Fresno, California, Forenede Stater, 93726
    - Forest Investigative Site 1095
  - Garden Grove, California, Forenede Stater, 92844
    - Forest Investigative Site 1710
  - Greenbrae, California, Forenede Stater, 94904
    - Forest Investigative Site 1022
  - Huntington Beach, California, Forenede Stater, 92647
    - Forest Investigative Site 1370
  - Huntington Park, California, Forenede Stater, 90255
    - Forest Investigative Site 1704
  - Huntington Park, California, Forenede Stater, 90255
    - Forest Investigative Site 1725
  - La Mesa, California, Forenede Stater, 91942
    - Forest Investigative Site 1742
  - Lomita, California, Forenede Stater, 90717
    - Forest Investigative Site 1381
  - Long Beach, California, Forenede Stater, 90806
    - Forest Investigative Site 1706
  - Los Angelas, California, Forenede Stater, 90057
    - Forest Investigative Site 1248
  - Los Angelas, California, Forenede Stater, 90057
    - Forest Investigative Site 1785
  - Los Angeles, California, Forenede Stater, 90017
    - Forest Investigative Site 1029
  - Los Angeles, California, Forenede Stater, 90017
    - Forest Investigative Site 1361
  - Los Angeles, California, Forenede Stater, 90036
    - Forest Investigative Site 1102
  - Mission Hills, California, Forenede Stater, 91345
    - Forest Investigative Site 1054
  - Moreno Valley, California, Forenede Stater, 92553
    - Forest Investigative Site 1386
  - Newport Beach, California, Forenede Stater, 92663
    - Forest Investigative Site 1756
  - Northridge, California, Forenede Stater, 91325
    - Forest Investigative Site 1181
  - Orange, California, Forenede Stater, 92868
    - Forest Investigative Site 1212
  - Palm Springs, California, Forenede Stater, 92262
    - Forest Investigative Site 1101
  - Paramount, California, Forenede Stater, 90723
    - Forest Investigative Site 1014
  - Pismo Beach, California, Forenede Stater, 93449
    - Forest Investigative Site 1150
  - Riverside, California, Forenede Stater, 92506
    - Forest Investigative Site 1009
  - Roseville, California, Forenede Stater, 95661
    - Forest Investigative Site 1241
  - Sacramento, California, Forenede Stater, 95816
    - Forest Investigative Site 1046
  - Sacramento, California, Forenede Stater, 95821
    - Forest Investigative Site 1193
  - Sacramento, California, Forenede Stater, 95823
    - Forest Investigative Site 1296
  - Sacramento, California, Forenede Stater, 95825
    - Forest Investigative Site 1716
  - San Bernardino, California, Forenede Stater, 92404
    - Forest Investigative Site 1096
  - San Diego, California, Forenede Stater, 92056
    - Forest Investigative Site 1189
  - San Diego, California, Forenede Stater, 92103
    - Forest Investigative Site 1279
  - San Diego, California, Forenede Stater, 92114
    - Forest Investigative Site 1354
  - San Diego, California, Forenede Stater, 92117
    - Forest Investigative Site 1724
  - San Diego, California, Forenede Stater, 92120
    - Forest Investigative Site 1106
  - San Francisco, California, Forenede Stater, 94115
    - Forest Investigative Site 1027
  - San Marino, California, Forenede Stater, 91108
    - Forest Investigative Site 1017
  - San Ramon, California, Forenede Stater, 94583
    - Forest Investigative Site 1158
  - Santa Ana, California, Forenede Stater, 92705
    - Forest Investigative Site 1318
  - Spring Valley, California, Forenede Stater, 91978
    - Forest Investigative Site 1239
  - Stockton, California, Forenede Stater, 95204
    - Forest Investigative Site 1792
  - Sylmar, California, Forenede Stater, 91342
    - Forest Investigative Site 1301
  - Temecula, California, Forenede Stater, 92591
    - Forest Investigative Site 1066
  - Tustin, California, Forenede Stater, 92781
    - Forest Investigative Site 1729
  - Westlake Village, California, Forenede Stater, 91361
    - Forest Investigative Site 1783
- Colorado
  - Colorado Springs, Colorado, Forenede Stater, 80904
    - Forest Investigative Site 1162
  - Denver, Colorado, Forenede Stater, 80209
    - Forest Investigative Site 1270
  - Denver, Colorado, Forenede Stater, 80220
    - Forest Investigative Site 1711
  - Northglenn, Colorado, Forenede Stater, 80234
    - Forest Investigative Site 1013
  - Thornton, Colorado, Forenede Stater, 80233
    - Forest Investigative Site 1400
- Connecticut
  - Bridgeport, Connecticut, Forenede Stater, 06610
    - Forest Investigative Site 1324
  - Cromwell, Connecticut, Forenede Stater, 06416
    - Forest Investigative Site 1045
  - Stamford, Connecticut, Forenede Stater, 06905
    - Forest Investigative Site 1059
  - Waterbury, Connecticut, Forenede Stater, 06708
    - Forest Investigative Site 1072
- Florida
  - Boca Raton, Florida, Forenede Stater, 33432
    - Forest Investigative Site 1159
  - Bradenton, Florida, Forenede Stater, 34208
    - Forest Investigative Site 1007
  - Brandon, Florida, Forenede Stater, 33511
    - Forest Investigative Site 1042
  - Brooksville, Florida, Forenede Stater, 34601
    - Forest Investigative Site 1702
  - Clearwater, Florida, Forenede Stater, 33756
    - Forest Investigative Site 1764
  - Coral Gables, Florida, Forenede Stater, 33134
    - Forest Investigative Site 1182
  - Coral Gables, Florida, Forenede Stater, 33134
    - Forest Investigative Site 1249
  - Cutler Bay, Florida, Forenede Stater, 33189
    - Forest Investigative Site 1221
  - Daytona Beach, Florida, Forenede Stater, 32117
    - Forest Investigative Site 1793
  - DeFuniak Springs, Florida, Forenede Stater, 32435
    - Forest Investigative Site 1100
  - Deerfield Beach, Florida, Forenede Stater, 33441
    - Forest Investigative Site 1266
  - Deland, Florida, Forenede Stater, 32720
    - Forest Investigative Site 1734
  - Doral, Florida, Forenede Stater, 33166
    - Forest Investigative Site 1775
  - Doral, Florida, Forenede Stater, 33172
    - Forest Investigative Site 1378
  - Edgewater, Florida, Forenede Stater, 32132
    - Forest Investigative Site 1237
  - Fort Lauderdale, Florida, Forenede Stater, 33306
    - Forest Investigative Site 1068
  - Fort Lauderdale, Florida, Forenede Stater, 33319
    - Forest Investigative Site 1330
  - Ft. Lauderdale, Florida, Forenede Stater, 33308
    - Forest Investigative Site 1026
  - Gainsville, Florida, Forenede Stater, 32605
    - Forest Investigative Site 1794
  - Hallandale Beach, Florida, Forenede Stater, 33009
    - Forest Investigative Site 1261
  - Hialeah, Florida, Forenede Stater, 33012
    - Forest Investigative Site 1240
  - Hialeah, Florida, Forenede Stater, 33012
    - Forest Investigative Site 1260
  - Hollywood, Florida, Forenede Stater, 33021
    - Forest Investigative Site 1155
  - Jacksonville, Florida, Forenede Stater, 32216
    - Forest Investigative Site 1233
  - Jacksonville, Florida, Forenede Stater, 32216
    - Forest Investigative Site 1253
  - Jacksonville, Florida, Forenede Stater, 32216
    - Forest Investigative Site 1264
  - Jacksonville, Florida, Forenede Stater, 32223
    - Forest Investigative Site 1256
  - Jupiter, Florida, Forenede Stater, 33458
    - Forest Investigative Site 1077
  - Kissimmee, Florida, Forenede Stater, 34741
    - Forest Investigative Site 1041
  - Kissimmee, Florida, Forenede Stater, 34741
    - Forest Investigative Site 1399
  - Miami, Florida, Forenede Stater, 33014
    - Forest Investigative Site 1784
  - Miami, Florida, Forenede Stater, 33125
    - Forest Investigative Site 1364
  - Miami, Florida, Forenede Stater, 33135
    - Forest Investigative Site 1206
  - Miami, Florida, Forenede Stater, 33136
    - Forest Investigative Site 1397
  - Miami, Florida, Forenede Stater, 33143
    - Forest Investigative Site 1180
  - Miami, Florida, Forenede Stater, 33144
    - Forest Investigative Site 1396
  - Miami, Florida, Forenede Stater, 33155
    - Forest Investigative Site 1154
  - Miami, Florida, Forenede Stater, 33169
    - Forest Investigative Site 1788
  - Miami, Florida, Forenede Stater, 33183
    - Forest Investigative Site 1223
  - Miami, Florida, Forenede Stater, 33185
    - Forest Investigative Site 1707
  - Miami, Florida, Forenede Stater, 33186
    - Forest Investigative Site 1282
  - Miami Springs, Florida, Forenede Stater, 33166
    - Forest Investigative Site 1297
  - New Port Richey, Florida, Forenede Stater, 34652
    - Forest Investigative Site 1708
  - North Miami Beach, Florida, Forenede Stater, 33162
    - Forest Investigative Site 1176
  - Oldsmar, Florida, Forenede Stater, 34677
    - Forest Investigative Site 1284
  - Opa-Locka, Florida, Forenede Stater, 33054
    - Forest Investigative Site 1232
  - Orlando, Florida, Forenede Stater, 32806
    - Forest Investigative Site 1802
  - Orlando, Florida, Forenede Stater, 32811
    - Forest Investigative Site 1049
  - Orlando, Florida, Forenede Stater, 32822
    - Forest Investigative Site 1235
  - Ormond Beach, Florida, Forenede Stater, 32174
    - Forest Investigative Site 1741
  - Oviedo, Florida, Forenede Stater, 32765
    - Forest Investigative Site 1003
  - Palm Harbor, Florida, Forenede Stater, 34684
    - Forest Investigative Site 1369
  - Pembroke Pines, Florida, Forenede Stater, 33024
    - Forest Investigative Site 1079
  - Pembroke Pines, Florida, Forenede Stater, 33026
    - Forest Investigative Site 1053
  - Pembroke Pines, Florida, Forenede Stater, 33028
    - Forest Investigative Site 1055
  - Pembroke Pines, Florida, Forenede Stater, 33028
    - Forest Investigative Site 1161
  - Pembroke Pines, Florida, Forenede Stater, 33028
    - Forest Investigative Site 1166
  - Pembroke Pines, Florida, Forenede Stater, 33028
    - Forest Investigative Site 1224
  - Pembroke Pines, Florida, Forenede Stater, 33029
    - Forest Investigative Site 1075
  - Pinellas Park, Florida, Forenede Stater, 33782
    - Forest Investigative Site 1368
  - Plant City, Florida, Forenede Stater, 33563
    - Forest Investigative Site 1023
  - Ponte Vedra, Florida, Forenede Stater, 32081
    - Forest Investigative Site 1737
  - Port Orange, Florida, Forenede Stater, 32127
    - Forest Investigative Site 1749
  - South Miami, Florida, Forenede Stater, 33143
    - Forest Investigative Site 1739
  - St. Cloud, Florida, Forenede Stater, 34769
    - Forest Investigative Site 1069
  - St. Cloud, Florida, Forenede Stater, 34769
    - Forest Investigative Site 1315
  - St. Petersburg, Florida, Forenede Stater, 33701
    - Forest Investigative Site 1243
  - St. Petersburg, Florida, Forenede Stater, 33709
    - Forest Investigative Site 1723
  - St. Petersburg, Florida, Forenede Stater, 33716
    - Forest Investigative Site 1730
  - Tamarack, Florida, Forenede Stater, 33321
    - Forest Investigative Site 1076
  - Tampa, Florida, Forenede Stater, 33606
    - Forest Investigative Site 1032
  - Tampa, Florida, Forenede Stater, 33607
    - Forest Investigative Site 1302
  - Winter Haven, Florida, Forenede Stater, 33880
    - Forest Investigative Site 1120
- Georgia
  - Atlanta, Georgia, Forenede Stater, 30308
    - Forest Investigative Site 1281
  - Atlanta, Georgia, Forenede Stater, 30338
    - Forest Investigative Site 1745
  - Blue Ridge, Georgia, Forenede Stater, 30513
    - Forest Investigative Site 1080
  - Lilburn, Georgia, Forenede Stater, 30047
    - Forest Investigative Site 1236
  - Marietta, Georgia, Forenede Stater, 30060
    - Forest Investigative Site 1389
  - Marietta, Georgia, Forenede Stater, 30066
    - Forest Investigative Site 1002
  - Oakwood, Georgia, Forenede Stater, 30566
    - Forest Investigative Site 1390
  - Sandy Springs, Georgia, Forenede Stater, 30328
    - Forest Investigative Site 1333
  - Savannah, Georgia, Forenede Stater, 31419
    - Forest Investigative Site 1332
  - Snellville, Georgia, Forenede Stater, 30039
    - Forest Investigative Site 1252
  - Snellville, Georgia, Forenede Stater, 30078
    - Forest Investigative Site 1353
  - Stockbridge, Georgia, Forenede Stater, 30281
    - Forest Investigative Site 1740
  - Woodstock, Georgia, Forenede Stater, 30189
    - Forest Investigative Site 1173
- Hawaii
  - Honolulu, Hawaii, Forenede Stater, 96814
    - Forest Investigative Site 1018
- Idaho
  - Blackfoot, Idaho, Forenede Stater, 83221
    - Forest Investigative Site 1398
  - Boise, Idaho, Forenede Stater, 83704
    - Forest Investigative Site 1727
  - Hayden Lake, Idaho, Forenede Stater, 83835
    - Forest Investigative Site 1387
  - Meridian, Idaho, Forenede Stater, 83646
    - Forest Investigative Site 1004
  - Nampa, Idaho, Forenede Stater, 83686
    - Forest Investigative Site 1039
- Illinois
  - Addison, Illinois, Forenede Stater, 60101
    - Forest Investigative Site 1790
  - Arlington Heights, Illinois, Forenede Stater, 60004
    - Forest Investigative Site 1093
  - Chicago, Illinois, Forenede Stater, 60607
    - Forest Investigative Site 1747
  - Chicago, Illinois, Forenede Stater, 60611
    - Forest Investigative Site 1071
  - Chicago, Illinois, Forenede Stater, 60616
    - Forest Investigative Site 1752
  - Hazel Crest, Illinois, Forenede Stater, 60429
    - Forest Investigative Site 1403
  - Morton, Illinois, Forenede Stater, 61550
    - Forest Investigative Site 1126
  - O'Fallon, Illinois, Forenede Stater, 62269
    - Forest Investigative Site 1283
- Indiana
  - Evansville, Indiana, Forenede Stater, 47710
    - Forest Investigative Site 1091
  - Evansville, Indiana, Forenede Stater, 47712
    - Forest Investigative Site 1103
  - Muncie, Indiana, Forenede Stater, 47304
    - Forest Investigative Site 1147
- Kansas
  - Augusta, Kansas, Forenede Stater, 67010
    - Forest Investigative Site 1107
  - Hutchinson, Kansas, Forenede Stater, 67502
    - Forest Investigative Site 1345
  - Lenexa, Kansas, Forenede Stater, 66219
    - Forest Investigative Site 1805
  - Mission, Kansas, Forenede Stater, 66202
    - Forest Investigative Site 1255
  - Newton, Kansas, Forenede Stater, 67114
    - Forest Investigative Site 1092
- Kentucky
  - Crestview Hills, Kentucky, Forenede Stater, 41017
    - Forest Investigative Site 1801
  - Lexington, Kentucky, Forenede Stater, 40509
    - Forest Investigative Site 1366
  - Louisville, Kentucky, Forenede Stater, 40213
    - Forest Investigative Site 1770
  - Madisonville, Kentucky, Forenede Stater, 42431
    - Forest Investigative Site 1177
- Louisiana
  - Baton Rouge, Louisiana, Forenede Stater, 70808
    - Forest Investigative Site 1251
  - Covington, Louisiana, Forenede Stater, 70433
    - Forest Investigative Site 1215
  - Eunice, Louisiana, Forenede Stater, 70535
    - Forest Investigative Site 1274
  - Metairie, Louisiana, Forenede Stater, 70006
    - Forest Investigative Site 1323
  - Metairie, Louisiana, Forenede Stater, 77002
    - Forest Investigative Site 1795
  - New Orleans, Louisiana, Forenede Stater, 70115
    - Forest Investigative Site 1285
  - New Orleans, Louisiana, Forenede Stater, 70119
    - Forest Investigative Site 1779
- Maine
  - Auburn, Maine, Forenede Stater, 04210
    - Forest Investigative Site 1769
- Maryland
  - Baltimore, Maryland, Forenede Stater, 21209
    - Forest Investigative Site 1125
  - Baltimore, Maryland, Forenede Stater, 21236
    - Forest Investigative Site 1263
  - Lutherville, Maryland, Forenede Stater, 21093
    - Forest Investigative Site 1128
- Massachusetts
  - Haverhill, Massachusetts, Forenede Stater, 01830
    - Forest Investigative Site 1726
  - Hyannis, Massachusetts, Forenede Stater, 02601
    - Forest Investigative Site 1061
  - North Dartmouth, Massachusetts, Forenede Stater, 02747
    - Forest Investigative Site 1728
  - Watertown, Massachusetts, Forenede Stater, 02472-3930
    - Forest Investigative Site 1356
- Michigan
  - Chelsea, Michigan, Forenede Stater, 48118
    - Forest Investigative Site 1336
  - Flint, Michigan, Forenede Stater, 48504
    - Forest Investigative Site 1097
  - Kalamazoo, Michigan, Forenede Stater, 49009
    - Forest Investigative Site 1165
  - Stevensville, Michigan, Forenede Stater, 49127
    - Forest Investigative Site 1337
  - Traverse City, Michigan, Forenede Stater, 49684
    - Forest Investigative Site 1768
  - Troy, Michigan, Forenede Stater, 48085
    - Forest Investigative Site 1064
- Mississippi
  - Belzoni, Mississippi, Forenede Stater, 39038
    - Forest Investigative Site 1025
  - Jackson, Mississippi, Forenede Stater, 39289-1214
    - Forest Investigative Site 1057
  - Olive Branch, Mississippi, Forenede Stater, 38654
    - Forest Investigative Site 1034
  - Picayune, Mississippi, Forenede Stater, 39466
    - Forest Investigative Site 1271
- Missouri
  - Kansas City, Missouri, Forenede Stater, 64111
    - Forest Investigative Site 1782
  - St. Louis, Missouri, Forenede Stater, 63141
    - Forest Investigative Site 1250
- Montana
  - Missoula, Montana, Forenede Stater, 59808
    - Forest Investigative Site 1326
- Nebraska
  - Bellevue, Nebraska, Forenede Stater, 68005
    - Forest Investigative Site 1028
  - Fremont, Nebraska, Forenede Stater, 68025-2300
    - Forest Investigative Site 1388
  - Fremont, Nebraska, Forenede Stater, 68025
    - Forest Investigative Site 1313
  - Omaha, Nebraska, Forenede Stater, 68114
    - Forest Investigative Site 1035
  - Omaha, Nebraska, Forenede Stater, 68134
    - Forest Investigative Site 1016
  - Omaha, Nebraska, Forenede Stater, 68134
    - Forest Investigative Site 1254
  - Omaha, Nebraska, Forenede Stater, 68144
    - Forest Investigative Site 1148
- Nevada
  - Henderson, Nevada, Forenede Stater, 89014
    - Forest Investigative Site 1044
  - Henderson, Nevada, Forenede Stater, 89052
    - Forest Investigative Site 1052
  - Las Vegas, Nevada, Forenede Stater, 89101
    - Forest Investigative Site 1011
  - Las Vegas, Nevada, Forenede Stater, 89103
    - Forest Investigative Site 1376
  - Las Vegas, Nevada, Forenede Stater, 89104
    - Forest Investigative Site 1019
  - Las Vegas, Nevada, Forenede Stater, 89123
    - Forest Investigative Site 1807
  - Las Vegas, Nevada, Forenede Stater, 89148
    - Forest Investigative Site 1048
- New Jersey
  - Edison, New Jersey, Forenede Stater, 08817
    - Forest Investigative Site 1709
  - Haddon Heights, New Jersey, Forenede Stater, 08035
    - Forest Investigative Site 1132
  - Linden, New Jersey, Forenede Stater, 07036
    - Forest Investigative Site 1141
  - Paramus, New Jersey, Forenede Stater, 07652
    - Forest Investigative Site 1227
  - Trenton, New Jersey, Forenede Stater, 08611
    - Forest Investigative Site 1169
  - Union, New Jersey, Forenede Stater, 07083
    - Forest Investigative Site 1338
- New Mexico
  - Albuquerque, New Mexico, Forenede Stater, 87102
    - Forest Investigative Site 1761
- New York
  - Brooklyn, New York, Forenede Stater, 11203
    - Forest Investigative Site 1796
  - Buffalo, New York, Forenede Stater, 14215
    - Forest Investigative Site 1151
  - Glen Falls, New York, Forenede Stater, 12801
    - Forest Investigative Site 1021
  - Rochester, New York, Forenede Stater, 14609
    - Forest Investigative Site 1115
- North Carolina
  - Asheboro, North Carolina, Forenede Stater, 27203
    - Forest Investigative Site 1040
  - Burlington, North Carolina, Forenede Stater, 27215
    - Forest Investigative Site 1073
  - Cary, North Carolina, Forenede Stater, 27519
    - Forest Investigative Site 1142
  - Charlotte, North Carolina, Forenede Stater, 28209
    - Forest Investigative Site 1733
  - Charlotte, North Carolina, Forenede Stater, 28277
    - Forest Investigative Site 1067
  - Dunn, North Carolina, Forenede Stater, 28334
    - Forest Investigative Site 1342
  - Greensboro, North Carolina, Forenede Stater, 27401
    - Forest Investigative Site 1088
  - Greensboro, North Carolina, Forenede Stater, 27408
    - Forest Investigative Site 1385
  - Greensboro, North Carolina, Forenede Stater, 27410
    - Forest Investigative Site 1309
  - Hickory, North Carolina, Forenede Stater, 28601
    - Forest Investigative Site 1306
  - Hickory, North Carolina, Forenede Stater, 28602
    - Forest Investigative Site 1098
  - Lenoir, North Carolina, Forenede Stater, 28645
    - Forest Investigative Site 1110
  - Mooresville, North Carolina, Forenede Stater, 28117
    - Forest Investigative Site 1272
  - Raleigh, North Carolina, Forenede Stater, 27609
    - Forest Investigative Site 1024
  - Raleigh, North Carolina, Forenede Stater, 27612
    - Forest Investigative Site 1789
  - Salisbury, North Carolina, Forenede Stater, 28144
    - Forest Investigative Site 1715
  - Shelby, North Carolina, Forenede Stater, 28152
    - Forest Investigative Site 1123
  - Wilmington, North Carolina, Forenede Stater, 28401
    - Forest Investigative Site 1081
  - Wilmington, North Carolina, Forenede Stater, 28401
    - Forest Investigative Site 1705
  - Winston-Salem, North Carolina, Forenede Stater, 27103
    - Forest Investigative Site 1319
  - Winston-Salem, North Carolina, Forenede Stater, 27103
    - Forest Investigative Site 1405
  - Winston-Salem, North Carolina, Forenede Stater, 27103
    - Forest Investigative Site 1778
- Ohio
  - Akron, Ohio, Forenede Stater, 44311
    - Forest Investigative Site 1203
  - Canal Fulton, Ohio, Forenede Stater, 44614
    - Forest Investigative Site 1210
  - Cincinnati, Ohio, Forenede Stater, 45219
    - Forest Investigative Site 1012
  - Cincinnati, Ohio, Forenede Stater, 45219
    - Forest Investigative Site 1721
  - Cincinnati, Ohio, Forenede Stater, 45224
    - Forest Investigative Site 1280
  - Cincinnati, Ohio, Forenede Stater, 45227
    - Forest Investigative Site 1798
  - Cincinnati, Ohio, Forenede Stater, 45236
    - Forest Investigative Site 1732
  - Cincinnati, Ohio, Forenede Stater, 45242
    - Forest Investigative Site 1718
  - Cincinnati, Ohio, Forenede Stater, 45246
    - Forest Investigative Site 1062
  - Cincinnati, Ohio, Forenede Stater, 45249
    - Forest Investigative Site 1050
  - Cleveland, Ohio, Forenede Stater, 44122
    - Forest Investigative Site 1084
  - Columbus, Ohio, Forenede Stater, 43213
    - Forest Investigative Site 1765
  - Columbus, Ohio, Forenede Stater, 43214
    - Forest Investigative Site 1395
  - Delaware, Ohio, Forenede Stater, 43015
    - Forest Investigative Site 1209
  - Lyndhurst, Ohio, Forenede Stater, 44124
    - Forest Investigative Site 1201
  - Maumee, Ohio, Forenede Stater, 43537
    - Forest Investigative Site 1246
  - Mt. Gilead, Ohio, Forenede Stater, 43338
    - Forest Investigative Site 1135
  - Perrysburg, Ohio, Forenede Stater, 43551
    - Forest Investigative Site 1322
  - Willoughby, Ohio, Forenede Stater, 44094
    - Forest Investigative Site 1231
  - Zanesville, Ohio, Forenede Stater, 43701
    - Forest Investigative Site 1713
- Oklahoma
  - Norman, Oklahoma, Forenede Stater, 73069
    - Forest Investigative Site 1195
  - Oklahoma City, Oklahoma, Forenede Stater, 73103
    - Forest Investigative Site 1184
  - Oklahoma City, Oklahoma, Forenede Stater, 73103
    - Forest Investigative Site 1305
  - Oklahoma City, Oklahoma, Forenede Stater, 73103
    - Forest Investigative Site 1759
  - Yukon, Oklahoma, Forenede Stater, 73099
    - Forest Investigative Site 1392
- Oregon
  - Ashland, Oregon, Forenede Stater, 97520
    - Forest Investigative Site 1116
  - Eugene, Oregon, Forenede Stater, 97402
    - Forest Investigative Site 1379
  - Eugene, Oregon, Forenede Stater, 97404
    - Forest Investigative Site 1780
  - Hillsboro, Oregon, Forenede Stater, 97123-4147
    - Forest Investigative Site 1108
  - Portland, Oregon, Forenede Stater, 97225
    - Forest Investigative Site 1294
- Pennsylvania
  - Bensalem, Pennsylvania, Forenede Stater, 19020
    - Forest Investigative Site 1109
  - Bensalem, Pennsylvania, Forenede Stater, 19020
    - Forest Investigative Site 1291
  - Broomall, Pennsylvania, Forenede Stater, 19008
    - Forest Investigative Site 1090
  - Carnegie, Pennsylvania, Forenede Stater, 15106
    - Forest Investigative Site 1218
  - Downington, Pennsylvania, Forenede Stater, 19335
    - Forest Investigative Site 1163
  - Erie, Pennsylvania, Forenede Stater, 16508
    - Forest Investigative Site 1118
  - Erie, Pennsylvania, Forenede Stater, 16509
    - Forest Investigative Site 1171
  - Holland, Pennsylvania, Forenede Stater, 18966
    - Forest Investigative Site 1383
  - Jenkintown, Pennsylvania, Forenede Stater, 19046
    - Forest Investigative Site 1720
  - Lansdale, Pennsylvania, Forenede Stater, 19446
    - Forest Investigative Site 1207
  - Norristown, Pennsylvania, Forenede Stater, 19401
    - Forest Investigative Site 1314
  - Penndel, Pennsylvania, Forenede Stater, 19047
    - Forest Investigative Site 1198
  - Philadelphia, Pennsylvania, Forenede Stater, 19152
    - Forest Investigative Site 1293
  - Pittsburgh, Pennsylvania, Forenede Stater, 15216
    - Forest Investigative Site 1137
  - Red Lion, Pennsylvania, Forenede Stater, 17356
    - Forest Investigative Site 1247
  - Tipton, Pennsylvania, Forenede Stater, 16684
    - Forest Investigative Site 1791
  - Upper St. Clair, Pennsylvania, Forenede Stater, 15241
    - Forest Investigative Site 1196
  - Warminster, Pennsylvania, Forenede Stater, 18974
    - Forest Investigative Site 1172
  - West Chester, Pennsylvania, Forenede Stater, 19382
    - Forest Investigative Site 1278
- Rhode Island
  - Warwick, Rhode Island, Forenede Stater, 02886
    - Forest Investigative Site 1375
- South Carolina
  - Charleston, South Carolina, Forenede Stater, 29407
    - Forest Investigative Site 1760
  - Charleston, South Carolina, Forenede Stater, 29412
    - Forest Investigative Site 1363
  - Columbia, South Carolina, Forenede Stater, 29204
    - Forest Investigative Site 1122
  - Greenville, South Carolina, Forenede Stater, 29615
    - Forest Investigative Site 1133
  - Greenville, South Carolina, Forenede Stater, 29615
    - Forest Investigative Site 1809
  - Greer, South Carolina, Forenede Stater, 29651
    - Forest Investigative Site 1327
  - Mt. Pleasant, South Carolina, Forenede Stater, 29464
    - Forest Investigative Site 1127
  - Murrells Inlet, South Carolina, Forenede Stater, 29576
    - Forest Investigative Site 1310
  - Pelzer, South Carolina, Forenede Stater, 29669
    - Forest Investigative Site 1152
  - Simpsonville, South Carolina, Forenede Stater, 29681
    - Forest Investigative Site 1114
  - Spartanburg, South Carolina, Forenede Stater, 29303
    - Forest Investigative Site 1149
  - Summerville, South Carolina, Forenede Stater, 29485
    - Forest Investigative Site 1113
  - Union, South Carolina, Forenede Stater, 29379
    - Forest Investigative Site 1806
- South Dakota
  - Dakota Dunes, South Dakota, Forenede Stater, 57049
    - Forest Investigative Site 1185
  - Rapid City, South Dakota, Forenede Stater, 57702
    - Forest Investigative Site 1753
- Tennessee
  - Bristol, Tennessee, Forenede Stater, 37620
    - Forest Investigative Site 1402
  - Chattanooga, Tennessee, Forenede Stater, 37421
    - Forest Investigative Site 1037
  - Clarksville, Tennessee, Forenede Stater, 37043
    - Forest Investigative Site 1031
  - Collierville, Tennessee, Forenede Stater, 38107
    - Forest Investigative Site 1074
  - Fayetteville, Tennessee, Forenede Stater, 37334
    - Forest Investigative Site 1033
  - Kingsport, Tennessee, Forenede Stater, 37660
    - Forest Investigative Site 1763
  - Knoxville, Tennessee, Forenede Stater, 37920
    - Forest Investigative Site 1744
  - Memphis, Tennessee, Forenede Stater, 38119
    - Forest Investigative Site 1358
  - Memphis, Tennessee, Forenede Stater, 38125
    - Forest Investigative Site 1082
- Texas
  - Arlington, Texas, Forenede Stater, 76012
    - Forest Investigative Site 1094
  - Austin, Texas, Forenede Stater, 78728
    - Forest Investigative Site 1245
  - Austin, Texas, Forenede Stater, 78756
    - Forest Investigative Site 1311
  - Beaumont, Texas, Forenede Stater, 77701
    - Forest Investigative Site 1174
  - Boerne, Texas, Forenede Stater, 78006
    - Forest Investigative Site 1762
  - Bryan, Texas, Forenede Stater, 77802
    - Forest Investigative Site 1244
  - Carrollton, Texas, Forenede Stater, 75006
    - Forest Investigative Site 1776
  - Corpus Christi, Texas, Forenede Stater, 78404
    - Forest Investigative Site 1205
  - Corsicana, Texas, Forenede Stater, 75110
    - Forest Investigative Site 1268
  - Dallas, Texas, Forenede Stater, 75235
    - Forest Investigative Site 1213
  - Houston, Texas, Forenede Stater, 77024
    - Forest Investigative Site 1228
  - Houston, Texas, Forenede Stater, 77024
    - Forest Investigative Site 1372
  - Houston, Texas, Forenede Stater, 77030
    - Forest Investigative Site 1777
  - Houston, Texas, Forenede Stater, 77036
    - Forest Investigative Site 1157
  - Houston, Texas, Forenede Stater, 77062
    - Forest Investigative Site 1360
  - Houston, Texas, Forenede Stater, 77074
    - Forest Investigative Site 1230
  - Houston, Texas, Forenede Stater, 77081
    - Forest Investigative Site 1774
  - Irving, Texas, Forenede Stater, 75039
    - Forest Investigative Site 1262
  - Longview, Texas, Forenede Stater, 75605
    - Forest Investigative Site 1229
  - New Braunfels, Texas, Forenede Stater, 78130
    - Forest Investigative Site 1199
  - Plano, Texas, Forenede Stater, 75024
    - Forest Investigative Site 1214
  - San Antonio, Texas, Forenede Stater, 78205
    - Forest Investigative Site 1129
  - San Antonio, Texas, Forenede Stater, 78209
    - Forest Investigative Site 1766
  - San Antonio, Texas, Forenede Stater, 78215
    - Forest Investigative Site 1797
  - San Antonio, Texas, Forenede Stater, 78218
    - Forest Investigative Site 1295
  - San Antonio, Texas, Forenede Stater, 78229
    - Forest Investigative Site 1167
  - San Antonio, Texas, Forenede Stater, 78229
    - Forest Investigative Site 1186
  - San Antonio, Texas, Forenede Stater, 78229
    - Forest Investigative Site 1257
  - San Antonio, Texas, Forenede Stater, 78229
    - Forest Investigative Site 1317
  - San Antonio, Texas, Forenede Stater, 78229
    - Forest Investigative Site 1758
  - Sugar Land, Texas, Forenede Stater, 77478
    - Forest Investigative Site 1334
  - Tomball, Texas, Forenede Stater, 77375
    - Forest Investigative Site 1269
  - Waco, Texas, Forenede Stater, 76710
    - Forest Investigative Site 1349
- Utah
  - Clinton, Utah, Forenede Stater, 84015
    - Forest Investigative Site 1015
  - Draper, Utah, Forenede Stater, 84020
    - Forest Investigative Site 1187
  - Draper, Utah, Forenede Stater, 84020
    - Forest Investigative Site 1226
  - Magna, Utah, Forenede Stater, 84044
    - Forest Investigative Site 1086
  - Ogden, Utah, Forenede Stater, 84405
    - Forest Investigative Site 1216
  - Orem, Utah, Forenede Stater, 84058
    - Forest Investigative Site 1219
  - Riverton, Utah, Forenede Stater, 84065
    - Forest Investigative Site 1328
  - Salt Lake City, Utah, Forenede Stater, 84102
    - Forest Investigative Site 1771
  - Salt Lake City, Utah, Forenede Stater, 84107
    - Forest Investigative Site 1175
  - Salt Lake City, Utah, Forenede Stater, 84109
    - Forest Investigative Site 1197
  - Salt Lake City, Utah, Forenede Stater, 84121
    - Forest Investigative Site 1194
  - South Jordan, Utah, Forenede Stater, 84095
    - Forest Investigative Site 1202
  - St. George, Utah, Forenede Stater, 84790
    - Forest Investigative Site 1773
- Virginia
  - Arlington, Virginia, Forenede Stater, 22203
    - Forest Investigative Site 1786
  - Arlington, Virginia, Forenede Stater, 22205
    - Forest Investigative Site 1130
  - Burke, Virginia, Forenede Stater, 22015
    - Forest Investigative Site 1020
  - Danville, Virginia, Forenede Stater, 24541
    - Forest Investigative Site 1343
  - Manassas, Virginia, Forenede Stater, 20110
    - Forest Investigative Site 1164
  - Norfolk, Virginia, Forenede Stater, 23510
    - Forest Investigative Site 1767
  - Petersburg, Virginia, Forenede Stater, 23803
    - Forest Investigative Site 1292
  - Suffolk, Virginia, Forenede Stater, 23435
    - Forest Investigative Site 1131
  - Virginia Beach, Virginia, Forenede Stater, 23454
    - Forest Investigative Site 1099
- Washington
  - Port Orchard, Washington, Forenede Stater, 98366
    - Forest Investigative Site 1119
  - Seattle, Washington, Forenede Stater, 98104
    - Forest Investigative Site 1394
  - Spokane, Washington, Forenede Stater, 99207
    - Forest Investigative Site 1085
  - Walla Walla, Washington, Forenede Stater, 99362
    - Forest Investigative Site 1335
- West Virginia
  - Charleston, West Virginia, Forenede Stater, 25304
    - Forest Investigative Site 1377
- Wisconsin
  - Milwaukee, Wisconsin, Forenede Stater, 53215
    - Forest Investigative Site 1367

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Køn, der er berettiget til at studere

Alle

Beskrivelse

Inklusionskriterier:

Mandlige eller kvindelige ambulante patienter på 18 år eller derover
Patienter diagnosticeret med fase 1 eller fase 2 essentiel hypertension
Normale fysiske undersøgelsesresultater, elektrokardiogram (EKG) resultater og røntgen af thorax; eller unormale fund vurderet af investigator til ikke at være klinisk signifikante

Ekskluderingskriterier:

Sekundær hypertension eller svær hypertension
Klinisk signifikant kardiovaskulær sygdom eller hjertesvigt
Klinisk signifikant luftvejssygdom, der ville forbyde brugen af en betablokker
En medicinsk kontraindikation for at seponere en igangværende antihypertensiv behandling
Anamnese med type 1 diabetes mellitus
Anamnese med svær psykisk sygdom undtagen mild depression

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Primært formål: Behandling
Tildeling: Randomiseret
Interventionel model: Parallel tildeling
Maskning: Tredobbelt

Antal våben

Våben og indgreb

Deltagergruppe / Arm	Intervention / Behandling
Eksperimentel: Nebivolol og Valsartan fastdosiskombination 1 Fast dosiskombination Nebivolol 5 mg og Valsartan 80 mg	Medicin: Nebivolol og Valsartan 1 Fast dosis kombination Nebivolol 5 mg og Valsartan 80 mg, oral administration, derefter dosis fordoblet ved uge 11 til fast dosis kombination Nebivolol 10 mg og Valsartan 160 mg, oral administration
Eksperimentel: Nebivolol og Valsartan fastdosiskombination 2 Fast dosiskombination Nebivolol 5 mg og Valsartan 160 mg	Medicin: Nebivolol og Valsartan 2 Fast dosiskombination Nebivolol 5 mg og Valsartan 160 mg, oral administration, derefter fordoblet dosis ved uge 11 til fastdosiskombination Nebivolol 10 mg og Valsartan 320 mg, oral administration
Eksperimentel: Nebivolol og Valsartan fastdosiskombination 3 Fast dosiskombination Nebivolol 10 mg og Valsartan 160 mg	Medicin: Nebivolol og Valsartan 3 Fast dosiskombination Nebivolol 10 mg og Valsartan 160 mg, oral administration derefter fordoblet dosis ved uge 11 til fastdosiskombination Nebivolol 20 mg og Valsartan 320 mg, oral administration
Eksperimentel: Nebivolol lav dosis Nebivolol Monoterapi 5 mg	Medicin: Nebivolol 1 Nebivolol monoterapi 5 mg, oral administration, derefter fordoblet dosis til ved uge 11 til Nebivolol monoterapi 10 mg, oral administration
Eksperimentel: Nebivolol høj dosis Nebivolol Monoterapi 20 mg	Medicin: Nebivolol 2 Nebivolol monoterapi 20 mg, oral administration, derefter fordoblet dosis til ved uge 11 til Nebivolol monoterapi 40 mg, oral administration
Eksperimentel: Valsartan lav dosis Valsartan Monoterapi 80 mg	Medicin: Valsartan 1 Valsartan Monoterapi 80 mg, oral administration, derefter fordoblet dosis til ved uge 11 til Valsartan Monotherapy, 160 mg, oral administration
Eksperimentel: Valsartan høj dosis Valsartan Monoterapi 160 mg	Medicin: Valsartan 2 Valsartan Monoterapi 160 mg, oral administration, derefter fordoblet dosis til ved uge 11 til Valsartan Monotherapy, 320 mg, oral administration
Placebo komparator: Placebo Dosismatchet placebo	Medicin: Placebo Dosismatchet placebo, oral administration

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål	Tidsramme
Ændring i siddende diastolisk blodtryk (DBP) Tidsramme: fra basline til uge 8	fra basline til uge 8

Sekundære resultatmål

Resultatmål	Tidsramme
Ændring i siddende systolisk blodtryk (SBP) Tidsramme: fra baseline til uge 8	fra baseline til uge 8

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Forest Laboratories

Efterforskere

Studieleder: David B Bharucha, MD, PhD, FACC, Forest Laboratories

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Giles TD, Weber MA, Basile J, Gradman AH, Bharucha DB, Chen W, Pattathil M; NAC-MD-01 Study Investigators. Efficacy and safety of nebivolol and valsartan as fixed-dose combination in hypertension: a randomised, multicentre study. Lancet. 2014 May 31;383(9932):1889-98. doi: 10.1016/S0140-6736(14)60614-0. Erratum In: Lancet. 2016 Sep 24;388(10051):1280.

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart

1. januar 2012

Primær færdiggørelse (Faktiske)

1. marts 2013

Studieafslutning (Faktiske)

1. maj 2013

Datoer for studieregistrering

Først indsendt

9. januar 2012

Først indsendt, der opfyldte QC-kriterier

9. januar 2012

Først opslået (Skøn)

11. januar 2012

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Skøn)

25. april 2014

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

28. marts 2014

Sidst verificeret

1. marts 2014

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

NAC-MD-01

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Kliniske forsøg med Trin 2 Hypertension

Gachon University Gil Medical Center

Rekruttering

Klinisk forsøg til evaluering af effektiviteten og sikkerheden i samtidig administration af macitentan og dapagliflozin hos patienter med hjertesvigt med mildt reduceret og konserveret ejektionsfraktion (HFMREF og HFPEF) og kombineret præ- og postkapillær pulmonal hypertension (CPCPH)

HFpEF | Gruppe 2 Pulmonal hypertension | Kombineret præ- og postkapillær pulmonal hypertension | CPCPH | HFMREF

Sydkorea
Beni-Suef University

Aktiv, ikke rekrutterende

Fosfodiesterase Type 5-hæmmere hos patienter med gruppe 2-pulmonal hypertension

Gruppe 2 Pulmonal hypertension

Egypten
Salubris Biotherapeutics Inc

Trukket tilbage

Undersøgelse af JK07 hos patienter med hjertesvigt og WHO gruppe 2 kombineret post- og prækapillær pulmonal hypertension (RENEU-PH)

HFpEF - Hjertesvigt med bevaret ejektionsfraktion | HFrEF - Hjertesvigt med reduceret ejektionsfraktion | Gruppe 2 Pulmonal hypertension

Forenede Stater
AstraZeneca
Parexel

Afsluttet

En undersøgelse af AZD3427 hos deltagere med hjertesvigt og pulmonal hypertension gruppe 2 (Re-PHIRE)

Hjertefejl | Pulmonal hypertension (World Health Organization Group 2)

Forenede Stater, Canada, Tyskland, Italien, Holland, Spanien, Østrig, Det Forenede Kongerige, Polen, Tjekkiet, Kina, Danmark, Japan, Sverige
Novartis

Afsluttet

8 Weeks Study to Evaluate the Efficacy and Safety of Valsartan in Combination With Aliskiren Compared to Valsartan Alone in Patients With Stage 2 Hypertension (VANTAGE)

Trin 2 Hypertension

Forenede Stater
Gradient Denervation Technologies

Tilmelding efter invitation

LungearteriedenerVation Klinisk undersøgelse med anvendelse af gradientdenervationssystemet hos hjertesvigtpatienter med pulmonal hypertension gruppe 2 (PreVail-PH2-undersøgelse) (PreVail-PH2)

Hjertefejl | Gruppe 2 Pulmonal hypertension

Forenede Stater
SoniVie Inc.

Aktiv, ikke rekrutterende

REDUCERET 1 - Renal denervering ved hjælp af ultralydskateter-emitteret energiundersøgelse / (REDUCED)

Ukontrolleret trin 2 hypertension

Forenede Stater
University of Kansas Medical Center

Rekruttering

Pulmonal Hypertension Biorepository og Registry (PHBR)

Pulmonal arteriel hypertension | Pulmonal hypertension | Kronisk tromboembolisk pulmonal hypertension | Pulmonal hypertension på grund af venstre hjertesygdom | Pulmonal hypertension, primær, 4 | Pulmonal hypertension, primær, 2 | Pulmonal hypertension, primær, 3 | Pulmonal hypertension, primær | Pulmonal...

Forenede Stater
Forest Laboratories

Afsluttet

Effekt- og sikkerhedsundersøgelse til evaluering af kombinationsterapi med nebivolol og lisinopril vs. placebo og monoterapi hos patienter med trin 2 diastolisk hypertension

Fase 2 diastolisk hypertension

Forenede Stater, Puerto Rico
Ottawa Heart Institute Research Corporation

Afsluttet

Spironolactonterapi i kronisk stabil højre HF-forsøg (STAR-HF)

Pulmonal arteriel hypertension | Pulmonal hypertension, primær, 4 | Kronisk højresidig hjertesvigt | Pulmonal hypertension, primær, 2 | Pulmonal hypertension, primær, 3 | Kardiomyopati højre ventrikel

Canada

Kliniske forsøg med Nebivolol og Valsartan 1

Trinity Hypertension & Metabolic Research Institute
Allergan Sales, LLC

Afsluttet

Effekt og sikkerhed af Valsartan og Nebivolol/Valsartan hos hypertensive patienter med LVH (BVreduce)

Blodtryk | Hypertrofi, venstre ventrikel | Hypertension kompliceret

Forenede Stater
State University of New York at Buffalo

Afsluttet

24 timers ambulant hjerteiltforbrug (ACRPP)

Forhøjet blodtryk

Forenede Stater
Forest Laboratories

Afsluttet

Kombination af Nebivolol og Valsartan givet som gratis tabletter til trin 1 eller trin 2 hypertension

Forhøjet blodtryk

Forenede Stater
South Tyneside and Sunderland NHS Foundation Trust
EvoEndo, Inc.

Afsluttet

VRDD i øvre gastrointestinal endoskopi

Patienttilfredshed | Patientaccept af sundhedspleje

Det Forenede Kongerige
Bio-innova Co., Ltd

Ikke rekrutterer endnu

Nebivolol Tabletter 5 mg I forhold til Nebilet Tabletter 5 mg

Sunde emner
Novartis Pharmaceuticals

Afsluttet

Ændringer i NT-proBNP, sikkerhed og tolerabilitet hos HFpEF-patienter med en WHF-hændelse (HFpEF-dekompensation), som er blevet stabiliseret og påbegyndt på tidspunktet for eller inden for 30 dage efter dekompensation (PARAGLIDE-HF) (PARAGLIDE-HF)

Hjertesvigt med bevaret ejektionsfraktion (HFpEF)

Forenede Stater, Canada
Qingdao Central Hospital

Ikke rekrutterer endnu

Sacubitril/Valsartan versus Valsartan til hypertensive patienter med akut myokardieinfarkt

Myokardieinfarkt | Forhøjet blodtryk

Kina
University of Chicago

Afsluttet

Demonstration af Reverse Remodeling-effekter af Entresto. Brug af ekkokardiografi Endokardieoverfladeanalyse

Hjertefejl

Forenede Stater
Ain Shams University
National Cancer Institute, Egypt

Rekruttering

Evaluering af den kardioprotektive effekt af Nebivolol på trastuzumab-induceret kardiotoksicitet hos brystkræftpatienter

HER2-positiv brystkræft

Egypten
Novartis Pharmaceuticals

Afsluttet

Virkningerne af Sacubitril/Valsartan på hjertets iltforbrug og effektiviteten af hjertearbejde hos hjertesvigtpatienter (TurkuPET)

Hjertefejl

Finland

Undersøgelse af effektiviteten og sikkerheden ved kombinationen af ​​to FDA-godkendte orale lægemidler, Nebivolol og Valsartan til behandling af trin 1 eller 2 hypertension

En multicenter, randomiseret, dobbeltblind, placebokontrolleret, 8-ugers undersøgelse til evaluering af sikkerheden og effektiviteten af ​​nebivolol og valsartan givet som en fast dosiskombination hos patienter med trin 1 eller 2 essentiel hypertension

Studieoversigt

Status

Betingelser

Intervention / Behandling

Undersøgelsestype

Tilmelding (Faktiske)

Fase

Kontakter og lokationer

Studiesteder

Deltagelseskriterier

Berettigelseskriterier

Aldre berettiget til at studere

Tager imod sunde frivillige

Køn, der er berettiget til at studere

Beskrivelse

Studieplan

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Antal våben

Våben og indgreb

Deltagergruppe / Arm

Intervention / Behandling

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål

Tidsramme

Sekundære resultatmål

Resultatmål

Tidsramme

Samarbejdspartnere og efterforskere

Sponsor

Efterforskere

Publikationer og nyttige links

Generelle publikationer

Datoer for undersøgelser

Studer store datoer

Studiestart

Primær færdiggørelse (Faktiske)

Studieafslutning (Faktiske)

Datoer for studieregistrering

Først indsendt

Først indsendt, der opfyldte QC-kriterier

Først opslået (Skøn)

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Skøn)

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

Sidst verificeret

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

Kliniske forsøg med Trin 2 Hypertension

Kliniske forsøg med Nebivolol og Valsartan 1

Søg i lignende forsøg

Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

CROs by country

CROs in Morocco

Betingelser

Sjældne sygdomme

Narkotikainterventioner

Kosttilskud

Sponsor / samarbejdspartnere

Placeringer

Undersøgelse af effektiviteten og sikkerheden ved kombinationen af to FDA-godkendte orale lægemidler, Nebivolol og Valsartan til behandling af trin 1 eller 2 hypertension

En multicenter, randomiseret, dobbeltblind, placebokontrolleret, 8-ugers undersøgelse til evaluering af sikkerheden og effektiviteten af nebivolol og valsartan givet som en fast dosiskombination hos patienter med trin 1 eller 2 essentiel hypertension