The Effect of Transcranial Direct Stimulation on Cognitive Functions of Healthy Adults
The Effect Of Transcranial Direct Stimulation Applied To The Dorsolateral Prefrontal Cortex And Posterior Parietal Cortex İn Cognitive Function, Mood And Proprioception İn Healthy Adults
Background: Transcranial direct current stimulation(tDCS) has been used to improve cognitive functions in healthy young adults.
Purpose: To investigate the effect of TDCS application on different cortex regions on cognitive function.
Methods: Sixty individuals aged 18-30 were included in the study. The participants were randomly divided into the left dorsolateral prefrontal cortex (Left DLPFC Group)(n=20), the right posterior parietal cortex (Right PPC Group)(n=20), and the sham group (Sham Group)(n=20). tDCS was applied for 20 minutes on weekdays for 2 weeks. The participants were evaluated in terms of cognitive functions with Neuropsychometric Test Battery before and after treatment.
Studieoversigt
Status
Betingelser
Intervention / Behandling
Undersøgelsestype
Tilmelding (Faktiske)
Fase
- Ikke anvendelig
Kontakter og lokationer
Studiesteder
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Istanbul, Kalkun, 34000
- Damla Ören
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Istanbul, Kalkun, 34000
- Medipol Mega Hospital
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Deltagelseskriterier
Berettigelseskriterier
Aldre berettiget til at studere
Tager imod sunde frivillige
Køn, der er berettiget til at studere
Beskrivelse
Inclusion Criteria:
- being 18-30 years old
Exclusion Criteria:
- alcohol and substance addiction
- previous mental illness
- having mental and cognitive problems
- a history of head trauma
- having cardiovascular disease.
Studieplan
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Primært formål: Diagnostisk
- Tildeling: Randomiseret
- Interventionel model: Parallel tildeling
- Maskning: Enkelt
Våben og indgreb
Deltagergruppe / Arm |
Intervention / Behandling |
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Aktiv komparator: LEFT DLPFC
The anode electrode of tDCS was applied to the left DLPFC and the cathode electrode was connected to the contralateral shoulder.
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The intervention protocols were applied using tDCS (Teknofil TESsaNova).
All individuals received 2 mA of anodal tDCS for 2 weeks on weekdays.
All applications were done in the form of 20-minute sessions.
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Aktiv komparator: RİGHT PPC
The anode electrode of tDCS was applied to the right PPC and the cathode electrode was connected to the contralateral shoulder.
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The intervention protocols were applied using tDCS (Teknofil TESsaNova).
All individuals received 2 mA of anodal tDCS for 2 weeks on weekdays.
All applications were done in the form of 20-minute sessions.
|
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Sham-komparator: Sham
Placebo was applied by placing the electrodes in the right PPC and left DLPFC without applying current.
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The intervention protocols were applied using tDCS (Teknofil TESsaNova).
All individuals received 2 mA of anodal tDCS for 2 weeks on weekdays.
All applications were done in the form of 20-minute sessions.
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Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
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Neuropsychiatric Test Battery
Tidsramme: 3 weeks
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It is a test battery for getting detailed information about general cognitive status.
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3 weeks
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Beck Depression Scale
Tidsramme: 3 weeks
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It measures the symptoms seen in depression such as emotional, cognitive and motivational. It includes 21 items determine a behavioral feature related to depression. Items are numbered from 0 to 3. The goal is to objectively break down the degree of symptoms. The total score of all answers is calculated as follows: 0 to 9 points: Minimally depressive symptoms 10 to 16 points: Mild depressive symptoms Between 17 and 29 points: Moderate depressive symptoms Between 30 and 63 points: Severe depressive symptoms |
3 weeks
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Samarbejdspartnere og efterforskere
Sponsor
Efterforskere
- Studiestol: Lutfu Hanoglu, PhD, Medipol University
- Ledende efterforsker: Miray BUDAK, PhD, Medipol University
Datoer for undersøgelser
Studer store datoer
Studiestart (Faktiske)
Primær færdiggørelse (Faktiske)
Studieafslutning (Faktiske)
Datoer for studieregistrering
Først indsendt
Først indsendt, der opfyldte QC-kriterier
Først opslået (Faktiske)
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
Sidst verificeret
Mere information
Begreber relateret til denne undersøgelse
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- tDCS on DLPFC and PPC
Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter
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