- ICH GCP
- Registro de ensayos clínicos de EE. UU.
- Ensayo clínico NCT04693117
Functional Impact of Interval Training on Muscle Mass and Strength in Obese Adults
The primary objective was to investigate the effectiveness of interval training and to evaluate the best available method for measuring body composition and functional capacity.
Thirty obese subjects consecutively voluntarily participated in the current study. They ranked sedentary according to their level of activity (≥ 30-minute moderate physical activity 3days/wk). The training sessions were divided into the warm-up phase, training phase and a cool-down phase. The training programs were completed 3days/week for 12 weeks. Body composition was calculated by skinfold thickness method and bio-impedance before and after training. Similarly, aerobic capacities were measured by lactate threshold testing and by Astrand submaximal testing.
Descripción general del estudio
Estado
Condiciones
Intervención / Tratamiento
Tipo de estudio
Inscripción (Actual)
Fase
- No aplica
Contactos y Ubicaciones
Ubicaciones de estudio
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Punjab
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Lahore, Punjab, Pakistán, 54000
- Riphah Rehabilitation Center
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Criterios de participación
Criterio de elegibilidad
Edades elegibles para estudiar
Acepta Voluntarios Saludables
Géneros elegibles para el estudio
Descripción
Inclusion Criteria:
- 30 obese (BMI ≥ 30) and
- Sedentary lifestyle subjects (sample size was calculated by using WHO sample size calculator)
- Age 30-45 years and
- Hypercholesteremia
Exclusion Criteria:
- hypertension,
- diabetes,
- cardiovascular diseases
- systemic diseases
Plan de estudios
¿Cómo está diseñado el estudio?
Detalles de diseño
- Propósito principal: Investigación de servicios de salud
- Asignación: N / A
- Modelo Intervencionista: Asignación de un solo grupo
- Enmascaramiento: Ninguno (etiqueta abierta)
Armas e Intervenciones
Grupo de participantes/brazo |
Intervención / Tratamiento |
|---|---|
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Experimental: Study Group
Participants were voluntarily participated by non-probability consecutive sampling.
It was a one group study with a limitation of non-randomization.
The interventional group had performed interval training for 12 weeks, 3 days/week (figure 1).
They sedentary conferring to activity level (≥ 30-minute, 3 days/weeks, moderate-intensity physical activity).
They were not participated in any interval training program before participating in the study from six months.
Written consent was taken after demonstration of the purpose, procedure, and related pros and cons.
They were instructed to participate regularly in interval training.
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All individual of interventional group participated in an interval training program, which comprised of 3 days/week for twelve weeks.
A booklet was given to each participant containing instructions and guideline about interval training.
The interval training program was introduced as prescribed previously.17
After the workout, a cool down period of 5 minutes was given during which they perform paddling with low speed.
All training program was supervised by a qualified physical therapist.
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¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
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Anthropometric measurement (Body Mass Index)
Periodo de tiempo: 3 months
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Body Mass Index: BMI Weight Status Below 18.5 Underweight 18.5 - 24.9 Normal or Healthy Weight 25.0 - 29.9 Overweight 30.0 and Above Obese |
3 months
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Functional capacity
Periodo de tiempo: 3 Months
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The functional capacity was assessed by lactate threshold level and by Astrand submaximal testing by using standardized protocol. Lactate inflection point (LIP), is the exercise intensity at which the blood concentration of lactate and/or lactic acid begins to increase rapidly. It is often expressed as 85% of maximum heart rate or 75% of maximum oxygen intake. |
3 Months
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Anthropometric measurement (Lean body mass)
Periodo de tiempo: 3 months
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Lean body mass:Lean body mass is calculated as the difference between total body weight and body fat weight, or more simply, the weight of everything except the fat.
The range of lean body mass considered to be healthy is around 70% - 90% with women being towards the lower end of the range and men higher.
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3 months
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Functional Capacity
Periodo de tiempo: 3 months
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The functional capacity was assessed by Astrand submaximal testing by using standardized protocol. The Astrand Test is a submaximal cycle ergometer aerobic fitness test best suited in rehabilitation and health purposes. description: Athletes pedal on a cycle ergometer at a constant workload for 7 minutes. Heart rate is measured every minute, and the steady state heart rate is determined. |
3 months
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Colaboradores e Investigadores
Patrocinador
Publicaciones y enlaces útiles
Publicaciones Generales
- Sydo N, Abdelmoneim SS, Mulvagh SL, Merkely B, Gulati M, Allison TG. Relationship between exercise heart rate and age in men vs women. Mayo Clin Proc. 2014 Dec;89(12):1664-72. doi: 10.1016/j.mayocp.2014.08.018. Epub 2014 Oct 29.
- Al-Shawwa B, Al-Huniti N, Titus G, Abu-Hasan M. Hypercholesterolemia is a potential risk factor for asthma. J Asthma. 2006 Apr;43(3):231-3. doi: 10.1080/02770900600567056.
- Sobol NA, Hoffmann K, Frederiksen KS, Vogel A, Vestergaard K, Braendgaard H, Gottrup H, Lolk A, Wermuth L, Jakobsen S, Laugesen L, Gergelyffy R, Hogh P, Bjerregaard E, Siersma V, Andersen BB, Johannsen P, Waldemar G, Hasselbalch SG, Beyer N. Effect of aerobic exercise on physical performance in patients with Alzheimer's disease. Alzheimers Dement. 2016 Dec;12(12):1207-1215. doi: 10.1016/j.jalz.2016.05.004. Epub 2016 Jun 23.
- Faude O, Kindermann W, Meyer T. Lactate threshold concepts: how valid are they? Sports Med. 2009;39(6):469-90. doi: 10.2165/00007256-200939060-00003.
- Donges CE, Duffield R, Drinkwater EJ. Effects of resistance or aerobic exercise training on interleukin-6, C-reactive protein, and body composition. Med Sci Sports Exerc. 2010 Feb;42(2):304-13. doi: 10.1249/MSS.0b013e3181b117ca.
- Kiss O, Sydo N, Vargha P, Edes E, Merkely G, Sydo T, Merkely B. Prevalence of physiological and pathological electrocardiographic findings in Hungarian athletes. Acta Physiol Hung. 2015 Jun;102(2):228-37. doi: 10.1556/036.102.2015.2.13.
Fechas de registro del estudio
Fechas importantes del estudio
Inicio del estudio (Actual)
Finalización primaria (Actual)
Finalización del estudio (Actual)
Fechas de registro del estudio
Enviado por primera vez
Primero enviado que cumplió con los criterios de control de calidad
Publicado por primera vez (Actual)
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
Última actualización enviada que cumplió con los criterios de control de calidad
Última verificación
Más información
Términos relacionados con este estudio
Palabras clave
Términos MeSH relevantes adicionales
Otros números de identificación del estudio
- REC/Lhr/338
Plan de datos de participantes individuales (IPD)
¿Planea compartir datos de participantes individuales (IPD)?
Información sobre medicamentos y dispositivos, documentos del estudio
Estudia un producto farmacéutico regulado por la FDA de EE. UU.
Estudia un producto de dispositivo regulado por la FDA de EE. UU.
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