Esta página se tradujo automáticamente y no se garantiza la precisión de la traducción. por favor refiérase a versión inglesa para un texto fuente.

Comparison of Box Breathing and Rhythmic Breathing Techniques in Patients With Asthma (BRAS)

17 de julio de 2026 actualizado por: Riphah International University

Comparative Effects of Box and Rhythmic Breathing Techniques on Dyspnea, Pulmonary Functions, and Quality of Sleep Among Asthmatic Patients

Asthma is a chronic respiratory disease that can cause breathing difficulties, reduced lung function, and poor sleep quality. Breathing exercises are increasingly used as non-pharmacological interventions to improve respiratory symptoms and overall well-being in individuals with asthma.

This study aims to compare the effects of two breathing techniques, Box Breathing and Rhythmic Breathing, on dyspnea (breathlessness), pulmonary function, and quality of sleep in patients with asthma. Participants with asthma will be randomly assigned to receive either Box Breathing or Rhythmic Breathing exercises in addition to standard care. Both interventions will be performed three times per week for eight weeks.

The primary outcomes of this study include changes in dyspnea severity, pulmonary function measured by spirometry, and sleep quality assessed using validated questionnaires. The findings of this study may help determine which breathing technique is more effective and provide evidence for incorporating structured breathing exercises into asthma management programs.

Descripción general del estudio

Estado

Aún no reclutando

Condiciones

Intervención / Tratamiento

Descripción detallada

Asthma is a chronic inflammatory airway disease characterized by recurrent episodes of dyspnea, airflow limitation, and impaired quality of life. In addition to respiratory symptoms, many individuals with asthma experience sleep disturbances and reduced functional capacity. Breathing exercises have emerged as important non-pharmacological interventions that may improve respiratory control, autonomic regulation, and symptom perception.

Box Breathing and Rhythmic Breathing are structured breathing techniques that have shown potential benefits in respiratory rehabilitation. Box Breathing involves a controlled breathing pattern consisting of equal durations of inhalation, breath holding, exhalation, and breath holding. Rhythmic Breathing involves continuous and controlled breathing with a prolonged expiratory phase to promote respiratory efficiency and relaxation. However, limited evidence exists regarding the comparative effectiveness of these techniques in individuals with asthma.

The purpose of this study is to compare the effects of Box Breathing and Rhythmic Breathing on dyspnea, pulmonary function, and sleep quality among patients with asthma. Participants will receive standardized baseline respiratory care followed by either Box Breathing or Rhythmic Breathing interventions for eight weeks. The interventions are designed to improve breathing patterns, reduce breathlessness, enhance pulmonary function, and improve sleep quality.

This study aims to provide evidence regarding the effectiveness of structured breathing techniques as adjunctive interventions in asthma management. The findings may contribute to the development of evidence-based respiratory rehabilitation protocols and support the integration of breathing exercises into comprehensive asthma care programs.

Tipo de estudio

Intervencionista

Inscripción (Estimado)

36

Fase

  • No aplica

Contactos y Ubicaciones

Esta sección proporciona los datos de contacto de quienes realizan el estudio e información sobre dónde se lleva a cabo este estudio.

Estudio Contacto

Ubicaciones de estudio

  • Pakistán
    • Punjab Province
      • Lahore, Punjab Province, Pakistán, 59300
        • Ittefaq Hospital and Ghurki Trust Hospital
        • Contacto:
        • Investigador principal:
          • Ayesha Sehar, MS-CPPT

Criterios de participación

Los investigadores buscan personas que se ajusten a una determinada descripción, denominada criterio de elegibilidad. Algunos ejemplos de estos criterios son el estado de salud general de una persona o tratamientos previos.

Criterio de elegibilidad

Edades elegibles para estudiar

  • Adulto

Acepta Voluntarios Saludables

No

Descripción

Inclusion Criteria:

  • Male and female patients diagnosed with asthma.
  • Age between 18 and 40 years.
  • Patients with mild to moderate asthma who are clinically stable.
  • Patients able to understand and follow breathing exercise instructions.
  • Patients willing to provide informed consent and participate in the study.

Exclusion Criteria:

  • Patients with severe or uncontrolled asthma.
  • Patients with acute asthma exacerbation during the study period.
  • Patients with other significant respiratory diseases (e.g., chronic obstructive pulmonary disease, pulmonary fibrosis).
  • Patients with severe cardiovascular, neurological, or musculoskeletal disorders that may interfere with participation.
  • Patients who are pregnant.
  • Patients unable to perform the breathing interventions or complete study assessments.
  • Patients participating in another structured respiratory rehabilitation or breathing exercise program.

Plan de estudios

Esta sección proporciona detalles del plan de estudio, incluido cómo está diseñado el estudio y qué mide el estudio.

¿Cómo está diseñado el estudio?

Detalles de diseño

  • Propósito principal: Tratamiento
  • Asignación: Aleatorizado
  • Modelo Intervencionista: Asignación paralela
  • Enmascaramiento: Ninguno (etiqueta abierta)

Armas e Intervenciones

Grupo de participantes/brazo
Intervención / Tratamiento
Experimental: Box Breathing Group A
Participants assigned to this arm received standardized baseline respiratory care followed by Box Breathing training. The Box Breathing technique consisted of inhaling for 4 seconds, holding the breath for 4 seconds, exhaling for 4 seconds, and holding the breath again for 4 seconds. The intervention was performed for 20 minutes per session, three sessions per week, for eight weeks. Short rest periods were provided as needed during the intervention.
Conductual: Box Breathing
Participants assigned to the Box Breathing intervention received a structured breathing exercise protocol following standardized baseline respiratory care. The Box Breathing technique consisted of inhalation for 4 seconds, breath holding for 4 seconds, exhalation for 4 seconds, and a second breath hold for 4 seconds (4-4-4-4 pattern). The intervention was administered for 20 minutes per session, three sessions per week, for eight weeks. Short rest periods were permitted after every 5-6 breathing cycles as needed. The intervention was performed in a quiet environment and aimed to improve respiratory control, reduce dyspnea, enhance ventilatory efficiency, and promote autonomic regulation.
Experimental: Rhythmic Breathing Group
Participants assigned to this arm received standardized baseline respiratory care followed by Rhythmic Breathing training. The Rhythmic Breathing technique consisted of a controlled breathing pattern using a 4:6 ratio, with inhalation through the nose for 4 seconds and exhalation through the mouth for 6 seconds. The intervention was performed for 20 minutes per session, three sessions per week, for eight weeks. Short rest periods were provided as needed during the intervention.
Conductual: Rhythmic Breathing
Participants assigned to the Rhythmic Breathing intervention received a structured breathing exercise protocol following standardized baseline respiratory care. The Rhythmic Breathing technique consisted of a controlled breathing pattern using a 4:6 ratio, with inhalation through the nose for 4 seconds and exhalation through the mouth for 6 seconds. The intervention was administered for 20 minutes per session, three sessions per week, for eight weeks. Short rest periods were provided every 6-7 minutes as needed. The intervention was designed to promote respiratory efficiency, improve autonomic balance, reduce dyspnea, and enhance pulmonary function and sleep quality.

¿Qué mide el estudio?

Medidas de resultado primarias

Medida de resultado
Medida Descripción
Periodo de tiempo
Dyspnea Severity
Periodo de tiempo: Baseline and 8 weeks (post-intervention)
Dyspnea severity will be assessed using the Modified Borg Scale, a numerical rating scale ranging from 0 to 10, where higher scores indicate greater perceived breathlessness.
Baseline and 8 weeks (post-intervention)

Medidas de resultado secundarias

Medida de resultado
Medida Descripción
Periodo de tiempo
Pulmonary Function (Forced Expiratory Volume in 1 Second [FEV₁])
Periodo de tiempo: Baseline and 8 weeks (post-intervention)
Pulmonary function will be assessed using spirometry. Forced Expiratory Volume in 1 second (FEV₁) will be used to evaluate changes in lung function following the intervention.
Baseline and 8 weeks (post-intervention)
Sleep Quality
Periodo de tiempo: Baseline and 8 weeks (post-intervention)
Sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI), a validated questionnaire measuring subjective sleep quality over the previous month. Lower scores indicate better sleep quality.
Baseline and 8 weeks (post-intervention)

Colaboradores e Investigadores

Aquí es donde encontrará personas y organizaciones involucradas en este estudio.

Patrocinador

Riphah International University

Investigadores

  • Investigador principal: Humera Ayub, MS-CPPT, Riphah International University

Fechas de registro del estudio

Estas fechas rastrean el progreso del registro del estudio y los envíos de resultados resumidos a ClinicalTrials.gov. Los registros del estudio y los resultados informados son revisados ​​por la Biblioteca Nacional de Medicina (NLM) para asegurarse de que cumplan con los estándares de control de calidad específicos antes de publicarlos en el sitio web público.

Fechas importantes del estudio

Inicio del estudio (Estimado)

1 de julio de 2026

Finalización primaria (Estimado)

10 de diciembre de 2026

Finalización del estudio (Estimado)

10 de diciembre de 2026

Fechas de registro del estudio

Enviado por primera vez

17 de julio de 2026

Primero enviado que cumplió con los criterios de control de calidad

17 de julio de 2026

Publicado por primera vez (Actual)

21 de julio de 2026

Actualizaciones de registros de estudio

Última actualización publicada (Actual)

21 de julio de 2026

Última actualización enviada que cumplió con los criterios de control de calidad

17 de julio de 2026

Última verificación

1 de julio de 2026

Más información

Términos relacionados con este estudio

Palabras clave

Términos MeSH relevantes adicionales

Otros números de identificación del estudio

  • REC/RCR & AHS/25/0315

Plan de datos de participantes individuales (IPD)

¿Planea compartir datos de participantes individuales (IPD)?

NO

Descripción del plan IPD

Individual participant data (IPD) collected during this study will not be made publicly available. The decision not to share IPD is based on the need to protect participant privacy and confidentiality, as the informed consent process did not include provisions for public data sharing. Only aggregate and de-identified study findings will be reported and published.

Información sobre medicamentos y dispositivos, documentos del estudio

Estudia un producto farmacéutico regulado por la FDA de EE. UU.

No

Estudia un producto de dispositivo regulado por la FDA de EE. UU.

No

Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .

Suscribir