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- Registro de ensayos clínicos de EE. UU.
- Ensayo clínico NCT07932860
Comparison Between Ultrasound Guided Pericapsular Nerve Block And Suprainguinal Fascia Iliaca Nerve Block in Hip Surgery (PENG block)
Hip fracture is a common orthopedic emergency in the elderly, and it is associated with significant morbidity and mortality. Surgical reduction and fixation are the definitive treatment in most patients, effective perioperative analgesia that minimizes the need for opioids and related adverse effects (such as delirium) is essential in this patient population.
In this study we are going to compare the effects of ultrasound guided pericapsular nerve group (PENG) block and suprainguinal fascia iliaca compartment block (FICB) on postoperative analgesia and quadriceps strength following total hip arthroplasty.
Descripción general del estudio
Estado
Condiciones
Intervención / Tratamiento
Descripción detallada
Total hip replacements (THRs) are quite successful surgery for many end-stage hip diseases in terms of pain relief and functional recovery (Lindberg-larsen M et al,2020). However, THR are associated with severe perioperative pain which prolongs length of hospitalization and increases the morbidity and medical cost (Guarino AJ et al,2019). Adequate pain management is crucial for improving the satisfaction of patients and clinical outcomes. Numerous strategies have been implemented to reduce postoperative pain following THR including local infiltration analgesia, epidural analgesia, intravenous non-steroidal anti-inflammatory agents and peripheral nerve block. (Kuchalik J et al,2017).
So, multimodal analgesia has been extensively used in perioperative period of THR (Berninger MT etal, 2019).
One of the regional anesthesia options for hip surgery is the fascia iliaca compartment block (FICB) that affects nerves important for hip innervation and sensory innervation of the thigh - femoral, obturator and lateral femoral cutaneous nerve.(Standring S,2015). FICB can be easily performed and is often a good solution for management of hip fractures in emergency departments. Its use reduces morphine pre-operative requirement for patients with femoral neck fractures and can also be indicated for hip arthroplasty, hip arthroscopy and burn management of the region (Madabushi R, 2016). A suprainguinal FICB produces a more complete sensory block of the medial, anterior and lateral region of the thigh when compared to infra-inguinal FICB. Additionally,supra-inguinal FICB leads to a more consistent spread in the cranial direction, thus spreading the anesthetic more consistently towards the lumbar plexus and three targeted nerves. So,the supra-inguinal approach has a superior postoperative analgesic efficacy compared to infra-inguinal approach along with significantly less morphine consumption in the first 24(Garner M,2017).
The pericapsular nerve group (PENG) block, which targets sensory branches of the obturator, accessory obturator, and femoral nerves in the anterior capsule of the hip, has been proposed as an effective method to treat pain associated with hip fractures and total hip arthroplasty(THA)(Giron-Arango L,2018). The PENG block provides coverage of the sensory nerves supplying the anterior hip while sparing motor blockade of the quadriceps; a known complication of fascia iliaca and femoral blocks (Tran J,2019).
PENG block has potential advantages over traditional forms of regional analgesia for pain originating from the hip, such as femoral nerve or fascia iliaca blocks. One of these potential advantages include a wider and more complete coverage of sensory nerves innervating the hip, leading to more effective regional analgesia with the potential to reduce postoperative pain,increase patient satisfaction and allow early mobilization(Bartels K,2016).
Tipo de estudio
Inscripción (Estimado)
Fase
- No aplica
Contactos y Ubicaciones
Estudio Contacto
- Nombre: dalia tarek elshahawy, MSC
- Número de teléfono: +201062128018
- Correo electrónico: dr.daliaelshahawy@gmail.com
Ubicaciones de estudio
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Cairo Governorate
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Cairo, Cairo Governorate, Egipto, 11211
- Reclutamiento
- Ain Shams University
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Contacto:
- dalia tarek elshahawy, msc
- Número de teléfono: +201062128018
- Correo electrónico: dr.dalilaelshahawy@gmail.com
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Criterios de participación
Criterio de elegibilidad
Edades elegibles para estudiar
Acepta Voluntarios Saludables
Géneros elegibles para el estudio
Descripción
Inclusion Criteria:
- Patients scheduled for hip surgeries.
- Age: patients aged ≥ 18 years old from both sexes.
- Patients American Society of Anesthesiologists physical status (ASA) class I-III.
Exclusion Criteria:
- - Refusal of procedure or participation in the study.
- Patients suffering from allergy to local anestheics.
- Patients with coagulation disorders or those on anticoagulant medication.
- Infection in punctured site.
- Classified as either American Society of Anesthesiologists (ASA) class IV-V
- Patients suffering from cardiac condition,dementia or cognitive impairment, liver failure, renal insufficiency and pre-existing neurologic deficits.
Plan de estudios
¿Cómo está diseñado el estudio?
Detalles de diseño
- Propósito principal: Tratamiento
- Asignación: Aleatorizado
- Modelo Intervencionista: Asignación paralela
- Enmascaramiento: Único
Armas e Intervenciones
Grupo de participantes/brazo |
Intervención / Tratamiento |
|---|---|
|
Experimental: group P
patients receiving Peng block. |
patients receiving Peng block. |
|
Experimental: Group F
patients receiving suprainguinal Fascia iliaca block. |
patients receiving suprainguinal Fascia iliaca block |
¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
|
pain score(VAS score)
Periodo de tiempo: 24 hour
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The primary outcome measure was pain scores(VAS score) from 0(no pain) till 10 severe pain |
24 hour
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Colaboradores e Investigadores
Patrocinador
Publicaciones y enlaces útiles
Fechas de registro del estudio
Fechas importantes del estudio
Inicio del estudio (Actual)
Finalización primaria (Estimado)
Finalización del estudio (Estimado)
Fechas de registro del estudio
Enviado por primera vez
Primero enviado que cumplió con los criterios de control de calidad
Publicado por primera vez (Actual)
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
Última actualización enviada que cumplió con los criterios de control de calidad
Última verificación
Más información
Términos relacionados con este estudio
Otros números de identificación del estudio
- Hip Surgery Block
Información sobre medicamentos y dispositivos, documentos del estudio
Estudia un producto farmacéutico regulado por la FDA de EE. UU.
Estudia un producto de dispositivo regulado por la FDA de EE. UU.
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