Long-term Quality of Life Among Survivors of Sepsis in China Assessed by EQ-5D
Long-term Outcome Among Survivors of Sepsis in China Assessed by EQ-5D
Aperçu de l'étude
Statut
Les conditions
Description détaillée
Sepsis is a clinical syndrome in which the body's host response to uncontrolled infection leads to life-threatening organ dysfunction. In recent years, with the continuous improvement of the early diagnosis ability of sepsis, the deepening of the understanding of pathophysiology, and the continuous updating of treatment, the hospital mortality rate of sepsis has decreased significantly. However, studies have shown that the prevalence of sepsis is still increasing year by year, and the number of deaths due to sepsis is increasing. Sepsis is the main cause of death in ICU patients.
Although the mortality rate of patients with sepsis is significantly reduced, the increasing survival of patients with long-term outcome is not satisfied. All studies have shown that patients with sepsis have a high long-term mortality, and the long-term physiological, psychological, and cognitive function levels are reduced, which increases the economic burden and mental burden of the family and society. The increasing number of discharges has been considered a potential public health threat. In recent years, more and more researchers begin to pay attention to the long-term outcome of sepsis survivors. But compared with other acute or severe diseases, such as stroke, cancer, sepsis survivors has not been paid enough attention.
Therefore, all stages of treatment and rehabilitation of sepsis require extensive social attention. Continuous research and input are needed to explore predicting factors and effective interventions to improve the outcome and help patients and their families return to normal life,to reduce the social burden.
Type d'étude
Inscription (Réel)
Contacts et emplacements
Lieux d'étude
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Jiangsu
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Nanjing, Jiangsu, Chine, 210009
- Zhongda Hospital, Southeast University
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Critères de participation
Critère d'éligibilité
Âges éligibles pour étudier
- Enfant
- Adulte
- Adulte plus âgé
Accepte les volontaires sains
Sexes éligibles pour l'étude
Méthode d'échantillonnage
Population étudiée
La description
Inclusion Criteria:
- survivors in the prior study (epidemiology survey of Chinese sepsis patients)
Exclusion Criteria:
- : patients who are unwilling to answer or lose their interviews
Plan d'étude
Comment l'étude est-elle conçue ?
Détails de conception
Que mesure l'étude ?
Principaux critères de jugement
Mesure des résultats |
Description de la mesure |
Délai |
|---|---|---|
|
2-year mortality
Délai: 2 year
|
sepsis survivors will be followed up for 2-years
|
2 year
|
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2-year readmission rate
Délai: 2 year
|
sepsis survivors will be followed up for 2-years
|
2 year
|
|
mobility of sepsis survivors
Délai: 2 year
|
one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
|
2 year
|
|
self-care of sepsis survivors
Délai: 2 year
|
one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
|
2 year
|
|
usual activities of sepsis survivors
Délai: 2 year
|
one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
|
2 year
|
|
discomfort or pain of sepsis survivors
Délai: 2 year
|
one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
|
2 year
|
|
depression or anxiety of sepsis survivors
Délai: 2 year
|
one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
|
2 year
|
|
the ability to judge and memory of sepsis survivors
Délai: 2 year
|
It is scored by family or by yourself during telephone follow-up and is used to evaluate the quaity of life of sepsis survivors.
|
2 year
|
Mesures de résultats secondaires
Mesure des résultats |
Description de la mesure |
Délai |
|---|---|---|
|
influencing factors
Délai: 2 year
|
explore the relationship between the outcome of sepsis survivors and clinical characteristics.The clinical characteristics is collected from Clinical case system,to explore their relationship with two-year survival, two-year quality of life of sepsis survivors.
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2 year
|
Collaborateurs et enquêteurs
Parrainer
Les enquêteurs
- Directeur d'études: Yang Yi, Ph.D., Zhongda hospital
Dates d'enregistrement des études
Dates principales de l'étude
Début de l'étude (Réel)
Achèvement primaire (Réel)
Achèvement de l'étude (Réel)
Dates d'inscription aux études
Première soumission
Première soumission répondant aux critères de contrôle qualité
Première publication (Réel)
Mises à jour des dossiers d'étude
Dernière mise à jour publiée (Réel)
Dernière mise à jour soumise répondant aux critères de contrôle qualité
Dernière vérification
Plus d'information
Termes liés à cette étude
Termes MeSH pertinents supplémentaires
Autres numéros d'identification d'étude
- sepsis long-term outcome
Informations sur les médicaments et les dispositifs, documents d'étude
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