Long-term Quality of Life Among Survivors of Sepsis in China Assessed by EQ-5D
Long-term Outcome Among Survivors of Sepsis in China Assessed by EQ-5D
Studienübersicht
Status
Bedingungen
Detaillierte Beschreibung
Sepsis is a clinical syndrome in which the body's host response to uncontrolled infection leads to life-threatening organ dysfunction. In recent years, with the continuous improvement of the early diagnosis ability of sepsis, the deepening of the understanding of pathophysiology, and the continuous updating of treatment, the hospital mortality rate of sepsis has decreased significantly. However, studies have shown that the prevalence of sepsis is still increasing year by year, and the number of deaths due to sepsis is increasing. Sepsis is the main cause of death in ICU patients.
Although the mortality rate of patients with sepsis is significantly reduced, the increasing survival of patients with long-term outcome is not satisfied. All studies have shown that patients with sepsis have a high long-term mortality, and the long-term physiological, psychological, and cognitive function levels are reduced, which increases the economic burden and mental burden of the family and society. The increasing number of discharges has been considered a potential public health threat. In recent years, more and more researchers begin to pay attention to the long-term outcome of sepsis survivors. But compared with other acute or severe diseases, such as stroke, cancer, sepsis survivors has not been paid enough attention.
Therefore, all stages of treatment and rehabilitation of sepsis require extensive social attention. Continuous research and input are needed to explore predicting factors and effective interventions to improve the outcome and help patients and their families return to normal life,to reduce the social burden.
Studientyp
Einschreibung (Tatsächlich)
Kontakte und Standorte
Studienorte
-
-
Jiangsu
-
Nanjing, Jiangsu, China, 210009
- Zhongda Hospital, Southeast University
-
-
Teilnahmekriterien
Zulassungskriterien
Studienberechtigtes Alter
- Kind
- Erwachsene
- Älterer Erwachsener
Akzeptiert gesunde Freiwillige
Studienberechtigte Geschlechter
Probenahmeverfahren
Studienpopulation
Beschreibung
Inclusion Criteria:
- survivors in the prior study (epidemiology survey of Chinese sepsis patients)
Exclusion Criteria:
- : patients who are unwilling to answer or lose their interviews
Studienplan
Wie ist die Studie aufgebaut?
Designdetails
Was misst die Studie?
Primäre Ergebnismessungen
Ergebnis Maßnahme |
Maßnahmenbeschreibung |
Zeitfenster |
|---|---|---|
|
2-year mortality
Zeitfenster: 2 year
|
sepsis survivors will be followed up for 2-years
|
2 year
|
|
2-year readmission rate
Zeitfenster: 2 year
|
sepsis survivors will be followed up for 2-years
|
2 year
|
|
mobility of sepsis survivors
Zeitfenster: 2 year
|
one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
|
2 year
|
|
self-care of sepsis survivors
Zeitfenster: 2 year
|
one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
|
2 year
|
|
usual activities of sepsis survivors
Zeitfenster: 2 year
|
one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
|
2 year
|
|
discomfort or pain of sepsis survivors
Zeitfenster: 2 year
|
one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
|
2 year
|
|
depression or anxiety of sepsis survivors
Zeitfenster: 2 year
|
one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
|
2 year
|
|
the ability to judge and memory of sepsis survivors
Zeitfenster: 2 year
|
It is scored by family or by yourself during telephone follow-up and is used to evaluate the quaity of life of sepsis survivors.
|
2 year
|
Sekundäre Ergebnismessungen
Ergebnis Maßnahme |
Maßnahmenbeschreibung |
Zeitfenster |
|---|---|---|
|
influencing factors
Zeitfenster: 2 year
|
explore the relationship between the outcome of sepsis survivors and clinical characteristics.The clinical characteristics is collected from Clinical case system,to explore their relationship with two-year survival, two-year quality of life of sepsis survivors.
|
2 year
|
Mitarbeiter und Ermittler
Sponsor
Ermittler
- Studienleiter: Yang Yi, Ph.D., Zhongda Hospital
Studienaufzeichnungsdaten
Haupttermine studieren
Studienbeginn (Tatsächlich)
Primärer Abschluss (Tatsächlich)
Studienabschluss (Tatsächlich)
Studienanmeldedaten
Zuerst eingereicht
Zuerst eingereicht, das die QC-Kriterien erfüllt hat
Zuerst gepostet (Tatsächlich)
Studienaufzeichnungsaktualisierungen
Letztes Update gepostet (Tatsächlich)
Letztes eingereichtes Update, das die QC-Kriterien erfüllt
Zuletzt verifiziert
Mehr Informationen
Begriffe im Zusammenhang mit dieser Studie
Zusätzliche relevante MeSH-Bedingungen
Andere Studien-ID-Nummern
- sepsis long-term outcome
Arzneimittel- und Geräteinformationen, Studienunterlagen
Studiert ein von der US-amerikanischen FDA reguliertes Arzneimittelprodukt
Studiert ein von der US-amerikanischen FDA reguliertes Geräteprodukt
Diese Informationen wurden ohne Änderungen direkt von der Website clinicaltrials.gov abgerufen. Wenn Sie Ihre Studiendaten ändern, entfernen oder aktualisieren möchten, wenden Sie sich bitte an register@clinicaltrials.gov. Sobald eine Änderung auf clinicaltrials.gov implementiert wird, wird diese automatisch auch auf unserer Website aktualisiert .
Klinische Studien zur Sepsis
-
University of California, San FranciscoNational Cancer Institute (NCI)RekrutierungSepsis | Sepsis, schwer | Sepsis und septischer Schock | Sepsis auf der Intensivstation | Sepsis, septischer Schock | Sepsis, schwere Sepsis und septischer Schock | Sepsis mit multipler Organdysfunktion (MOD) | Sepsis mit akuter OrgandysfunktionVereinigte Staaten
-
Assiut UniversityNoch keine RekrutierungSepsis-induzierte Myokarddysfunktion | Sepsis induzierte KardiomyopathieÄgypten
-
University of Kansas Medical CenterUniversity of KansasRekrutierungSepsis | Septischer Schock | Sepsis-Syndrom | Sepsis, schwer | Bakterielle Sepsis | Sepsis-BakterämieVereinigte Staaten
-
Jip GroenInBiomeRekrutierungMikrobielle Besiedlung | Neonatale Infektion | Neonatale Sepsis, früher Beginn | Mikrobielle Krankheit | Klinische Sepsis | Kultur-negative neonatale Sepsis | Neonatale Sepsis, später Beginn | Kulturpositive neonatale SepsisNiederlande
-
Karolinska InstitutetÖrebro University, SwedenAbgeschlossenSepsis | Sepsis-Syndrom | Sepsis, schwerSchweden
-
The University of QueenslandRoyal Brisbane and Women's HospitalUnbekannt
-
Ohio State UniversityAbgeschlossenSepsis, schwere Sepsis und septischer SchockVereinigte Staaten
-
Rennes University HospitalUnbekanntSchwere Sepsis oder septischer Schock
-
Beckman Coulter, Inc.Biomedical Advanced Research and Development AuthorityAnmeldung auf EinladungSchwere Sepsis | Schwere Sepsis ohne septischen SchockVereinigte Staaten
-
Indonesia UniversityAbgeschlossenSchwere Sepsis mit septischem Schock | Schwere Sepsis ohne septischen SchockIndonesien