Long-term Quality of Life Among Survivors of Sepsis in China Assessed by EQ-5D
Long-term Outcome Among Survivors of Sepsis in China Assessed by EQ-5D
Descripción general del estudio
Estado
Condiciones
Descripción detallada
Sepsis is a clinical syndrome in which the body's host response to uncontrolled infection leads to life-threatening organ dysfunction. In recent years, with the continuous improvement of the early diagnosis ability of sepsis, the deepening of the understanding of pathophysiology, and the continuous updating of treatment, the hospital mortality rate of sepsis has decreased significantly. However, studies have shown that the prevalence of sepsis is still increasing year by year, and the number of deaths due to sepsis is increasing. Sepsis is the main cause of death in ICU patients.
Although the mortality rate of patients with sepsis is significantly reduced, the increasing survival of patients with long-term outcome is not satisfied. All studies have shown that patients with sepsis have a high long-term mortality, and the long-term physiological, psychological, and cognitive function levels are reduced, which increases the economic burden and mental burden of the family and society. The increasing number of discharges has been considered a potential public health threat. In recent years, more and more researchers begin to pay attention to the long-term outcome of sepsis survivors. But compared with other acute or severe diseases, such as stroke, cancer, sepsis survivors has not been paid enough attention.
Therefore, all stages of treatment and rehabilitation of sepsis require extensive social attention. Continuous research and input are needed to explore predicting factors and effective interventions to improve the outcome and help patients and their families return to normal life,to reduce the social burden.
Tipo de estudio
Inscripción (Actual)
Contactos y Ubicaciones
Ubicaciones de estudio
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Jiangsu
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Nanjing, Jiangsu, Porcelana, 210009
- Zhongda Hospital, Southeast University
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Criterios de participación
Criterio de elegibilidad
Edades elegibles para estudiar
- Niño
- Adulto
- Adulto Mayor
Acepta Voluntarios Saludables
Géneros elegibles para el estudio
Método de muestreo
Población de estudio
Descripción
Inclusion Criteria:
- survivors in the prior study (epidemiology survey of Chinese sepsis patients)
Exclusion Criteria:
- : patients who are unwilling to answer or lose their interviews
Plan de estudios
¿Cómo está diseñado el estudio?
Detalles de diseño
¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
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2-year mortality
Periodo de tiempo: 2 year
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sepsis survivors will be followed up for 2-years
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2 year
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2-year readmission rate
Periodo de tiempo: 2 year
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sepsis survivors will be followed up for 2-years
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2 year
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mobility of sepsis survivors
Periodo de tiempo: 2 year
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one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
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2 year
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self-care of sepsis survivors
Periodo de tiempo: 2 year
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one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
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2 year
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usual activities of sepsis survivors
Periodo de tiempo: 2 year
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one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
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2 year
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discomfort or pain of sepsis survivors
Periodo de tiempo: 2 year
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one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
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2 year
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depression or anxiety of sepsis survivors
Periodo de tiempo: 2 year
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one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors.
They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.
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2 year
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the ability to judge and memory of sepsis survivors
Periodo de tiempo: 2 year
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It is scored by family or by yourself during telephone follow-up and is used to evaluate the quaity of life of sepsis survivors.
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2 year
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Medidas de resultado secundarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
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influencing factors
Periodo de tiempo: 2 year
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explore the relationship between the outcome of sepsis survivors and clinical characteristics.The clinical characteristics is collected from Clinical case system,to explore their relationship with two-year survival, two-year quality of life of sepsis survivors.
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2 year
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Colaboradores e Investigadores
Patrocinador
Investigadores
- Director de estudio: Yang Yi, Ph.D., Zhongda Hospital
Fechas de registro del estudio
Fechas importantes del estudio
Inicio del estudio (Actual)
Finalización primaria (Actual)
Finalización del estudio (Actual)
Fechas de registro del estudio
Enviado por primera vez
Primero enviado que cumplió con los criterios de control de calidad
Publicado por primera vez (Actual)
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
Última actualización enviada que cumplió con los criterios de control de calidad
Última verificación
Más información
Términos relacionados con este estudio
Términos MeSH relevantes adicionales
Otros números de identificación del estudio
- sepsis long-term outcome
Información sobre medicamentos y dispositivos, documentos del estudio
Estudia un producto farmacéutico regulado por la FDA de EE. UU.
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Ensayos clínicos sobre Septicemia
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University of California, San FranciscoNational Cancer Institute (NCI)ReclutamientoSepticemia | Sepsis, Severa | Sepsis y Choque Séptico | Sepsis en Unidad de Cuidados Intensivos | Sepsis, Choque Séptico | Sepsis, Sepsis Severa y Shock Séptico | Sepsis con disfunción orgánica múltiple (MOD) | Sepsis con disfunción orgánica agudaEstados Unidos
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Assiut UniversityAún no reclutandoDisfunción miocárdica inducida por sepsis | Miocardiopatía inducida por sepsisEgipto
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University of Kansas Medical CenterUniversity of KansasReclutamientoSepticemia | Shock séptico | Síndrome de sepsis | Sepsis, Severa | Sepsis bacteriana | Sepsis BacteriemiaEstados Unidos
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Jip GroenInBiomeReclutamientoColonización Microbiana | Infeccion Neonatal | Sepsis Neonatal, Inicio Temprano | Enfermedad microbiana | Sepsis clínica | Sepsis neonatal con cultivo negativo | Sepsis Neonatal, Inicio Tardío | Sepsis neonatal con cultivo positivoPaíses Bajos
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Indonesia UniversityTerminadoImpacto del tratamiento con heparina no fraccionada en dosis bajas sobre la inflamación en la sepsisSepsis severa con shock séptico | Sepsis severa sin shock sépticoIndonesia
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London Health Sciences Centre Research Institute...Aún no reclutando
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Carol Davila University of Medicine and PharmacyReclutamiento
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Assiut UniversityAún no reclutandoSepsis en Pacientes de UrgenciasEgipto
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Firat UniversityTerminadoSepsis - para Reducir la Mortalidad en la Unidad de Cuidados Intensivos | Biomarcador de Sepsis | Regulación Molecular a la Baja de Fenixina-14Turquía (Türkiye)
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The Fourth Affiliated Hospital of Zhejiang University...Aún no reclutando