Changes of Ocular Structures After Hemodialysis in Patients With Chronic Kidney Diseases
調査の概要
詳細な説明
Subjects: patients with ESRD undergoing hemodialysis at the Dialysis Center of Hanyang Guri Hospital
Ocular parameters: visual acuity, intraocular pressure, axial length, OCT Other systemic parameters: body weight, ultrafiltration volume, and systolic/diastolic blood pressure
All measurements were performed near the dialysis center. Measurements were performed on Monday (for patients who underwent dialysis sessions on Monday, Wednesday, and Friday) or Tuesday (for patients who underwent dialysis sessions on Tuesday, Thursday, and Saturday.
All parameters were measured before and after the hemodialysis.
研究の種類
入学 (実際)
参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
サンプリング方法
調査対象母集団
説明
Inclusion Criteria:
- 1) patients who are regularly dialyzed in our dialysis room to participate in the study
- 2) patients who agree with our study protocol
- 3) patients who have unstable general condition
Exclusion Criteria:
- 1) previous intraocular surgery, (2) baseline IOP greater than 22 mmHg, (3) presence of glaucomatous optic disc changes including excavation, thinning, or notching of the neuroretinal rim, (4) axial length greater than 26 mm, and (5) combined macular and retinal diseases such as central serous chorioretinopathy and age-related macular degeneration, except diabetic retinopathy.
研究計画
研究はどのように設計されていますか?
デザインの詳細
コホートと介入
グループ/コホート |
介入・治療 |
---|---|
patients with chronic kidney diseases
patients with end stage retinal disease undergoing hemodialysis underwent various ophthalmologic exams before and after hemodialysis.
|
ophthalmologic exams such as vision, intraocular pressure, axial length and optical coherence tomography
|
この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
changes of retinal and choroidal thickness after hemodialysis
時間枠:immediately (within 10 minutes) before and after hemodialysis
|
retinal & choroidal thickness on OCT
|
immediately (within 10 minutes) before and after hemodialysis
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
changes of foveal vascular density using optical coherence tomography-angiography (OCTA) after hemodialysis
時間枠:immediately (within 10 minutes) before and after hemodialysis
|
vessel density on OCTA
|
immediately (within 10 minutes) before and after hemodialysis
|
the effect of hemodialysis (HD) on anterior chamber angle by anterior segment optical coherence
時間枠:immediately (within 10 minutes) before and after hemodialysis
|
intraocular pressure, retinal thickness, anterior chamber angle
|
immediately (within 10 minutes) before and after hemodialysis
|
協力者と研究者
スポンサー
捜査官
- スタディチェア:Heeyoon Cho, MD、Hanyang University
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (実際)
研究の完了 (実際)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
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