Changes of Ocular Structures After Hemodialysis in Patients With Chronic Kidney Diseases
研究概览
详细说明
Subjects: patients with ESRD undergoing hemodialysis at the Dialysis Center of Hanyang Guri Hospital
Ocular parameters: visual acuity, intraocular pressure, axial length, OCT Other systemic parameters: body weight, ultrafiltration volume, and systolic/diastolic blood pressure
All measurements were performed near the dialysis center. Measurements were performed on Monday (for patients who underwent dialysis sessions on Monday, Wednesday, and Friday) or Tuesday (for patients who underwent dialysis sessions on Tuesday, Thursday, and Saturday.
All parameters were measured before and after the hemodialysis.
研究类型
注册 (实际的)
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- 1) patients who are regularly dialyzed in our dialysis room to participate in the study
- 2) patients who agree with our study protocol
- 3) patients who have unstable general condition
Exclusion Criteria:
- 1) previous intraocular surgery, (2) baseline IOP greater than 22 mmHg, (3) presence of glaucomatous optic disc changes including excavation, thinning, or notching of the neuroretinal rim, (4) axial length greater than 26 mm, and (5) combined macular and retinal diseases such as central serous chorioretinopathy and age-related macular degeneration, except diabetic retinopathy.
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
|
patients with chronic kidney diseases
patients with end stage retinal disease undergoing hemodialysis underwent various ophthalmologic exams before and after hemodialysis.
|
ophthalmologic exams such as vision, intraocular pressure, axial length and optical coherence tomography
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
changes of retinal and choroidal thickness after hemodialysis
大体时间：immediately (within 10 minutes) before and after hemodialysis
|
retinal & choroidal thickness on OCT
|
immediately (within 10 minutes) before and after hemodialysis
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
changes of foveal vascular density using optical coherence tomography-angiography (OCTA) after hemodialysis
大体时间：immediately (within 10 minutes) before and after hemodialysis
|
vessel density on OCTA
|
immediately (within 10 minutes) before and after hemodialysis
|
|
the effect of hemodialysis (HD) on anterior chamber angle by anterior segment optical coherence
大体时间：immediately (within 10 minutes) before and after hemodialysis
|
intraocular pressure, retinal thickness, anterior chamber angle
|
immediately (within 10 minutes) before and after hemodialysis
|
合作者和调查者
调查人员
- 学习椅：Heeyoon Cho, MD、Hanyang University
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
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-
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