Home-Based Exercise Programs for Fall Prevention in Parkinson Disease
2026年8月14日 更新者：Selim Mahmut GÜNAY、Uludag University
Effectiveness of Fall-Preventive Home Exercise Programs in Patients With Parkinson Disease: A Randomized Controlled Trial
Falls are common in patients with Parkinson disease and may lead to reduced mobility, fear of falling, loss of independence, and injury. Exercise-based rehabilitation programs may help improve balance, gait, and physical performance in this population.
This randomized controlled trial aims to compare the effectiveness of two home-based exercise programs in patients with Parkinson disease: the Otago Exercise Program and a structured home exercise program. Participants will be randomly assigned to one of two groups. Both groups will receive exercise education and will perform their assigned home exercise program for 6 weeks.
Participants will be evaluated at baseline, at week 3, and at the end of week 6. The study will assess fall-related outcomes, freezing of gait, functional mobility, gait parameters, postural control, and physical performance. The results may help determine which home-based exercise approach is more effective for reducing fall risk and improving functional outcomes in patients with Parkinson disease.
調査の概要
状態
完了
研究の種類
介入
入学 (実際)
28
段階
- 適用できない
連絡先と場所
このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。
研究場所
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Antakya
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Hatay、Antakya、トルコ（Türkiye）
- Hatay Mustafa Kemal University
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参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
- 大人
- 高齢者
健康ボランティアの受け入れ
いいえ
説明
Inclusion Criteria:
- Diagnosis of Parkinson disease confirmed by a neurologist
- Hoehn and Yahr stage 3 or 4 Parkinson disease
- Diagnosis of Parkinson disease for at least 5 years
- Willingness to participate in the study and provide written informed consent
- Ability to walk independently or with minimal assistance
- Mini-Mental State Examination score >24
Exclusion Criteria:
- Balance or gait impairment due to causes other than Parkinson disease, such as severe orthopedic problems or another neurological disease
- Red flags suggestive of Parkinson-plus syndromes, such as symmetric onset, early falls, early-onset dementia, or gaze palsy
- History of serious fall-related injury or surgery within the last 6 months
- Any additional health condition that would prevent participation in the exercise program during the study period
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：処理
- 割り当て：ランダム化
- 介入モデル：並列代入
- マスキング：独身
武器と介入
参加者グループ / アーム |
介入・治療 |
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実験的：Otago Home Exercise Program
Participants in this arm will receive the Otago Home Exercise Program.
The program includes home-based strengthening, static balance, and dynamic balance exercises designed to improve lower extremity muscle strength, balance, functional mobility, and fall-related outcomes.
Participants will perform the exercises 3 times per week for 6 weeks, with each session lasting approximately 40 minutes.
The exercise program will be reviewed and progressed at week 3 according to the participant's functional status.
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nce exercises designed to improve lower extremity muscle strength, balance, functional mobility, and fall-related outcomes.
Participants will perform the program 3 times per week for 6 weeks, with each session lasting approximately 40 minutes.
The program will be reviewed and progressed at week 3.
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アクティブコンパレータ：Structured Home Exercise Program
Participants in this arm will receive a structured home exercise program.
The program includes spinal stabilization exercises and stretching and strengthening exercises targeting the ankle plantar flexor and dorsiflexor muscles, quadriceps, lumbar extensor muscles, pectoral muscles, and hamstring muscles.
Participants will perform the exercises 3 times per week for 6 weeks, with each session lasting approximately 40 minutes.
The exercise program will be reviewed and progressed at week 3 according to the participant's functional status.
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The structured home exercise program is a home-based exercise intervention including spinal stabilization exercises and stretching and strengthening exercises targeting the ankle plantar flexor and dorsiflexor muscles, quadriceps, lumbar extensor muscles, pectoral muscles, and hamstring muscles.
Participants will perform the program 3 times per week for 6 weeks, with each session lasting approximately 40 minutes.
The program will be reviewed and progressed at week 3.
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この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Freezing of Gait Questionnaire (FOGQ)
時間枠：Baseline, week 3, and week 6
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Freezing of gait will be assessed using the Freezing of Gait Questionnaire (FOGQ).
The FOGQ evaluates the severity of freezing episodes and their impact on walking performance in patients with Parkinson disease.
The total score ranges from 0 to 24.
Higher scores indicate more severe freezing of gait and worse walking performance.
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Baseline, week 3, and week 6
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二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Falls Efficacy Scale
時間枠：Baseline, week 3, and week 6
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Fall-related self-efficacy and fear of falling will be assessed using the Falls Efficacy Scale.
The scale evaluates the participant's confidence in performing daily activities without falling.
Scores range from 10 to 100, with lower scores indicating greater fear of falling and higher scores indicating lower fear of falling.
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Baseline, week 3, and week 6
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Timed Up and Go Test
時間枠：Baseline, week 3, and week 6
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r, walk a short distance, turn, walk back, and sit down.
The time required to complete the test will be recorded in seconds, with longer times indicating poorer functional mobility.
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Baseline, week 3, and week 6
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Functional Reach Test
時間枠：Baseline, week 3, and week 6
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The Functional Reach Test will be used to assess dynamic balance and postural control.
The maximum distance the participant can reach forward while standing without losing balance will be recorded in centimeters.
Greater reach distance indicates better functional balance.
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Baseline, week 3, and week 6
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Sit-to-Stand Test
時間枠：Baseline, week 3, and week 6
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The sit-to-stand task will be used to assess functional lower extremity performance and postural control during transition from sitting to standing.
The time required to complete the movement will be recorded in seconds using video-based analysis.
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Baseline, week 3, and week 6
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Gait Initiation Time
時間枠：Baseline, week 3, and week 6
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Gait initiation time will be assessed using video-based kinematic analysis.
The time from the auditory cue to the initiation of the first step will be recorded in seconds.
Longer times indicate impaired gait initiation.
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Baseline, week 3, and week 6
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協力者と研究者
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スポンサー
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (実際)
2026年2月8日
一次修了 (実際)
2026年7月1日
研究の完了 (実際)
2026年8月1日
試験登録日
最初に提出
2026年5月10日
QC基準を満たした最初の提出物
2026年5月10日
最初の投稿 (実際)
2026年5月15日
学習記録の更新
投稿された最後の更新 (実際)
2026年8月18日
QC基準を満たした最後の更新が送信されました
2026年8月14日
最終確認日
2026年8月1日
詳しくは
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。