Home-Based Exercise Programs for Fall Prevention in Parkinson Disease
14. august 2026 oppdatert av: Selim Mahmut GÜNAY, Uludag University
Effectiveness of Fall-Preventive Home Exercise Programs in Patients With Parkinson Disease: A Randomized Controlled Trial
Falls are common in patients with Parkinson disease and may lead to reduced mobility, fear of falling, loss of independence, and injury. Exercise-based rehabilitation programs may help improve balance, gait, and physical performance in this population.
This randomized controlled trial aims to compare the effectiveness of two home-based exercise programs in patients with Parkinson disease: the Otago Exercise Program and a structured home exercise program. Participants will be randomly assigned to one of two groups. Both groups will receive exercise education and will perform their assigned home exercise program for 6 weeks.
Participants will be evaluated at baseline, at week 3, and at the end of week 6. The study will assess fall-related outcomes, freezing of gait, functional mobility, gait parameters, postural control, and physical performance. The results may help determine which home-based exercise approach is more effective for reducing fall risk and improving functional outcomes in patients with Parkinson disease.
Studieoversikt
Status
Fullført
Intervensjon / Behandling
Studietype
Intervensjonell
Registrering (Faktiske)
28
Fase
- Ikke aktuelt
Kontakter og plasseringer
Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.
Studiesteder
-
-
Antakya
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Hatay, Antakya, Tyrkia (Türkiye)
- Hatay Mustafa Kemal University
-
-
Deltakelseskriterier
Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.
Kvalifikasjonskriterier
Alder som er kvalifisert for studier
- Voksen
- Eldre voksen
Tar imot friske frivillige
Nei
Beskrivelse
Inclusion Criteria:
- Diagnosis of Parkinson disease confirmed by a neurologist
- Hoehn and Yahr stage 3 or 4 Parkinson disease
- Diagnosis of Parkinson disease for at least 5 years
- Willingness to participate in the study and provide written informed consent
- Ability to walk independently or with minimal assistance
- Mini-Mental State Examination score >24
Exclusion Criteria:
- Balance or gait impairment due to causes other than Parkinson disease, such as severe orthopedic problems or another neurological disease
- Red flags suggestive of Parkinson-plus syndromes, such as symmetric onset, early falls, early-onset dementia, or gaze palsy
- History of serious fall-related injury or surgery within the last 6 months
- Any additional health condition that would prevent participation in the exercise program during the study period
Studieplan
Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.
Hvordan er studiet utformet?
Designdetaljer
- Primært formål: Behandling
- Tildeling: Randomisert
- Intervensjonsmodell: Parallell tildeling
- Masking: Enkelt
Våpen og intervensjoner
Deltakergruppe / Arm |
Intervensjon / Behandling |
|---|---|
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Eksperimentell: Otago Home Exercise Program
Participants in this arm will receive the Otago Home Exercise Program.
The program includes home-based strengthening, static balance, and dynamic balance exercises designed to improve lower extremity muscle strength, balance, functional mobility, and fall-related outcomes.
Participants will perform the exercises 3 times per week for 6 weeks, with each session lasting approximately 40 minutes.
The exercise program will be reviewed and progressed at week 3 according to the participant's functional status.
|
nce exercises designed to improve lower extremity muscle strength, balance, functional mobility, and fall-related outcomes.
Participants will perform the program 3 times per week for 6 weeks, with each session lasting approximately 40 minutes.
The program will be reviewed and progressed at week 3.
|
|
Aktiv komparator: Structured Home Exercise Program
Participants in this arm will receive a structured home exercise program.
The program includes spinal stabilization exercises and stretching and strengthening exercises targeting the ankle plantar flexor and dorsiflexor muscles, quadriceps, lumbar extensor muscles, pectoral muscles, and hamstring muscles.
Participants will perform the exercises 3 times per week for 6 weeks, with each session lasting approximately 40 minutes.
The exercise program will be reviewed and progressed at week 3 according to the participant's functional status.
|
The structured home exercise program is a home-based exercise intervention including spinal stabilization exercises and stretching and strengthening exercises targeting the ankle plantar flexor and dorsiflexor muscles, quadriceps, lumbar extensor muscles, pectoral muscles, and hamstring muscles.
Participants will perform the program 3 times per week for 6 weeks, with each session lasting approximately 40 minutes.
The program will be reviewed and progressed at week 3.
|
Hva måler studien?
Primære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
|---|---|---|
|
Freezing of Gait Questionnaire (FOGQ)
Tidsramme: Baseline, week 3, and week 6
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Freezing of gait will be assessed using the Freezing of Gait Questionnaire (FOGQ).
The FOGQ evaluates the severity of freezing episodes and their impact on walking performance in patients with Parkinson disease.
The total score ranges from 0 to 24.
Higher scores indicate more severe freezing of gait and worse walking performance.
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Baseline, week 3, and week 6
|
Sekundære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
|---|---|---|
|
Falls Efficacy Scale
Tidsramme: Baseline, week 3, and week 6
|
Fall-related self-efficacy and fear of falling will be assessed using the Falls Efficacy Scale.
The scale evaluates the participant's confidence in performing daily activities without falling.
Scores range from 10 to 100, with lower scores indicating greater fear of falling and higher scores indicating lower fear of falling.
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Baseline, week 3, and week 6
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Timed Up and Go Test
Tidsramme: Baseline, week 3, and week 6
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r, walk a short distance, turn, walk back, and sit down.
The time required to complete the test will be recorded in seconds, with longer times indicating poorer functional mobility.
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Baseline, week 3, and week 6
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Functional Reach Test
Tidsramme: Baseline, week 3, and week 6
|
The Functional Reach Test will be used to assess dynamic balance and postural control.
The maximum distance the participant can reach forward while standing without losing balance will be recorded in centimeters.
Greater reach distance indicates better functional balance.
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Baseline, week 3, and week 6
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Sit-to-Stand Test
Tidsramme: Baseline, week 3, and week 6
|
The sit-to-stand task will be used to assess functional lower extremity performance and postural control during transition from sitting to standing.
The time required to complete the movement will be recorded in seconds using video-based analysis.
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Baseline, week 3, and week 6
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Gait Initiation Time
Tidsramme: Baseline, week 3, and week 6
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Gait initiation time will be assessed using video-based kinematic analysis.
The time from the auditory cue to the initiation of the first step will be recorded in seconds.
Longer times indicate impaired gait initiation.
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Baseline, week 3, and week 6
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Samarbeidspartnere og etterforskere
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Sponsor
Studierekorddatoer
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Studer hoveddatoer
Studiestart (Faktiske)
8. februar 2026
Primær fullføring (Faktiske)
1. juli 2026
Studiet fullført (Faktiske)
1. august 2026
Datoer for studieregistrering
Først innsendt
10. mai 2026
Først innsendt som oppfylte QC-kriteriene
10. mai 2026
Først lagt ut (Faktiske)
15. mai 2026
Oppdateringer av studieposter
Sist oppdatering lagt ut (Faktiske)
18. august 2026
Siste oppdatering sendt inn som oppfylte QC-kriteriene
14. august 2026
Sist bekreftet
1. august 2026
Mer informasjon
Begreper knyttet til denne studien
Ytterligere relevante MeSH-vilkår
Andre studie-ID-numre
- 2025/02-44
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