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Home-Based Exercise Programs for Fall Prevention in Parkinson Disease

15. maj 2026 opdateret af: Selim Mahmut GÜNAY, Uludag University

Effectiveness of Fall-Preventive Home Exercise Programs in Patients With Parkinson Disease: A Randomized Controlled Trial

Falls are common in patients with Parkinson disease and may lead to reduced mobility, fear of falling, loss of independence, and injury. Exercise-based rehabilitation programs may help improve balance, gait, and physical performance in this population.

This randomized controlled trial aims to compare the effectiveness of two home-based exercise programs in patients with Parkinson disease: the Otago Exercise Program and a structured home exercise program. Participants will be randomly assigned to one of two groups. Both groups will receive exercise education and will perform their assigned home exercise program for 6 weeks.

Participants will be evaluated at baseline, at week 3, and at the end of week 6. The study will assess fall-related outcomes, freezing of gait, functional mobility, gait parameters, postural control, and physical performance. The results may help determine which home-based exercise approach is more effective for reducing fall risk and improving functional outcomes in patients with Parkinson disease.

Studieoversigt

Status

Rekruttering

Betingelser

Intervention / Behandling

Undersøgelsestype

Interventionel

Tilmelding (Anslået)

30

Fase

  • Ikke anvendelig

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiekontakt

  • Navn: Selim GÜNAY, Asst Prof
  • Telefonnummer: +90 539 462 8521
  • E-mail: mgselim1@gmail.com

Studiesteder

  • Tyrkiet (Türkiye)
    • Antakya
      • Hatay, Antakya, Tyrkiet (Türkiye)
        • Rekruttering
        • Hatay Mustafa Kemal University
        • Kontakt:

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

  • Voksen
  • Ældre voksen

Tager imod sunde frivillige

Ingen

Beskrivelse

Inclusion Criteria:

  • Diagnosis of Parkinson disease confirmed by a neurologist
  • Hoehn and Yahr stage 3 or 4 Parkinson disease
  • Diagnosis of Parkinson disease for at least 5 years
  • Willingness to participate in the study and provide written informed consent
  • Ability to walk independently or with minimal assistance
  • Mini-Mental State Examination score >24

Exclusion Criteria:

  • Balance or gait impairment due to causes other than Parkinson disease, such as severe orthopedic problems or another neurological disease
  • Red flags suggestive of Parkinson-plus syndromes, such as symmetric onset, early falls, early-onset dementia, or gaze palsy
  • History of serious fall-related injury or surgery within the last 6 months
  • Any additional health condition that would prevent participation in the exercise program during the study period

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Behandling
  • Tildeling: Randomiseret
  • Interventionel model: Parallel tildeling
  • Maskning: Enkelt

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Eksperimentel: Otago Home Exercise Program
Participants in this arm will receive the Otago Home Exercise Program. The program includes home-based strengthening, static balance, and dynamic balance exercises designed to improve lower extremity muscle strength, balance, functional mobility, and fall-related outcomes. Participants will perform the exercises 3 times per week for 6 weeks, with each session lasting approximately 40 minutes. The exercise program will be reviewed and progressed at week 3 according to the participant's functional status.
Adfærdsmæssigt: Otago Home Exercise Program
nce exercises designed to improve lower extremity muscle strength, balance, functional mobility, and fall-related outcomes. Participants will perform the program 3 times per week for 6 weeks, with each session lasting approximately 40 minutes. The program will be reviewed and progressed at week 3.
Aktiv komparator: Structured Home Exercise Program
Participants in this arm will receive a structured home exercise program. The program includes spinal stabilization exercises and stretching and strengthening exercises targeting the ankle plantar flexor and dorsiflexor muscles, quadriceps, lumbar extensor muscles, pectoral muscles, and hamstring muscles. Participants will perform the exercises 3 times per week for 6 weeks, with each session lasting approximately 40 minutes. The exercise program will be reviewed and progressed at week 3 according to the participant's functional status.
Adfærdsmæssigt: Structured Home Exercise Program
The structured home exercise program is a home-based exercise intervention including spinal stabilization exercises and stretching and strengthening exercises targeting the ankle plantar flexor and dorsiflexor muscles, quadriceps, lumbar extensor muscles, pectoral muscles, and hamstring muscles. Participants will perform the program 3 times per week for 6 weeks, with each session lasting approximately 40 minutes. The program will be reviewed and progressed at week 3.

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Falls Efficacy Scale
Tidsramme: Baseline, week 3, and week 6
Fall-related self-efficacy and fear of falling will be assessed using the Falls Efficacy Scale. The scale evaluates the participant's confidence in performing daily activities without falling. Scores range from 10 to 100, with lower scores indicating greater fear of falling and higher scores indicating lower fear of falling.
Baseline, week 3, and week 6

Sekundære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Gait Speed
Tidsramme: Baseline, week 3, and week 6
Gait speed will be assessed using video-based kinematic analysis with Kinovea software. Walking speed will be calculated in meters per second from recorded walking trials. Higher gait speed indicates better walking performance.
Baseline, week 3, and week 6
Timed Up and Go Test
Tidsramme: Baseline, week 3, and week 6
r, walk a short distance, turn, walk back, and sit down. The time required to complete the test will be recorded in seconds, with longer times indicating poorer functional mobility.
Baseline, week 3, and week 6
Functional Reach Test
Tidsramme: Baseline, week 3, and week 6
The Functional Reach Test will be used to assess dynamic balance and postural control. The maximum distance the participant can reach forward while standing without losing balance will be recorded in centimeters. Greater reach distance indicates better functional balance.
Baseline, week 3, and week 6
Sit-to-Stand Test
Tidsramme: Baseline, week 3, and week 6
The sit-to-stand task will be used to assess functional lower extremity performance and postural control during transition from sitting to standing. The time required to complete the movement will be recorded in seconds using video-based analysis.
Baseline, week 3, and week 6
Gait Initiation Time
Tidsramme: Baseline, week 3, and week 6
Gait initiation time will be assessed using video-based kinematic analysis. The time from the auditory cue to the initiation of the first step will be recorded in seconds. Longer times indicate impaired gait initiation.
Baseline, week 3, and week 6
Freezing of Gait Questionnaire (FOGQ)
Tidsramme: Baseline, week 3, and week 6
Freezing of gait will be assessed using the Freezing of Gait Questionnaire (FOGQ). The FOGQ evaluates the severity of freezing episodes and their impact on walking performance in patients with Parkinson disease. The total score ranges from 0 to 24. Higher scores indicate more severe freezing of gait and worse walking performance.
Baseline, week 3, and week 6

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Uludag University

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

8. februar 2026

Primær færdiggørelse (Anslået)

1. juli 2026

Studieafslutning (Anslået)

1. august 2026

Datoer for studieregistrering

Først indsendt

10. maj 2026

Først indsendt, der opfyldte QC-kriterier

10. maj 2026

Først opslået (Faktiske)

15. maj 2026

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

19. maj 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

15. maj 2026

Sidst verificeret

1. maj 2026

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

  • 2025/02-44

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