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Impact of Mirror Therapy Combined With Conventional Training on Gait and Lower Limb Motor Function Among Post-Stroke Patients

2026年8月28日 更新者:Ibadat International University, Islamabad
This randomized controlled trial aims to evaluate the effects of mirror therapy combined with conventional training on gait and lower limb motor function among post-stroke patients. Stroke remains a worldwide health crisis, persistently ranking as a leading cause of long-term severe disability. The study will evaluate the gait and lower limb motor function.

調査の概要

研究の種類

介入

入学 (推定)

52

段階

  • 適用できない

連絡先と場所

このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。

研究連絡先

研究連絡先のバックアップ

研究場所

    • Balochistan
      • Quetta、Balochistan、パキスタン
        • 募集
        • Department of Physical Therapy at suleman medical complex hospital, Quetta.
        • コンタクト:
          • Dr Nazish Rafique
          • 電話番号:+923138092081
          • メール:ammar@gmail.com

参加基準

研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。

適格基準

就学可能な年齢

  • 大人
  • 高齢者

健康ボランティアの受け入れ

いいえ

説明

Inclusion Criteria:

  • Diagnosed with the first-ever unilateral stroke.
  • Duration of stroke between 3 months and 6 months (subacute to chronic stage).
  • Both male and female patients aged 40 to 70 years.
  • Ability to walk at least 10 meters independently.
  • Mini Mental State Examination (MMSE) score >24.
  • Brunnstrom stage of recovery for the lower limb is > 3, indicating some voluntary movement out of synergy.

Exclusion Criteria:

  • Severe cognitive impairment, perceptual deficits, or inability to follow simple verbal commands (e.g., severe aphasia or low MMSE score).
  • Presence of other neurological disorders affecting motor performance such as Parkinson's disease, multiple sclerosis, traumatic brain injury, or cerebellar disorders.
  • Severe musculoskeletal disorders of the lower limb, including fracture, contracture, severe osteoarthritis, or pain limiting participation in exercise.
  • Uncontrolled medical conditions such as unstable hypertension, uncontrolled diabetes mellitus, a recent cardiac event, or other conditions making exercise unsafe.
  • Severe visual impairment, vestibular dysfunction, or hearing loss that may interfere with treatment instructions or mirror-based feedback.
  • Severe unilateral neglect (hemispatial neglect) or apraxia interfering with task performance.
  • Current participation in another physiotherapy, rehabilitation, or interventional research study during the data collection period.

研究計画

このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。

研究はどのように設計されていますか?

デザインの詳細

  • 主な目的:処理
  • 割り当て:ランダム化
  • 介入モデル:並列代入
  • マスキング:独身

武器と介入

参加者グループ / アーム
介入・治療
実験的:Group A
Participants in this group will receive mirror therapy-based functional training with conventional lower limb training. This training program will focus on gait and lower limb motor function.

(Basic) - Sitting position:

  • Ankle dorsiflexion/plantarflexion (simulating pressing a gas pedal)
  • Knee extension/flexion (simulating kicking a ball)
  • Hip flexion/extension (simulating marching)
  • Ankle circling in both directions (Intermediate)-Sitting to standing transition:
  • Performing "stepping" movements while seated
  • Simulated sit-to-stand movements focusing on weight transfer observed in the reflection
  • Sliding the foot forward and backward along the floor (simulating the swing phase of gait)
  • Heel slides (Advanced) - Standing position:
  • Heel raises and toe raises in standing
  • Weight shifting between limbs observing symmetry in the mirror
  • Mini squats and half squats with mirror feedback
  • Stepping forward, backward, and laterally
  • Tracing shapes or following a moving target with the foot
  • Practicing coordinated ankle movements essential for navigating uneven terrain.

Passive and active-assisted range of motion exercises for hip, knee, and ankle joints of the affected limb

  • Bridging exercises
  • Ankle dorsiflexion/plantarflexion against manual resistance or TheraBand
  • Seated knee extension
  • Mini squats
  • Heel raises
  • Straight leg raises
  • Weight shifting in standing (side-to-side and front-toback)
  • Sit-to-stand transfers
  • Tandem standing
  • Single-leg stance (with support as needed)
  • Standing on foam surface (if available)
  • Practice walking on level surfaces with emphasis on weight-bearing on affected limb
  • Focus on heel strike and push-off phases
  • Verbal cues for step length and symmetry
  • Gait speed variations (slow to moderate pace)
  • Gentle stretching of hamstrings, quadriceps, gastrocnemius, and soleus muscles
アクティブコンパレータ:Group B
Participants in this group will receive conventional lower limb training. This training program will focus on gait and lower limb motor function.

Passive and active-assisted range of motion exercises for hip, knee, and ankle joints of the affected limb

  • Bridging exercises
  • Ankle dorsiflexion/plantarflexion against manual resistance or TheraBand
  • Seated knee extension
  • Mini squats
  • Heel raises
  • Straight leg raises
  • Weight shifting in standing (side-to-side and front-toback)
  • Sit-to-stand transfers
  • Tandem standing
  • Single-leg stance (with support as needed)
  • Standing on foam surface (if available)
  • Practice walking on level surfaces with emphasis on weight-bearing on affected limb
  • Focus on heel strike and push-off phases
  • Verbal cues for step length and symmetry
  • Gait speed variations (slow to moderate pace)
  • Gentle stretching of hamstrings, quadriceps, gastrocnemius, and soleus muscles

この研究は何を測定していますか?

主要な結果の測定

結果測定
メジャーの説明
時間枠
10-Meter Walk Test (10MWT)
時間枠:Baseline, Weeks 3 and 6.
This test measures gait speed (m/s) over a short distance and is a highly sensitive measure of functional walking ability. It has excellent test-retest reliability (ICC = 0.95 to 0.99) in individuals with chronic stroke and is considered a valid core outcome measure for gait recovery.
Baseline, Weeks 3 and 6.
Timed Up and Go Test (TUG)
時間枠:Baseline, Weeks 3 and 6.
This test assesses functional mobility and dynamic balance by measuring the time (in seconds) it takes an individual to stand up from a chair, walk 3 meters, turn, walk back, and sit down. It demonstrates excellent reliability (ICC = 0.95) in the stroke population and is highly responsive to changes in mobility.
Baseline, Weeks 3 and 6.
Fugl-Meyer Assessment for Lower Extremity (FMA-LE)
時間枠:Baseline, Weeks 3 and 6.
This is a stroke-specific performance-based impairment index used to quantitatively measure motor function, sensation, and coordination in the lower limb. It is widely regarded as the gold standard for assessing motor recovery after stroke, with high inter-rater reliability (ICC = 0.97).
Baseline, Weeks 3 and 6.
Wisconsin Gait Scale (WGS)
時間枠:Baseline, Weeks 3 and 6.
This is a valid and reliable observational gait analysis tool specifically designed for the qualitative assessment of hemiplegic gait. It assesses 14 observable parameters across different phases of gait (e.g., stance, swing) and has high inter-rater (r = 0.91) and test-retest (r = 0.92) reliability in stroke patients (Rodriquez et al., 1996). The WGS was selected to capture the nuanced spatiotemporal improvements in gait pattern (e.g., step length, symmetry) that are clinically meaningful but may not be fully reflected in speed or timed tests alone.
Baseline, Weeks 3 and 6.

協力者と研究者

ここでは、この調査に関係する人々や組織を見つけることができます。

出版物と役立つリンク

研究に関する情報を入力する責任者は、自発的にこれらの出版物を提供します。これらは、研究に関連するあらゆるものに関するものである可能性があります。

一般刊行物

  • GBD 2021 Stroke Collaborators. (2023). Global, regional, and national burden of stroke and its risk factors, 1990-2021: A systematic analysis for the Global Burden of Disease Study 2021. The Lancet Neurology, 22(10), 915-939. 2. Khan, M., Ahmed, S., & Anwar, S. (2022). Burden of stroke in Pakistan: A growing concern. Journal of Pakistan Medical Association, 72(2), 242-246. 3. Li, S., Francisco, G. E., & Zhou, P. (2018). Post-stroke hemiplegic gait: New perspective and insights. Physical Medicine and Rehabilitation Clinics of North America, 29(4), 719-735. 4. Hatem, S. M., Saussez, G., Della Faille, M., Prist, V., Zhang, X., Dispa, D., et al. (2016). Rehabilitation of motor function after stroke: A multiple systematic review focused on techniques to stimulate upper extremity recovery. Frontiers in Human Neuroscience, 10, 442. 5. Garrison, K. A., Winstein, C. J., & Aziz-Zadeh, L. (2010). The mirror neuron system: A neural substrate for methods in stroke rehabilitation. Neurorehabilitation and Neural Repair, 24(5), 404-412. 6. Thieme, H., Morkisch, N., Mehrholz, J., Pohl, M., Behrens, J., & Dohle, C. (2018). Mirror therapy for improving motor function after stroke. Cochrane Database of Systematic Reviews, 7, CD008449. 7. Broderick, P., Horgan, F., Blake, C., & O'Keeffe, M. (2022). Mirror therapy for improving lower limb motor function and mobility after stroke: A systematic review and meta-analysis. Clinical Rehabilitation, 36(4), 437-453. 8. Veerbeek, J. M., van Wegen, E., van Peppen, R., van der Wees, P. J., Hendriks, E., Rietberg, M., et al. (2014). What is the evidence for physical therapy poststroke? A systematic review and meta-analysis. PLoS ONE, 9(2), e87987. 9. Hornby, T. G., Reisman, D. S., Ward, I. G., Scheets, P. L., Miller, A., Haddad, D., et al. (2020). Clinical practice guideline to improve locomotor function following chronic stroke, incomplete spinal cord injury, and brain injury. Journal of Neurologic Physical Therapy, 44(1), 49-100.

研究記録日

これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。

主要日程の研究

研究開始 (実際)

2026年4月15日

一次修了 (推定)

2026年9月20日

研究の完了 (推定)

2026年9月25日

試験登録日

最初に提出

2026年7月6日

QC基準を満たした最初の提出物

2026年8月28日

最初の投稿 (実際)

2026年9月1日

学習記録の更新

投稿された最後の更新 (実際)

2026年9月1日

QC基準を満たした最後の更新が送信されました

2026年8月28日

最終確認日

2026年5月1日

詳しくは

本研究に関する用語

その他の研究ID番号

  • IIUI/RERC/ADT/2026/05/260

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いいえ

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