Impact of Mirror Therapy Combined With Conventional Training on Gait and Lower Limb Motor Function Among Post-Stroke Patients
2026年8月28日 更新者:Ibadat International University, Islamabad
This randomized controlled trial aims to evaluate the effects of mirror therapy combined with conventional training on gait and lower limb motor function among post-stroke patients.
Stroke remains a worldwide health crisis, persistently ranking as a leading cause of long-term severe disability.
The study will evaluate the gait and lower limb motor function.
研究概览
研究类型
介入性
注册 (估计的)
52
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。
学习联系方式
- 姓名:Muhammad Ammar Muhammad Ammar, DPT, MS-PT NPT
- 电话号码:+923138092081
- 邮箱:ammarkhanazxc36@gmail.com
研究联系人备份
- 姓名:Dr Nazish Rafique, DPT, MS-PT NMPT
- 电话号码:+923002132436
- 邮箱:nazish.rafique@uipt.iiui.edu.pk
学习地点
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Balochistan
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Quetta、Balochistan、巴基斯坦
- 招聘中
- Department of Physical Therapy at suleman medical complex hospital, Quetta.
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接触:
- Dr Nazish Rafique
- 电话号码:+923138092081
- 邮箱:ammar@gmail.com
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参与标准
研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
不
描述
Inclusion Criteria:
- Diagnosed with the first-ever unilateral stroke.
- Duration of stroke between 3 months and 6 months (subacute to chronic stage).
- Both male and female patients aged 40 to 70 years.
- Ability to walk at least 10 meters independently.
- Mini Mental State Examination (MMSE) score >24.
- Brunnstrom stage of recovery for the lower limb is > 3, indicating some voluntary movement out of synergy.
Exclusion Criteria:
- Severe cognitive impairment, perceptual deficits, or inability to follow simple verbal commands (e.g., severe aphasia or low MMSE score).
- Presence of other neurological disorders affecting motor performance such as Parkinson's disease, multiple sclerosis, traumatic brain injury, or cerebellar disorders.
- Severe musculoskeletal disorders of the lower limb, including fracture, contracture, severe osteoarthritis, or pain limiting participation in exercise.
- Uncontrolled medical conditions such as unstable hypertension, uncontrolled diabetes mellitus, a recent cardiac event, or other conditions making exercise unsafe.
- Severe visual impairment, vestibular dysfunction, or hearing loss that may interfere with treatment instructions or mirror-based feedback.
- Severe unilateral neglect (hemispatial neglect) or apraxia interfering with task performance.
- Current participation in another physiotherapy, rehabilitation, or interventional research study during the data collection period.
学习计划
本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。
研究是如何设计的?
设计细节
- 主要用途:治疗
- 分配:随机化
- 介入模型:并行分配
- 屏蔽:单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的:Group A
Participants in this group will receive mirror therapy-based functional training with conventional lower limb training.
This training program will focus on gait and lower limb motor function.
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(Basic) - Sitting position:
Passive and active-assisted range of motion exercises for hip, knee, and ankle joints of the affected limb
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有源比较器:Group B
Participants in this group will receive conventional lower limb training.
This training program will focus on gait and lower limb motor function.
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Passive and active-assisted range of motion exercises for hip, knee, and ankle joints of the affected limb
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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10-Meter Walk Test (10MWT)
大体时间:Baseline, Weeks 3 and 6.
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This test measures gait speed (m/s) over a short distance and is a highly sensitive measure of functional walking ability.
It has excellent test-retest reliability (ICC = 0.95 to 0.99) in individuals with chronic stroke and is considered a valid core outcome measure for gait recovery.
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Baseline, Weeks 3 and 6.
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Timed Up and Go Test (TUG)
大体时间:Baseline, Weeks 3 and 6.
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This test assesses functional mobility and dynamic balance by measuring the time (in seconds) it takes an individual to stand up from a chair, walk 3 meters, turn, walk back, and sit down.
It demonstrates excellent reliability (ICC = 0.95) in the stroke population and is highly responsive to changes in mobility.
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Baseline, Weeks 3 and 6.
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Fugl-Meyer Assessment for Lower Extremity (FMA-LE)
大体时间:Baseline, Weeks 3 and 6.
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This is a stroke-specific performance-based impairment index used to quantitatively measure motor function, sensation, and coordination in the lower limb.
It is widely regarded as the gold standard for assessing motor recovery after stroke, with high inter-rater reliability (ICC = 0.97).
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Baseline, Weeks 3 and 6.
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Wisconsin Gait Scale (WGS)
大体时间:Baseline, Weeks 3 and 6.
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This is a valid and reliable observational gait analysis tool specifically designed for the qualitative assessment of hemiplegic gait.
It assesses 14 observable parameters across different phases of gait (e.g., stance, swing) and has high inter-rater (r = 0.91) and test-retest (r = 0.92) reliability in stroke patients (Rodriquez et al., 1996).
The WGS was selected to capture the nuanced spatiotemporal improvements in gait pattern (e.g., step length, symmetry) that are clinically meaningful but may not be fully reflected in speed or timed tests alone.
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Baseline, Weeks 3 and 6.
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
一般刊物
- GBD 2021 Stroke Collaborators. (2023). Global, regional, and national burden of stroke and its risk factors, 1990-2021: A systematic analysis for the Global Burden of Disease Study 2021. The Lancet Neurology, 22(10), 915-939. 2. Khan, M., Ahmed, S., & Anwar, S. (2022). Burden of stroke in Pakistan: A growing concern. Journal of Pakistan Medical Association, 72(2), 242-246. 3. Li, S., Francisco, G. E., & Zhou, P. (2018). Post-stroke hemiplegic gait: New perspective and insights. Physical Medicine and Rehabilitation Clinics of North America, 29(4), 719-735. 4. Hatem, S. M., Saussez, G., Della Faille, M., Prist, V., Zhang, X., Dispa, D., et al. (2016). Rehabilitation of motor function after stroke: A multiple systematic review focused on techniques to stimulate upper extremity recovery. Frontiers in Human Neuroscience, 10, 442. 5. Garrison, K. A., Winstein, C. J., & Aziz-Zadeh, L. (2010). The mirror neuron system: A neural substrate for methods in stroke rehabilitation. Neurorehabilitation and Neural Repair, 24(5), 404-412. 6. Thieme, H., Morkisch, N., Mehrholz, J., Pohl, M., Behrens, J., & Dohle, C. (2018). Mirror therapy for improving motor function after stroke. Cochrane Database of Systematic Reviews, 7, CD008449. 7. Broderick, P., Horgan, F., Blake, C., & O'Keeffe, M. (2022). Mirror therapy for improving lower limb motor function and mobility after stroke: A systematic review and meta-analysis. Clinical Rehabilitation, 36(4), 437-453. 8. Veerbeek, J. M., van Wegen, E., van Peppen, R., van der Wees, P. J., Hendriks, E., Rietberg, M., et al. (2014). What is the evidence for physical therapy poststroke? A systematic review and meta-analysis. PLoS ONE, 9(2), e87987. 9. Hornby, T. G., Reisman, D. S., Ward, I. G., Scheets, P. L., Miller, A., Haddad, D., et al. (2020). Clinical practice guideline to improve locomotor function following chronic stroke, incomplete spinal cord injury, and brain injury. Journal of Neurologic Physical Therapy, 44(1), 49-100.
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2026年4月15日
初级完成 (估计的)
2026年9月20日
研究完成 (估计的)
2026年9月25日
研究注册日期
首次提交
2026年7月6日
首先提交符合 QC 标准的
2026年8月28日
首次发布 (实际的)
2026年9月1日
研究记录更新
最后更新发布 (实际的)
2026年9月1日
上次提交的符合 QC 标准的更新
2026年8月28日
最后验证
2026年5月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.