Design and Implementation of the Puerto Rico Observational Study of Psychosocial, Environmental, and Chronic Disease Trends (PROSPECT)

Josiemer Mattei, Katherine L Tucker, Luis M Falcón, Carlos F Ríos-Bedoya, Robert M Kaplan, H June O'Neill, Martha Tamez, Sigrid Mendoza, Claudia B Díaz-Álvarez, Jonathan E Orozco, Edna Acosta Pérez, José F Rodríguez-Orengo, Josiemer Mattei, Katherine L Tucker, Luis M Falcón, Carlos F Ríos-Bedoya, Robert M Kaplan, H June O'Neill, Martha Tamez, Sigrid Mendoza, Claudia B Díaz-Álvarez, Jonathan E Orozco, Edna Acosta Pérez, José F Rodríguez-Orengo

Abstract

The Puerto Rico Observational Study of Psychosocial, Environmental, and Chronic Disease Trends (PROSPECT) is a prospective cohort study in Puerto Rico (PR) aiming to identify trends and longitudinal associations in risk factors for cardiovascular disease (CVD). In 2019, PROSPECT investigators started recruiting a sample of 2,000 adults aged 30-75 years in PR using multistage probabilistic sampling of households and community approaches. Culturally sensitive trained research assistants assess participants, at baseline and at 2-year follow-up, in private rooms at a network of partner clinics. The study collects comprehensive data on demographic factors, socioeconomic and environmental factors, medical history, health conditions, lifestyle behaviors, psychosocial status, and biomarkers of CVD and stress. PROSPECT will estimate the prevalence and incidence of psychosocial, lifestyle, and biological CVD risk factors, describe variations in risk factors by urbanicity (urban areas vs. rural areas) and exposure (before and after) to natural disasters, and determine predictors of longitudinal changes in CVD risk factors. The study has 4 coordinated operational strategies: 1) research productivity (including synergy with existing epidemiologic cohorts of Hispanics/Latinos for comparison); 2) research infrastructure (biorepository, ancillary studies, and clinical research network); 3) capacity-building, education, and training; and 4) community outreach, dissemination, and policy. PROSPECT will inform public health priorities to help reduce CVD in PR.

Keywords: chronic diseases; cohort studies; health disparities; longitudinal studies; minority populations.

© The Author(s) 2020. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Figures

Figure 1
Figure 1
Locations (stars) of partner clinics and hospitals where clinical procedures will be carried out and participants will be interviewed in the Puerto Rico Observational Study of Psychosocial, Environmental, and Chronic Disease Trends.
Figure 2
Figure 2
Coordinated operational strategies led by the Puerto Rico Observational Study of Psychosocial, Environmental, and Chronic Disease Trends (PROSPECT).
Figure 3
Figure 3
Lessons learned from the Puerto Rico Observational Study of Psychosocial, Environmental, and Chronic Disease Trends.

Source: PubMed

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