Diagnosis and Management of Diabetic Foot Infections

Excerpt

This compendium is a follow-up to the 2018 American Diabetes Association compendium Diagnosis and Management of Diabetic Foot Complications. Whereas the first compendium offered a broad general overview of diabetic foot conditions, this second volume presents a detailed discussion of the prevention and treatment of diabetic foot infections (DFIs), a major contributor to high amputation rates among people with diabetes. The treatise begins from the viewpoint of basic science, describing the impact of infection on the healing process of experimental wounds. There follow overviews of biofilm development in chronic diabetic foot ulcers (DFUs), the microbiology of DFIs, and the crucial role of debridement in ensuring positive outcomes of DFI treatment. Next, the authors provide a practical guide to the diagnosis and clinical management of DFIs. Current controversies regarding the treatment of osteomyelitis are addressed, including the relative value of antibiotics versus surgery and the use of intravenous versus oral antibiotics. The compendium closes with a look at new topical treatments and the role of emerging technologies in infection control.

Conflict of interest statement

DUALITIES OF INTEREST

A.J.M.B., D.G.A., M.J.H., J.M.E., C.E.A., B.A.L., J.A.-S., G.S., and R.S.K. have no relevant dualities of interest to disclose. M.M. has received research grants and consultant fees for educational activities from Smith & Nephew in the area of wound biofilm. The work of H.K.L. was funded by the National Institute for Health Research—Health Training Assessment.

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