Intratracheal recombinant human deoxyribonuclease in acute life-threatening asthma refractory to conventional treatment
A Patel, E Harrison, A Durward, I A Murdoch, A Patel, E Harrison, A Durward, I A Murdoch
Abstract
Recombinant human deoxyribonuclease (rhDNase) is a mucolytic agent used to relieve peripheral airway obstruction in patients with cystic fibrosis. We report dramatic sustained improvement following the intratracheal administration of rhDNase to a 3-yr-old boy with acute life-threatening asthma in whom 48 h of aggressive therapy had failed.
Source: PubMed