Randomised controlled trial of infantile colic treated with chiropractic spinal manipulation

E Olafsdottir, S Forshei, G Fluge, T Markestad, E Olafsdottir, S Forshei, G Fluge, T Markestad

Abstract

Aims: To investigate the efficacy of chiropractic spinal manipulation in the management of infantile colic.

Methods: One hundred infants with typical colicky pain were recruited to a randomised, blinded, placebo controlled clinical trial.

Results: Nine infants were excluded because inclusion criteria were not met, and five dropped out, leaving 86 who completed the study. There was no significant effect of chiropractic spinal manipulation. Thirty two of 46 infants in the treatment group (69.9%), and 24 of 40 in the control group (60.0%), showed some degree of improvement.

Conclusion: Chiropractic spinal manipulation is no more effective than placebo in the treatment of infantile colic. This study emphasises the need for placebo controlled and blinded studies when investigating alternative methods to treat unpredictable conditions such as infantile colic.

References

    1. J Child Psychol Psychiatry. 1991 Sep;32(6):951-68
    1. Pediatrics. 1954 Nov;14(5):421-35
    1. J Manipulative Physiol Ther. 1999 Oct;22(8):517-22
    1. Acta Paediatr Suppl. 1999 Aug;88(430):58-60
    1. J Pediatr Gastroenterol Nutr. 2000;30 Suppl:S67-76
    1. Br Med J (Clin Res Ed). 1984 Mar 24;288(6421):901
    1. Pediatrics. 1984 Dec;74(6):998-1003
    1. Eur J Pediatr. 1984 Dec;143(2):108-11
    1. Arch Dis Child. 1985 Oct;60(10):981-5
    1. Pediatrics. 1986 May;77(5):641-8
    1. Ugeskr Laeger. 1988 Jul 25;150(30):1841-4
    1. Pediatrics. 1989 Feb;83(2):262-6
    1. J Manipulative Physiol Ther. 1989 Aug;12(4):281-8
    1. J Pediatr. 1989 Oct;115(4):521-6
    1. Pediatr Clin North Am. 1991 Dec;38(6):1407-23
    1. Pediatrics. 1962 Apr;29:579-88
    1. Curr Med Res Opin. 1977;5(3):258-61
    1. Pediatrics. 1992 Jul;90(1 Pt 1):14-21
    1. Pediatrics. 1994 Jul;94(1):29-34
    1. BMJ. 1995 Jun 10;310(6993):1498-500
    1. J Allergy Clin Immunol. 1995 Dec;96(6 Pt 1):886-92
    1. Acta Paediatr. 1996 Apr;85(4):454-8
    1. Acta Paediatr. 1996 Apr;85(4):463-6
    1. Arch Dis Child. 1996 Nov;75(5):375-84
    1. Arch Dis Child. 1997 Jan;76(1):1-3
    1. N Engl J Med. 1998 Oct 8;339(15):1013-20
    1. J Pediatr Health Care. 1998 Sep-Oct;12(5):256-62
    1. J Manipulative Physiol Ther. 1999 Jun;22(5):292-8
    1. J Manipulative Physiol Ther. 1999 Jul-Aug;22(6):376-81
    1. Arch Dis Child. 1954 Jun;29(145):165-74

Source: PubMed

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