Clinical Uses of Membrane Lipid Replacement Supplements in Restoring Membrane Function and Reducing Fatigue in Chronic Diseases and Cancer

Garth L Nicolson, Steven Rosenblatt, Gonzalo Ferreira de Mattos, Robert Settineri, Paul C Breeding, Rita R Ellithorpe, Michael E Ash, Garth L Nicolson, Steven Rosenblatt, Gonzalo Ferreira de Mattos, Robert Settineri, Paul C Breeding, Rita R Ellithorpe, Michael E Ash

Abstract

Membrane Lipid Replacement is the use of functional oral supplements containing cell membrane glycerolphospholipids and antioxidants to safely replace damaged membrane lipids that accumulate during aging and in various chronic and acute diseases. Most if not all clinical conditions and aging are characterized by membrane phospholipid oxidative damage, resulting in loss of membrane and cellular function. Clinical trials have shown the benefits of Membrane Lipid Replacement supplements in replenishing damaged membrane lipids and restoring mitochondrial function, resulting in reductions in fatigue in aged subjects and patients with a variety of clinical diagnoses. Recent observations have indicated that Membrane Lipid Replacement can be a useful natural supplement strategy in a variety of conditions: chronic fatigue, such as found in many diseases and disorders; fatiguing illnesses (fibromyalgia and chronic fatigue syndrome); chronic infections (Lyme disease and mycoplasmal infections); cardiovascular diseases; obesity, metabolic syndrome and diabetes; neurodegenerative diseases (Alzheimer's disease); neurobehavioral diseases (autism spectrum disorders); fertility diseases; chemical contamination (Gulf War illnesses); and cancers (breast, colorectal and other cancers). Membrane Lipid Replacement provides general membrane nutritional support during aging and illness to improve membrane function and overall health without risk of adverse effects.

Keywords: Membrane phospholipids; aging; cancer; cardiovascular diseases; chemical contamination; chronic diseases; chronic infections; clinical trials; diabetes; fatigue; fertility; lipid oxidation; metabolic diseases; metabolic syndrome; mitochondrial function; neurobehavioral diseases; neurodegenerative diseases; obesity.

Conflict of interest statement

Conflict of interests: Garth Nicolson and Robert Settineri are part-time consultants to Nutritional Therapeutics, Inc. of Hauppuage, NY; Researched Nutritionals of Los Olivos, CA; Allergy Research Group of Alameda, CA; and Naturally Plus USA of LasVegas, NV. Settineri is also a consultant to Advanced Biocatalytics of Irvine, CA. Steven Rosenblatt and Gonzalo Ferreira de Mattos have no conflicts to report. Rita Ellithorpe is a part-time consultant to Nutritional Therapeutics, Inc. of Hauppuage, NY; and Researched Nutritionals of Los Olivos, CA; Michael Ash is a part-time consultant to Allergy Research Group of Alameda, CA.

Copyright © 2016, Applied Systems.

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