Prevalence and Risk Factors of Sarcopenia among Older Adults Aged ≥65 Years Admitted to Daycare Centers of Taiwan: Using AWGS 2019 Guidelines

Cheng-Fen Chang, Yu-Lyu Yeh, Huang-Yu Chang, Sheng-Hua Tsai, Jiun-Yi Wang, Cheng-Fen Chang, Yu-Lyu Yeh, Huang-Yu Chang, Sheng-Hua Tsai, Jiun-Yi Wang

Abstract

Sarcopenia is a geriatric syndrome which is likely to cause disability, body unbalance, and mortality and thus can lead to heavy healthcare expenditure and caregiver burden. Although some studies have addressed the prevalence of sarcopenia for older adults, there are limited studies conducted in daycare centers. The present study aimed to (i) estimate the prevalence of sarcopenia and (ii) explore associated factors of sarcopenia and standing balance among older adults admitted to daycare centers in Taiwan. The cross-sectional study collected data on demographics, health status, handgrip strength, gait speed (GS), skeletal muscle mass, Taiwan-Mini Nutritional Assessment Short-Form (TW-MNA-SF), and Short Physical Performance Battery from daycare centers in northern Taiwan. The definition of sarcopenia followed the Asian Working Group for Sarcopenia 2019 guidelines. Among 173 participants ≥65 year-old, 50.9% had confirmed sarcopenia, 47.4% possible sarcopenia, and 1.7% normal. Results showed that calf circumference, TW-MNA-SF, dementia, and body mass index (BMI) were associated with sarcopenia. Moreover, BMI, GS, and sarcopenia were associated factors of standing balance. The study estimated a high prevalence of sarcopenia in daycare centers and identified some significant factors of sarcopenia and standing balance. Early nutritional and physiotherapy interventions could benefit older adults to prevent sarcopenia or unbalance.

Keywords: daycare center; older adults; prevalence; sarcopenia; standing balance.

Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Flow chart of the selection of study participants.

References

    1. Sanchez-Rodriguez D., Hope S., Piotrowicz K., Benoit F., Czesak J., Dallmeier D., Decker G., De Spiegeleer A., Højmann A.H., Hrnciarikova D., et al. Sarcopenia in acute care patients: Protocol for the European collaboration of geriatric surveys: Sarcopenia 9+ EAMA Project. J. Am. Med. Dir. Assoc. 2019;20:e1–e3. doi: 10.1016/j.jamda.2019.04.030.
    1. Vrbova P., Smaha J., Stepan J., Tobias D., Kuzma M., Payer J., Koller T. Prevalence of sarcopenia among hospitalized internal medicine patients: A cross-sectional single-center pilot study according to EWGSOP2 criteria. Bratisl. Lek. Listy. 2019;120:717–722. doi: 10.4149/BLL_2019_128.
    1. Wu C.H., Chen K.T., Hou M.T., Chang Y.F., Chang C.S., Liu P.Y., Wu S.J., Chiu C.J., Jou I.M., Chen C.Y. Prevalence and associated factors of sarcopenia and severe sarcopenia in older Taiwanese living in rural community: The Tianliao old people study 04. Geriatr. Gerontol. Int. 2014;14:69–75. doi: 10.1111/ggi.12233.
    1. Moon S.-S. Low skeletal muscle mass is associated with insulin resistance, diabetes, and metabolic syndrome in the Korean population: The Korea National Health and Nutrition Examination Survey (KNHANES) 2009–2010. Endocr. J. 2014;61:61–70. doi: 10.1507/endocrj.EJ13-0244.
    1. Goodpaster B.H., Park S.W., Harris T.B., Kritchevsky S.B., Nevitt M., Schwartz A.V., Simonsick E.M., Tylavsky F.A., Visser M., Newman A.B. The loss of skeletal muscle strength, mass, and quality in older adults: The health, aging and body composition study. J. Gerontol. A Biol. Sci. Med. Sci. 2006;61:1059–1064. doi: 10.1093/gerona/61.10.1059.
    1. Patel H.P., Syddall H.E., Jameson K., Robinson S., Denison H., Roberts H.C., Edwards M., Dennison E., Cooper C., Aihie Sayer A. Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: Findings from the Hertfordshire Cohort Study (HCS) Age Ageing. 2013;42:378–384. doi: 10.1093/ageing/afs197.
    1. De Magalhães A.M., Gomes B.B., Cerceau D.M., de Oliveira G.V., Parreiras de Menezes K.K. Assessment of balance, gait, lower limb strength and functionality in sarcopenic and non-sarcopenic elderlies. MTP Rehabil. J. 2020;18:1–7. doi: 10.17784/mtprehabjournal.2020.18.807.
    1. Waters D.L., Baumgartner R.N., Garry P.J., Vellas B. Advantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: An update. Clin. Interv. Aging. 2010;5:259–270. doi: 10.2147/CIA.S6920.
    1. Bertschi D., Kiss C.M., Beerli N., Kressig R.W. Sarcopenia in hospitalized geriatric patients: Insights into prevalence and associated parameters using new EWGSOP2 guidelines. Eur. J. Clin. Nutr. 2021;75:653–660. doi: 10.1038/s41430-020-00780-7.
    1. Baumgartner R.N., Koehler K.M., Gallagher D., Romero L., Heymsfield S.B., Ross R.R., Garry P.J., Lindeman R.D. Epidemiology of sarcopenia among the elderly in New Mexico. Am. J. Epidemiol. 1998;147:755–763. doi: 10.1093/oxfordjournals.aje.a009520.
    1. Senior H.E., Henwood T.R., Beller E.M., Mitchell G.K., Keogh J.W. Prevalence and risk factors of sarcopenia among adults living in nursing homes. Maturitas. 2015;82:418–423. doi: 10.1016/j.maturitas.2015.08.006.
    1. Lovett M., Negm A., Ioannidis G., Petrucelli D., Winemaker M., Adachi J.D., Papaioannou A. Identifying Patients with Osteoarthritis at Risk of Sarcopenia using the SARC-F. J. Geriatr. Cardiol. 2021;24:1–7. doi: 10.5770/cgj.24.479.
    1. Meng N.H., Li C.I., Liu C.S., Lin C.H., Lin W.Y., Chang C.K., Li T.C., Lin C.C. Comparison of height- and weight-adjusted sarcopenia in a Taiwanese metropolitan older population. Geriatr. Gerontol. Int. 2015;15:45–53. doi: 10.1111/ggi.12227.
    1. Han D.-S., Chang K.-V., Li C.-M., Lin Y.-H., Kao T.-W., Tsai K.-S., Wang T.-G., Yang W.-S. Skeletal muscle mass adjusted by height correlated better with muscular functions than that adjusted by body weight in defining sarcopenia. Sci. Rep. 2016;6:1–8. doi: 10.1038/srep19457.
    1. Chen Y.-P., Wong P.-K., Tsai M., Jr., Chang W.-C., Hsieh T.-S., Leu T.-H., Jeff Lin C.-F., Lee C.-H., Kuo Y.-J., Lin C.-Y. The high prevalence of sarcopenia and its associated outcomes following hip surgery in Taiwanese geriatric patients with a hip fracture. J. Formos. Med. Assoc. 2020;119:1807–1816. doi: 10.1016/j.jfma.2020.02.004.
    1. Chen L.K., Liu L.K., Woo J., Assantachai P., Auyeung T.W., Bahyah K.S., Chou M.Y., Chen L.Y., Hsu P.S., Krairit O., et al. Sarcopenia in Asia: Consensus report of the Asian Working Group for Sarcopenia. J. Am. Med. Dir. Assoc. 2014;15:95–101. doi: 10.1016/j.jamda.2013.11.025.
    1. Chen L.K., Woo J., Assantachai P., Auyeung T.W., Chou M.Y., Iijima K., Jang H.C., Kang L., Kim M., Kim S., et al. Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J. Am. Med. Dir. Assoc. 2020;21:300–307. doi: 10.1016/j.jamda.2019.12.012.
    1. Office of Internal Affairs, Health, Welfare and Labor Promote the 10-Year Long-Term Care Project 2.0. [(accessed on 29 September 2016)]; Available online: .
    1. Fielding R.A., Vellas B., Evans W.J., Bhasin S., Morley J.E., Newman A.B., Abellan van Kan G., Andrieu S., Bauer J., Breuille D., et al. Sarcopenia: An undiagnosed condition in older adults. Current consensus definition: Prevalence, etiology, and consequences. International working group on sarcopenia. J. Am. Med. Dir. Assoc. 2011;12:249–256. doi: 10.1016/j.jamda.2011.01.003.
    1. Kim Y., Park K.S., Yoo J.I. Associations between the quality of life in sarcopenia measured with the SarQoL® and nutritional status. Health Qual. Life Outcomes. 2021;19:1–7. doi: 10.1186/s12955-020-01619-2.
    1. Casuso R.A., Huertas J.R. The emerging role of skeletal muscle mitochondrial dynamics in exercise and ageing. Ageing Res. Rev. 2020;58:101025. doi: 10.1016/j.arr.2020.101025.
    1. Kong H.H., Won C.W., Kim W. Effect of sarcopenic obesity on deterioration of physical function in the elderly. Arch. Gerontol. Geriatr. 2020;89:104065. doi: 10.1016/j.archger.2020.104065.
    1. Cao L., Morley J.E. Sarcopenia is recognized as an independent condition by an international classification of disease, Tenth Revision, Clinical Modification (ICD-10-CM) Code. J. Am. Med. Dir. Assoc. 2016;17:675–677. doi: 10.1016/j.jamda.2016.06.001.
    1. Waite S.J., Maitland S., Thomas A., Yarnall A.J. Sarcopenia and frailty in individuals with dementia: A systematic review. Arch. Gerontol. Geriatr. 2021;92:104268. doi: 10.1016/j.archger.2020.104268.
    1. Chang K.-V., Hsu T.-H., Wu W.-T., Huang K.-C., Han D.-S. Is sarcopenia associated with depression? A systematic review and meta-analysis of observational studies. Age Ageing. 2017;46:738–746. doi: 10.1093/ageing/afx094.
    1. Arnau A., Espaulella J., Méndez T., Serrarols M., Canudas J., Formiga F., Ferrer M. Lower limb function and 10-year survival in population aged 75 years and older. Fam. Pract. 2016;33:10–16. doi: 10.1093/fampra/cmv088.
    1. Treacy D., Hassett L. The Short Physical Performance Battery. J. Physiother. 2018;64:61. doi: 10.1016/j.jphys.2017.04.002.
    1. Guralnik J.M., Simonsick E.M., Ferrucci L., Glynn R.J., Berkman L.F., Blazer D.G., Scherr P.A., Wallace R.B. A short physical performance battery assessing lower extremity function: Association with self-reported disability and prediction of mortality and nursing home admission. J. Gerontol. 1994;49:M85–M94. doi: 10.1093/geronj/49.2.M85.
    1. National Health Service, Ministry of Health and Welfare Taiwan Version Mini Nutritional Assessment Scale. [(accessed on 18 September 2018)]; Available online: .
    1. Huang C.-Y., Hwang A.-C., Liu L.-K., Lee W.-J., Chen L.-Y., Peng L.-N., Lin M.-H., Chen L.-K. Association of dynapenia, sarcopenia, and cognitive impairment among community-dwelling older Taiwanese. Rejuvenation Res. 2016;19:71–78. doi: 10.1089/rej.2015.1710.
    1. Phu S., Kirk B., Bani Hassan E., Vogrin S., Zanker J., Bernardo S., Duque G. The diagnostic value of the short physical performance battery for sarcopenia. BMC Geriatr. 2020;20:242. doi: 10.1186/s12877-020-01642-4.
    1. Reiss J., Iglseder B., Alzner R., Mayr-Pirker B., Pirich C., Kässmann H., Kreutzer M., Dovjak P., Reiter R. Consequences of applying the new EWGSOP2 guideline instead of the former EWGSOP guideline for sarcopenia case finding in older patients. Age Ageing. 2019;48:719–724. doi: 10.1093/ageing/afz035.
    1. Ryu M., Jo J., Lee Y., Chung Y.S., Kim K.M., Baek W.C. Association of physical activity with sarcopenia and sarcopenic obesity in community-dwelling older adults: The Fourth Korea National Health and Nutrition Examination Survey. Age Ageing. 2013;42:734–740. doi: 10.1093/ageing/aft063.
    1. Flöter A., Nathorst-Böös J., Carlström K., Ohlsson C., Ringertz H., Schoultz B. Effects of combined estrogen/testosterone therapy on bone and body composition in oophorectomized women. Gynecol. Endocrinol. 2005;20:155–160. doi: 10.1080/09513590400021193.
    1. Tu S., Chen J. Sarcopenia. Fam. Med. Prim. Care. 2017;32:154–159. doi: 10.6965/FMPMC.
    1. Maeda K., Koga T., Nasu T., Takaki M., Akagi J. Predictiveaccuracy of calf circumference measurements to detect decreased skeletal muscle mass and European Society for clinical nutrition and metabolism-defined malnutrition in hospitalized older patients. Ann. Nutr. Metab. 2017;71:10–15. doi: 10.1159/000478707.
    1. Ueshima J., Maeda K., Shimizu A., Inoue T., Murotani K., Mori N., Satake S., Matsui Y., Arai H. Diagnostic accuracy of sarcopenia by “possible sarcopenia” premiered by the Asian Working Group for Sarcopenia 2019 definition. Arch. Gerontol. Geriatr. 2021;97:104484. doi: 10.1016/j.archger.2021.104484.
    1. Landi F., Liperoti R., Fusco D., Mastropaolo S., Quattrociocchi D., Proia A., Russo A., Bernabei R., Onder G. Prevalence and risk factors of sarcopenia among nursing home older residents. J. Gerontol. A. 2011;67:48–55. doi: 10.1093/gerona/glr035.
    1. Zamboni M., Mazzali G., Fantin F., Rossi A., Di Francesco V. Sarcopenic obesity: A new category of obesity in the elderly. Nutr. Metab. Cardiovasc. Dis. 2008;18:388–395. doi: 10.1016/j.numecd.2007.10.002.
    1. Cheng Q., Zhu X., Zhang X., Li H., Du Y., Hong W., Xue S., Zhu H. A cross-sectional study of loss of muscle mass corresponding to sarcopenia in healthy Chinese men and women: Reference values, prevalence, and association with bone mass. J. Bone. Miner. Metab. 2014;32:78–88. doi: 10.1007/s00774-013-0468-3.
    1. De Cock A.-M., Perkisas S., Verhoeven V., Vandewoude M., Fransen E., Remmen R. The impact of cognitive impairment on the physical ageing process. Aging Clin. Exp. Res. 2018;30:1297–1306. doi: 10.1007/s40520-018-1016-8.
    1. Chang K.-V., Hsu T.-H., Wu W.-T., Huang K.-C., Han D.-S. Association between sarcopenia and cognitive impairment: A systematic review and meta-analysis. J. Am. Med. Dir. Assoc. 2016;17:1164.e7–1164.e15. doi: 10.1016/j.jamda.2016.09.013.
    1. Andrade-Moraes C.H., Oliveira-Pinto A.V., Castro-Fonseca E., da Silva C.G., Guimarães D.M., Szczupak D., Parente-Bruno D.R., Carvalho L.R., Polichiso L., Gomes B.V., et al. Cell number changes in Alzheimer’s disease relate to dementia, not to plaques and tangles. Brain. 2013;136:3738–3752. doi: 10.1093/brain/awt273.
    1. Maeda K., Akagi J. Cognitive impairment is independently associated with definitive and possible sarcopenia in hospitalized older adults: The prevalence and impact of comorbidities. Geriatr. Gerontol. Int. 2017;17:1048–1056. doi: 10.1111/ggi.12825.
    1. Herter T.M., Scott S.H., Dukelow S.P. Systematic changes in position sense accompany normal aging across adulthood. J. Neuroeng. Rehabil. 2014;11:43. doi: 10.1186/1743-0003-11-43.
    1. Grönstedt H., Vikström S., Cederholm T., Franzén E., Seiger Å., Wimo A., Faxén-Irving G., Boström A.-M. A study protocol of Older Person’s Exercise and Nutrition Study (OPEN)—a sit-to-stand activity combined with oral protein supplement—effects on physical function and independence: A cluster randomized clinical trial. BMC Geriatr. 2018;18:1–10. doi: 10.1186/s12877-018-0824-1.
    1. Gadelha A.B., Neri S.G.R., Oliveira R.J., Bottaro M., David A.C., Vainshelboim B., Lima R.M. Severity of sarcopenia is associated with postural balance and risk of falls in community-dwelling older women. Exp. Aging Res. 2018;44:258–269. doi: 10.1080/0361073X.2018.1449591.
    1. Yu J. The etiology and exercise implications of sarcopenia in the elderly. Int. J. Nurs. Sci. 2015;2:199–203. doi: 10.1016/j.ijnss.2015.04.010.
    1. Viswanathan A., Sudarsky L. Balance and gait problems in the elderly. Handb. Clin. Neurol. 2012;103:623–634. doi: 10.1016/b978-0-444-51892-7.00045-0.
    1. Osoba M.Y., Rao A.K., Agrawal S.K., Lalwani A.K. Balance and gait in the elderly: A contemporary review. Laryngoscope Investig. Otolaryngol. 2019;4:143–153. doi: 10.1002/lio2.252.
    1. Chronic Disease Prevention and Control Team, National Health Administration, Ministry of Health and Welfare How serious is the problem of old adults falling? [(accessed on 14 November 2019)]; Available online: .
    1. Figueiro M.G., Plitnick B., Rea M.S., Gras L.Z., Rea M.S. Lighting and perceptual cues: Effects on gait measures of older adults at high and low risk for falls. BMC Geriatr. 2011;11:49. doi: 10.1186/1471-2318-11-49.
    1. Wolfson L., Judge J., Whipple R., King M. Strength is a major factor in balance, gait, and the occurrence of falls. J. Gerontol. A Biol. Sci. Med. Sci. 1995;50:64–67. doi: 10.1093/gerona/50a.special_issue.64.
    1. Yang M., Hu X., Xie L., Zhang L., Zhou J., Lin J., Wang Y., Li Y., Han Z., Zhang D., et al. SARC-F for sarcopenia screening in community-dwelling older adults: Are 3 items enough? Medicine. 2018;97:e11726. doi: 10.1097/MD.0000000000011726.

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