Pain control after total knee arthroplasty: a randomized trial comparing local infiltration anesthesia and continuous femoral block

Fatin Affas, Eva-Britt Nygårds, Carl-Olav Stiller, Per Wretenberg, Christina Olofsson, Fatin Affas, Eva-Britt Nygårds, Carl-Olav Stiller, Per Wretenberg, Christina Olofsson

Abstract

Background and purpose: Pain after total knee arthroplasty (TKA) is usually severe, and epidural analgesia or femoral nerve block has been considered to be an effective pain treatment. Recently, local infiltration analgesia (LIA) has become increasingly popular but the outcome of this method regarding the analgesic effect has not been fully evaluated. We compared local infiltration analgesia and femoral block with regard to analgesia and morphine demand during the first 24 h after TKA.

Methods: 40 patients undergoing TKA under spinal anesthesia were randomized to receive femoral nerve block (group F) or peri- and intraarticular infiltration analgesia (group LIA) with a mixture containing ropivacaine, ketorolac, and epinephrine. All patients had access to intravenous patient-controlled analgesia (PCA) with morphine postoperatively. Pain intensity at rest and upon movement was assessed on a numeric rating scale (0-10) on an hourly basis over 24 h if the patients were awake.

Results: The average pain at rest was marginally lower with LIA (1.6) than with femoral block (2.2). Total morphine consumption per kg was similar between the 2 groups. Ancillary analysis revealed that 1 of 20 patients in the LIA group reported a pain intensity of > 7 upon movement, as compared to 7 out of 19 in the femoral block group (p = 0.04).

Interpretation: Both LIA and femoral block provide good analgesia after TKA. LIA may be considered to be superior to femoral block since it is cheaper and easier to perform.

Figures

Figure 1.
Figure 1.
Average pain score (NRS) at rest and upon movement over 24 h after surgery. If the patient was sleeping, no data were recorded (n = 20 in each group).
Figure 2.
Figure 2.
Average morphine use (PCA) in mg for the 2 groups during the first 24 h after surgery (n = 20 in each group).

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