The brief negative symptom scale: psychometric properties

Brian Kirkpatrick, Gregory P Strauss, Linh Nguyen, Bernard A Fischer, David G Daniel, Angel Cienfuegos, Stephen R Marder, Brian Kirkpatrick, Gregory P Strauss, Linh Nguyen, Bernard A Fischer, David G Daniel, Angel Cienfuegos, Stephen R Marder

Abstract

The participants in the NIMH-MATRICS Consensus Development Conference on Negative Symptoms recommended that an instrument be developed that measured blunted affect, alogia, asociality, anhedonia, and avolition. The Brief Negative Symptom Scale (BNSS) is a 13-item instrument designed for clinical trials and other studies that measures these 5 domains. The interrater, test-retest, and internal consistency of the instrument were strong, with respective intraclass correlation coefficients of 0.93 for the BNSS total score and values of 0.89-0.95 for individual subscales. Comparisons with positive symptoms and other negative symptom instruments supported the discriminant and concurrent validity of the instrument.

References

    1. Kraepelin E. Dementia Praecox and Paraphrenia. Translated by R.M. Barclay. Huntington, NY: Robert E. Krieger Publishing Co., Inc; 1971.
    1. Strauss JS, Carpenter WT, Jr., Bartko JJ. The diagnosis and understanding of schizophrenia. Part III. Speculations on the processes that underlie schizophrenic symptoms and signs. Schizophr Bull. 1974 Winter(11):61–69.
    1. Crow TJ. The two-syndrome concept: origins and current status. Schizophr Bull. 1985;11:471–486.
    1. Andreasen NC. The Scale for the Assessment of Negative Symptoms (SANS): conceptual and theoretical foundations. Br J Psychiatry Suppl. 1989;7:49–58.
    1. Axelrod BN, Goldman RS, Alphs LD. Validation of the 16-item Negative Symptom Assessment. J Psychiatr Res. 1993;27:253–258.
    1. Axelrod BN, Goldman RS, Woodard JL, Alphs LD. Factor structure of the negative symptom assessment. Psychiatry Res. 1994;52(2):173–179.
    1. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull. 1987;13:261–276.
    1. Kirkpatrick B, Fenton WS, Carpenter WT, Jr., Marder SR. The NIMH-MATRICS consensus statement on negative symptoms. Schizophr Bull. 2006;32:214–219.
    1. Chan RCK, Wang Y, Huang J, et al. Anticipatory and consummatory components of the experience of pleasure in schizophrenia: cross-cultural validation and extension. Psychiatry Res. 2010;175(1–2):181–183.
    1. Gard DE, Gard MG, Kring AM, John OP. Anticipatory and consummatory components of the experience of pleasure: a scale development study. J Res Pers. 2006;40:1086–1102.
    1. Gard DE, Kring AM, Gard MG, Horan WP, Green MF. Anhedonia in schizophrenia: distinctions between anticipatory and consummatory pleasure. Schizophr Res. 2007;93:253–260.
    1. Buchanan RW, Carpenter WT. Domains of psychopathology: an approach to the reduction of heterogeneity in schizophrenia. J Nerv Ment Dis. 1994;182(4):193–204.
    1. Guy W. US Department of Health, Education and Welfare. Washington, DC: National Institute of Mental Health; 1976. ECDEU assessment manual for psychopharmacology; pp. 76–338.
    1. Kirkpatrick B, Buchanan RW, McKenney PD, Alphs LD, Carpenter WT., Jr. The Schedule for the Deficit Syndrome: an instrument for research in schizophrenia. Psychiatry Res. 1989;30:119–123.
    1. Wechsler D. Wechsler Abbreviated Scale of Intelligence. San Antonio, TX: Psychological Corporation; 1999.
    1. Blanchard JJ, Cohen AS. The structure of negative symptoms within schizophrenia: implications for assessment. Schizophr Bull. 2006;32:238–245.
    1. Chemerinski E, Reichenberg A, Kirkpatrick B, Bowie CR, Harvey PD. Three dimensions of clinical symptoms in elderly patients with schizophrenia: prediction of six-year cognitive and functional status. Schizophr Res. 2006;85:12–19.
    1. Dickerson F, Kirkpatrick B, Boronow J, et al. Deficit schizophrenia: association with serum antibodies to cytomegalovirus. Schizophr Bull. 2006;32:396–400.
    1. Kirkpatrick B, Amador XF, Yale SA, et al. The deficit syndrome in the DSM-IV Field Trial: II. Depressive episodes and persecutory beliefs. Schizophr Res. 1996;20:79–90.
    1. Kirkpatrick B, Amador XF, Yale SA, et al. The deficit syndrome in the DSM-IV Field Trial: I. Alcohol and other drug abuse. Schizophr Res. 1996;20:69–77.
    1. Kirkpatrick B, Buchanan RW, Breier A, Carpenter WT. Case identification and stability of the deficit syndrome of schizophrenia. Psychiatry Res. 1993;47:47–56.
    1. Kirkpatrick B, Castle D, Murray RM, Carpenter WT., Jr. Risk factors for the deficit syndrome of schizophrenia. Schizophr Bull. 2000;26:233–242.
    1. Kirkpatrick B, Fernandez-Egea E, Garcia-Rizo C, Bernardo M. Differences in glucose tolerance between deficit and nondeficit schizophrenia. Schizophr Res. 2009;107(2–3):122–127.
    1. Kirkpatrick B, Herrera Castanedo S, Vazquez-Barquero JL. Summer birth and deficit schizophrenia: Cantabria, Spain. J Nerv Ment Dis. 2002;190:526–532.
    1. Kirkpatrick B, Ram R, Amador X, et al. Summer birth and the deficit syndrome of schizophrenia. Am J Psychiatry. 1998;155:1221–1226.
    1. Kirkpatrick B, Ram R, Bromet E. The deficit syndrome in the Suffolk County Mental Health Project. Schizophr Res. 1996;22:119–126.
    1. Kirkpatrick B, Tek C, Kelly C, Allardyce J, Morrison G, McCreadie RG. Summer birth and deficit schizophrenia: Dumfries and Galloway, Southwest Scotland. Am J Psychiatry. 2002;150:1382–1387.
    1. Messias E, Kirkpatrick B, Bromet E, et al. Summer birth and deficit schizophrenia: a pooled analysis from 6 countries. Arch Gen Psychiatry. 2004;61:985–989.
    1. Messias E, Kirkpatrick B. Summer birth and the deficit syndrome of schizophrenia in the epidemiological catchment area study. J Nerv Ment Dis. 2001;189:608–612.
    1. Messias EM, Tek C, Kirkpatrick B. Substance abuse and the heterogeneity of schizophrenia: a population-based study. Schizophr Res. 2003;62:293–294.
    1. Tek C, Kirkpatrick B, Kelly C, McCreadie RG. Summer birth and deficit schizophrenia in Nithsdale, Scotland. J Nerv Ment Dis. 2001;189:613–617.
    1. Wang X, Yao S, Kirkpatrick B, Shi C, Yi J. Psychopathology and neuropsychological impairments in deficit and nondeficit schizophrenia of Chinese origin. Psychiatry Res. 2008;158(2):195–205.
    1. Kirkpatrick B, Buchanan RW, Ross DE, Carpenter WT. A separate disease within the syndrome of schizophrenia. Arch Gen Psychiatry. 2001;58:165–171.
    1. Laughren T, Levin R. Food and Drug Administration perspective on negative symptoms in schizophrenia as a target for a drug treatment claim. Schizophr Bull. 2006;32:220–222.

Source: PubMed

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