Multiple Sclerosis Impact Scale (MSIS-29): reliability and validity in hospital based samples
A Riazi, J C Hobart, D L Lamping, R Fitzpatrick, A J Thompson, A Riazi, J C Hobart, D L Lamping, R Fitzpatrick, A J Thompson
Abstract
Background and aim: The psychometric properties of rating scales are sample dependent and need evaluations in different samples. The Multiple Sclerosis Impact Scale (MSIS-29), a new patient based rating scale for multiple sclerosis (MS) was predominantly developed from a community based sample derived from the MS Society. A number of important patient characteristics of this sample remain unknown. The aim of the study was to evaluate five psychometric properties of the MSIS-29 in three hospital based samples: people admitted for rehabilitation, people admitted for intravenous corticosteroid treatment for MS relapses, and people with primary progressive MS.
Methods: People with MS were recruited from the three clinical settings. They completed several health measures. MSIS-29 data were evaluated for data quality, scaling assumptions, acceptability, reliability and validity, and compared with those from a previously reported community based study.
Results: A total of 233 people (rehabilitation p=53; corticosteroids p=76; primary progressive p=104) completed questionnaires. In all samples, missing data were low (<or=2.2%), scaling assumptions were satisfied, and reliability was high (>or=0.91). Correlations between the MSIS-29 and other scales were consistent with a priori hypotheses. Findings were consistent with those from the community samples.
Conclusions: The psychometric properties of the MSIS-29 are consistent across three hospital based samples, and similar to those in the community samples. These findings further support its use as an outcome measure in different clinical settings.
References
- Brain. 2000 May;123 ( Pt 5):1027-40
- Brain. 2001 May;124(Pt 5):962-73
- Neurology. 2001 Aug 28;57(4):639-44
- Psychol Med. 1979 Feb;9(1):139-45
- Br J Med Psychol. 1998 Mar;71 ( Pt 1):99-106
- Med Care. 1988 Jul;26(7):724-35
- Med Care. 1994 Jan;32(1):40-66
- Neurology. 1996 Jul;47(1):129-39
- Brain. 1997 Jun;120 ( Pt 6):1085-96
- Neurology. 1983 Nov;33(11):1444-52
Source: PubMed