Clevudine myopathy in patients with chronic hepatitis B
Byung Kook Kim, Jeeyoung Oh, So Young Kwon, Won Hyeok Choe, Soon Young Ko, Kyoung Hoon Rhee, Tae Ho Seo, So Dug Lim, Chang Hong Lee, Byung Kook Kim, Jeeyoung Oh, So Young Kwon, Won Hyeok Choe, Soon Young Ko, Kyoung Hoon Rhee, Tae Ho Seo, So Dug Lim, Chang Hong Lee
Abstract
Clevudine (L-FMAU) is a thymidine l-nucleoside analogue that was recently introduced for the treatment of chronic hepatitis B virus infection. Previous studies showed that clevudine has potent and sustained antiviral activity without causing viral resistance. No severe adverse event occurred during clinical trials. We describe two cases of drug-induced myopathy during long-term treatment of chronic hepatitis B with clevudine.
Source: PubMed