Association between feeding difficulties and language delay in preterm infants using Bayley Scales of Infant Development-Third Edition
Ira Adams-Chapman, Carla M Bann, Yvonne E Vaucher, Barbara J Stoll, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, Alan H Jobe, Michael S Caplan, William Oh, Abbot R Laptook, Betty R Vohr, Angelita M Hensman, Bonnie E Stephens, Barbara Alksninis, Dawn Andrews, Kristen Angela, Bill Cashore, Kim Francis, Regina A Gargus, Dan Gingras, Shabnam Lainwala, Theresa M Leach, Martha R Leonard, James R Moore, Lucy Noel, Rachel V Walden, Victoria E Watson, Avroy A Fanaroff, Michele C Walsh, Deanne E Wilson-Costello, Nancy S Newman, Bonnie S Siner, Harriet G Friedman, Kurt Schibler, Edward F Donovan, Jean J Steichen, Kate Bridges, Barbara Alexander, Cathy Grisby, Holly L Mincey, Jody Hessling, Teresa L Gratton, Marcia Worley Mersmann, Kimberly Yolton, Ronald N Goldberg, C Michael Cotten, Ricki F Goldstein, Kathy J Auten, Kimberley A Fisher, Katherine A Foy, Sandra Grimes, Kathryn E Gustafson, Melody B Lohmeyer, David P Carlton, Ellen C Hale, Linda Black, Sheena Carter, Elisabeth Dinkins, Sobha Fritz, Judson Miller, Maureen Mulligan LaRossa, Irma Seabrook, Gloria V Smikle, Rosemary D Higgins, Stephanie Wilson Archer, Ivan D Frantz 3rd, John M Fiascone, Paige T Church, Brenda L MacKinnon, Ellen Nylen, Anne Furey, Elisabeth C McGowan, Brenda B Poindexter, James A Lemons, Anna M Dusick, Dianne E Herron, Leslie Dawn Wilson, Jessica Bissey, Ann B Cook, Greg Eaken, Faithe Hamer, Carolyn Lytle, Heike M Minnich, Abhik Das, W Kenneth Poole, Dennis Wallace, Jeanette O'Donnell Auman, Margaret Cunningham, Amanda R Irene, Jamie E Newman, Carolyn M Petrie Huitema, James W Pickett 2nd, Scott E Schaefer, Kristin M Zaterka-Baxter, Krisa P Van Meurs, David K Stevenson, Marian M Adams, Susan R Hintz, M Bethany Ball, Joan M Baran, Ginger K Brudos, Maria Elena DeAnda, Anne M DeBattista, Jean G Kohn, Carol G Kuelper, Renee P Pyle, Dharshi Sivakumar, Waldemar A Carlo, Namasivayam Ambalavanan, Myriam Peralta-Carcelen, Amanda Soong, Monica V Collins, Shirley S Cosby, Vivien A Phillips, Kirstin J Bailey, Fred J Biasini, Stephanie A Chopko, Kristen C Johnston, Kathleen G Nelson, Cryshelle S Patterson, Richard V Rector, Sally Whitley, Neil N Finer, Maynard R Rasmussen, Paul R Wozniak, Martha G Fuller, Kathy Arnell, Renee Bridge, Clarence Demetrio, Donna Posin, Wade Rich, Edward F Bell, Michael J Acarregui, Karen J Johnson, Diane L Eastman, Charles R Bauer, Shahnaz Duara, Ruth Everett-Thomas, Maria Calejo, Alexis N Diaz, Silvia M Frade Eguaras, Andrea Garcia, Kasey Hamlin-Smith, Michelle Harwood, Sylvia Hiriart-Fajardo, Elaine O Mathews, Helina Pierre, Arielle Riguard, Alexandra Stroerger, Kristi L Watterberg, Robin K Ohls, Conra Backstrom Lacy, Julie Rohr, Janell Fuller, Jean Lowe, Rebecca Montman, Dale L Phelps, Gary J Myers, Linda J Reubens, Erica Burnell, Julie Babish Johnson, Cassandra A Horihan, Diane Hust, Rosemary L Jensen, Emily Kushner, Joan Merzbach, Lauren Zwetsch, Kelley Yost, Pablo J Sánchez, Charles R Rosenfeld, Walid A Salhab, Roy J Heyne, Alicia Guzman, Gaynelle Hensley, Nancy A Miller, Elizabeth Heyne, Linda A Madden, Sally Adams, Janet S Morgan, Catherine Twell Boatman, Lyndon Baines Johnson, Kathleen A Kennedy, Jon E Tyson, Esther G Akpa, Nora I Alaniz, Anna E Lis, Charles Green, Sarah Martin, Georgia E McDavid, Patti L Pierce Tate, Maegan C Simmons, Susan Dieterich, Patricia W Evans, Brenda H Morris, Stacey Reddoch, Saba Siddiki, Sharon L Wright, Roger G Faix, Bradley A Yoder, Karen A Osborne, Jennifer J Jensen, Cynthia Spencer, Kimberlee Weaver-Lewis, Anna Bodnar, R Karena Strong, T Michael O'Shea, Nancy J Peters, Carroll Peterson, Ellen L Waldrep, Lisa K Washburn, Robert G Dillard, Cherrie D Welch, Melissa Whalen Morris, Gail Wiley Hounshell, Seetha Shankaran, Athina Pappas, Rebecca Bara, Geraldine Muran, Laura Goldston, Richard A Ehrenkranz, Christine G Butler, Harris Jacobs, Patricia Cervone, Patricia Gettner, Sheila Greisman, Monica Konstantino, JoAnn Poulsen, Janet Taft, Joanne Williams, Nancy Close, Walter Gilliam, Elaine Romano, Ira Adams-Chapman, Carla M Bann, Yvonne E Vaucher, Barbara J Stoll, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, Alan H Jobe, Michael S Caplan, William Oh, Abbot R Laptook, Betty R Vohr, Angelita M Hensman, Bonnie E Stephens, Barbara Alksninis, Dawn Andrews, Kristen Angela, Bill Cashore, Kim Francis, Regina A Gargus, Dan Gingras, Shabnam Lainwala, Theresa M Leach, Martha R Leonard, James R Moore, Lucy Noel, Rachel V Walden, Victoria E Watson, Avroy A Fanaroff, Michele C Walsh, Deanne E Wilson-Costello, Nancy S Newman, Bonnie S Siner, Harriet G Friedman, Kurt Schibler, Edward F Donovan, Jean J Steichen, Kate Bridges, Barbara Alexander, Cathy Grisby, Holly L Mincey, Jody Hessling, Teresa L Gratton, Marcia Worley Mersmann, Kimberly Yolton, Ronald N Goldberg, C Michael Cotten, Ricki F Goldstein, Kathy J Auten, Kimberley A Fisher, Katherine A Foy, Sandra Grimes, Kathryn E Gustafson, Melody B Lohmeyer, David P Carlton, Ellen C Hale, Linda Black, Sheena Carter, Elisabeth Dinkins, Sobha Fritz, Judson Miller, Maureen Mulligan LaRossa, Irma Seabrook, Gloria V Smikle, Rosemary D Higgins, Stephanie Wilson Archer, Ivan D Frantz 3rd, John M Fiascone, Paige T Church, Brenda L MacKinnon, Ellen Nylen, Anne Furey, Elisabeth C McGowan, Brenda B Poindexter, James A Lemons, Anna M Dusick, Dianne E Herron, Leslie Dawn Wilson, Jessica Bissey, Ann B Cook, Greg Eaken, Faithe Hamer, Carolyn Lytle, Heike M Minnich, Abhik Das, W Kenneth Poole, Dennis Wallace, Jeanette O'Donnell Auman, Margaret Cunningham, Amanda R Irene, Jamie E Newman, Carolyn M Petrie Huitema, James W Pickett 2nd, Scott E Schaefer, Kristin M Zaterka-Baxter, Krisa P Van Meurs, David K Stevenson, Marian M Adams, Susan R Hintz, M Bethany Ball, Joan M Baran, Ginger K Brudos, Maria Elena DeAnda, Anne M DeBattista, Jean G Kohn, Carol G Kuelper, Renee P Pyle, Dharshi Sivakumar, Waldemar A Carlo, Namasivayam Ambalavanan, Myriam Peralta-Carcelen, Amanda Soong, Monica V Collins, Shirley S Cosby, Vivien A Phillips, Kirstin J Bailey, Fred J Biasini, Stephanie A Chopko, Kristen C Johnston, Kathleen G Nelson, Cryshelle S Patterson, Richard V Rector, Sally Whitley, Neil N Finer, Maynard R Rasmussen, Paul R Wozniak, Martha G Fuller, Kathy Arnell, Renee Bridge, Clarence Demetrio, Donna Posin, Wade Rich, Edward F Bell, Michael J Acarregui, Karen J Johnson, Diane L Eastman, Charles R Bauer, Shahnaz Duara, Ruth Everett-Thomas, Maria Calejo, Alexis N Diaz, Silvia M Frade Eguaras, Andrea Garcia, Kasey Hamlin-Smith, Michelle Harwood, Sylvia Hiriart-Fajardo, Elaine O Mathews, Helina Pierre, Arielle Riguard, Alexandra Stroerger, Kristi L Watterberg, Robin K Ohls, Conra Backstrom Lacy, Julie Rohr, Janell Fuller, Jean Lowe, Rebecca Montman, Dale L Phelps, Gary J Myers, Linda J Reubens, Erica Burnell, Julie Babish Johnson, Cassandra A Horihan, Diane Hust, Rosemary L Jensen, Emily Kushner, Joan Merzbach, Lauren Zwetsch, Kelley Yost, Pablo J Sánchez, Charles R Rosenfeld, Walid A Salhab, Roy J Heyne, Alicia Guzman, Gaynelle Hensley, Nancy A Miller, Elizabeth Heyne, Linda A Madden, Sally Adams, Janet S Morgan, Catherine Twell Boatman, Lyndon Baines Johnson, Kathleen A Kennedy, Jon E Tyson, Esther G Akpa, Nora I Alaniz, Anna E Lis, Charles Green, Sarah Martin, Georgia E McDavid, Patti L Pierce Tate, Maegan C Simmons, Susan Dieterich, Patricia W Evans, Brenda H Morris, Stacey Reddoch, Saba Siddiki, Sharon L Wright, Roger G Faix, Bradley A Yoder, Karen A Osborne, Jennifer J Jensen, Cynthia Spencer, Kimberlee Weaver-Lewis, Anna Bodnar, R Karena Strong, T Michael O'Shea, Nancy J Peters, Carroll Peterson, Ellen L Waldrep, Lisa K Washburn, Robert G Dillard, Cherrie D Welch, Melissa Whalen Morris, Gail Wiley Hounshell, Seetha Shankaran, Athina Pappas, Rebecca Bara, Geraldine Muran, Laura Goldston, Richard A Ehrenkranz, Christine G Butler, Harris Jacobs, Patricia Cervone, Patricia Gettner, Sheila Greisman, Monica Konstantino, JoAnn Poulsen, Janet Taft, Joanne Williams, Nancy Close, Walter Gilliam, Elaine Romano
Abstract
Objective: To evaluate the relationship between abnormal feeding patterns and language performance on the Bayley Scales of Infant Development-Third Edition at 18-22 months adjusted age among a cohort of extremely premature infants.
Study design: This is a descriptive analysis of 1477 preterm infants born ≤ 26 weeks gestation or enrolled in a clinical trial between January 1, 2006 and March 18, 2008 at a National Institute of Child Health and Human Development Neonatal Research Network center who completed the 18-month neurodevelopmental follow-up assessment. At 18-22 months adjusted age, a comprehensive neurodevelopmental evaluation was performed by certified examiners including the Receptive and Expressive Language Subscales of the Bayley Scales of Infant Development-Third Edition and a standardized adjusted age feeding behaviors and nutritional intake. Data were analyzed using bivariate and multilevel linear and logistic regression modeling.
Results: Abnormal feeding behaviors were reported in 193 (13%) of these infants at 18-22 months adjusted age. Abnormal feeding patterns, days of mechanical ventilation, hearing impairment, and Gross Motor Functional Classification System level ≥ 2 each independently predicted lower composite language scores.
Conclusions: At 18 months adjusted age, premature infants with a history of feeding difficulties are more likely to have language delay. Neuromotor impairment and days of mechanical ventilation are both important risk factors associated with these outcomes.
Keywords: BSID-III; Bayley Scales of Infant Development-Third Edition; ELBW; Extremely low birth weight; GMFCS; Gross Motor Functional Classification System; IVH; Intraventricular hemorrhage; MRI; Magnetic resonance imaging; ND; NEC; NICHD; NRN; National Institute of Child Health and Human Development; Necrotizing enterocolitis; Neonatal Research Network; Neurodevelopmental; PVL; Periventricular leukomalacia.
Conflict of interest statement
The authors declare no conflicts of interest.
Copyright © 2013 Mosby, Inc. All rights reserved.
Source: PubMed