Effect of Multi-sensory Stimulation on Neuromuscular Development of Premature Infants: A Randomized Clinical Trial

Hossein Zeraati, Fatemeh Nasimi, Akram Rezaeian, Javad Shahinfar, Maryam Ghorban Zade, Hossein Zeraati, Fatemeh Nasimi, Akram Rezaeian, Javad Shahinfar, Maryam Ghorban Zade

Abstract

Objectives: Preterm birth is considered as a risk factor for developmental disabilities, which can lead to long-term effects on the nervous system of children. The aim of this study was to determine the effect of multi-sensory stimulation on neurodevelopment of premature infants.

Materials and methods: In this two-group double-blind clinical trial in Jahrom Hospital, Jahrom, Iran from Jun to Aug 2016, 80 preterm infants were randomly divided. The intervention group received multisensory stimulation for 12 min per session, 5 sessions per wk along with routine NICU care and the control group received ward's routine care. Neuromuscular maturity for each infant was assessed by New Ballard Score. Data were analyzed using independent t-test.

Results: Based on ANOVA with repeated measures, New Ballard score significantly changed in the intervention group before and after intervention (P= 0.001). This change was also significant in the control group (P=0. 04). However, the changes in New Ballard score were significantly different before and after intervention between the two groups (P=0.001).

Conclusion: Multi-sensory stimulation can have beneficial effects on the development of neuromuscular in premature infants.

Keywords: Multisensory-stimulation; Neurodevelopment; New Ballard scale; Premature infants.

Conflict of interest statement

The authors declare that there is no conflict of interest.

References

    1. William W, Hay Myron, Levin J, Robin R, Mark J. Current pediatric diagnisis and treatment. 15th ed. McGraw Hill Professional; 2005.
    1. Lodygensky GA, Seghier ML, Warfield SK, Tolsa CB, Sizonenko S, Lazeyras F, et al. Intrauterine growth restriction affects the preterm infant’s hippocampus. Pediatr Res. 2008;63(4):438–443.
    1. Nasimi F, Zeraati H, Shahinfar J, Boskabadi H, Ghorbanzade M. The effect of multisensory stimulation on weight gain of preterm infants. Journal of Babol University of Medical Sciences. 2016 Dec;18(12):13–8.
    1. Lester BM, Miller RJ, Hawes K, Salisbury A, Bigsby R, Sullivan MC, et al. Infant Neurobehavioral Development. Semin Perinatol. 2011;35(1):8–19.
    1. Tolsa CB, Zimine S, Warfield SK, Freschi M, Sancho Rossignol A, Lazeyras F, et al. Early alteration of structural and functional brain development in premature infants born with intrauterine growth restriction. Pediatr Res. 2004;56(1):132–138.
    1. Lodygensky GA, Seghier ML, Warfield SK, Tolsa CB, Sizonenko S, Lazeyras F, et al. Intrauterine growth restriction affects the preterm infant’s hippocampus. Pediatr Res. 2008;63(4):438–443.
    1. Fanaroff AA, Martin RJ. Neonatal-perinatal medicine: diseases of the fetus and infant. In: Timothy E, Lozte , Geoffrey Miller, editors. Hypotonia and neumuscular. Elsevier Health Sciences; 2010. p. 997.
    1. Lekskulchai R, Cole J. Effect of a developmental program on motor performance in infants born preterm. Aust J Physiother. 2001;47(3):169–176.
    1. Kanagasabai PS, Mohan D, Lewis LE, Kamath A, Rao BK. Effect of Multisensory Stimulation on Neuromotor Development in Preterm Infants. Indian J Pediatr. 2013;80(6):460–464.
    1. Vandenberg KA. Individualized developmental care for high risk newborns in the NICU: A practice guideline. Early Human Development. 2007;83:433–442.
    1. Standley JM. The effect of music and multimodal stimulation on responses of premature infants in neonatal intensive care. Pediatr Nurs. 1998;24(6):532–8.
    1. Vaivre-Douret L, Oriot D, Blossier P, Py A, Kasolter-Péré M, Zwang J. The effect of multimodal stimulation and cutaneous application of vegetable oils on neonatal development in preterm infants: a randomized controlled trial. Child Care Health Dev. 2009;35(1):96–105.
    1. Javadifar N, Faal SH, Tadayon M, Dehdashtian M, Latify SM. The effect of massage with coconut oil on weight gain in preterm neonate. Sci Med J. 2009;8(2):247–54.
    1. Brown J, LaRossa M, Aylward G, Davis D, Rutherford P, Bakeman R. Nursery-based intervention with prematurely born babies and their mothers: are there effects? J Pediatr. 1980;97(3):487–91.
    1. White-Traut RC, Nelson MN, Silvestri JM, Patel M, Vasan U, Han BK, et al. Developmental intervention for preterm infants diagnosed with periventricular leukomalacia. Res Nurs Health. 1999;22(2):131–43.
    1. Vohr BR, Wright LL, Dusick AM, Mele L, Verter J, Steichen JJ, et al. Neurodevelopmental and functional outcomes of extremely low birth weight infants in the National Institute of Child Health and Human Development Neonatal Research Network. Pediatrics. 2005;105(6):1216–26.
    1. Sajedi F, Vameghi R, Mohseni Bandpei MA, Alizad V, Hemmati Gorgani S, Shahshahani Pour S. Motor developmental delay in 7500 Iranian infants: Prevalence and risk factors. Iran J Child Neurol. 2009;3(3):43–50.
    1. Modi N, Glover J. Massage therapy for preterm infants. Paper presented at Touch Research Symposium; Providence, Rhode Island . 2000.
    1. Taneja V, Sriram S, Beri RS, Sreenivas V, Aggarwal R, Kaur R. Not by bread alone: Impact of a structured 90-minute play session on development of children in an orphanage. Child Care Health Dev. 2002;28(1):95–100.

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