The Efficacy of Psychological Therapies in Reducing Weight and Binge Eating in People with Bulimia Nervosa and Binge Eating Disorder Who Are Overweight or Obese-A Critical Synthesis and Meta-Analyses

Marly Amorim Palavras, Phillipa Hay, Celso Alves Dos Santos Filho, Angélica Claudino, Marly Amorim Palavras, Phillipa Hay, Celso Alves Dos Santos Filho, Angélica Claudino

Abstract

Recurrent binge eating episodes, the core feature of Bulimia Nervosa (BN) and Binge Eating Disorder (BED), are frequently comorbid with obesity. Psychological interventions, notably Cognitive Behavioural Therapy (CBT), are effective for binge eating reduction in BED or BN but less so for weight loss. Behavioural Weight Loss Therapy (BWLT) shows effectiveness for binge eating reduction and weight loss but the latter appears poorly sustained over time. Our aim was to review evidence for efficacy of psychological therapies for BN/BED associated with overweight or obesity in reducing binge frequency and weight. A systematic search for randomized controlled trials with adult samples who had BN or BED was conducted considering articles in English, French, Spanish and Portuguese with no restrictions for the timeline publication ending in March 2016. A quality appraisal of the trials and meta-analyses comparing BWLT to CBT were done. This review identified 2248 articles for screening and 19 published articles were selected. No trials of BN were identified. This review found CBT was favoured compared to BWLT with regard to short-term binge eating reduction. However, insufficient evidence was found for superiority for BWLT efficacy compared to CBT considering binge eating remission, reduction of binge eating frequency and weight loss. More research is needed to test the efficacy of psychological treatments for BED or BN with co-morbid overweight or obesity, including trials evaluating binge eating remission and weight loss in the long-term.

Keywords: binge eating; obesity; psychotherapy; weight management.

Conflict of interest statement

In the past PH, has received reimbursement of expenses for speaking at medical meetings and attending symposia from Astra-Zeneca, Solvay Pharmaceuticals, Bristol-Myers Squibb, and Pfizer Pharmaceuticals, and for educational training for family doctors from Bristol-Myers Squibb, Pfizer Pharmaceuticals and Lundbeck and has been funded by Jansen-Cilag to attend educational symposia (none since 2004). PH receives royalties from Hogrefe and Huber, McGraw Hill Education, Blackwell Scientific Publications, Routledge, Australian Doctor, and BMJ Pubs, for publications on Eating Disorders. She receives or has received honoraria from Biomed Central and PLOS Medicine for Editorial duties. PH is an author on six studies cited in this review. AMC received reimbursement of expenses for attending medical conferences from Lundbeck and Eli-Lilly in the past (none since 2010). MAP participated in one meeting of an advisory board for the treatment of Binge Eating Disorder at Shire Pharmaceuticals, São Paulo, Brazil in 2016.

Figures

Figure 1
Figure 1
Prisma flow chart of study inclusion.
Figure 2
Figure 2
Behavioural Weight Loss Therapy versus Cognitive Behavioural Therapy-Effects on binge eating frequency at the end of treatment in individuals with binge eating disorder.

References

    1. Mitchison D., Hay P., Slewa-Younan S., Mond J. The changing demographic profile of eating disorder behaviors in the community. BMC Public Health. 2014;11:11. doi: 10.1186/1471-2458-14-943.
    1. Smink F.R., van Hoeken D., Hoek H.W. Epidemiology, course, and outcome of eating disorders. Curr. Opin. Psychiatry. 2013;26:543–548. doi: 10.1097/YCO.0b013e328365a24f.
    1. Hay P., Girosi F., Mond J. Prevalence and sociodemographic correlates of DSM-5 eating disorders in the Australian population. J. Eat. Disord. 2015;25:3–19. doi: 10.1186/s40337-015-0056-0.
    1. Qian J., Hu Q., Wan Y., Li T., Wu M., Ren Z., Yu D. Prevalence of eating disorders in the general population: A systematic review. Shanghai Arch. Psychiatry. 2013;25:212–223.
    1. American Psychiatric Association APA . Diagnostic and Statistical Manual of Mental Disorders. 5th ed. American Psychiatric Association; Washington, DC, USA: 2013.
    1. Johnson J.G., Spitzer R.L., Williams J.B. Health problems, impairment and illnesses associated with bulimia nervosa and binge eating disorder among primary care and obstetric gynaecology patients. Psychol. Med. 2001;31:1455–1466. doi: 10.1017/S0033291701004640.
    1. Darby A., Hay P., Mond J., Quirk F., Buttner P., Kennedy L. The rising prevalence of comorbid obesity and eating disorder behaviors from 1995 to 2005. Int. J. Eat. Disord. 2009;42:104–108. doi: 10.1002/eat.20601.
    1. Mond J.M., Hay P.J., Paxton S.J., Rodgers B., Darby A., Nillson J., Quirk F., Owen C. Eating disorders “mental health literacy” in low risk, high risk and symptomatic women: Implications for health promotion programs. Eat. Disord. 2010;18:267–285. doi: 10.1080/10640266.2010.490115.
    1. NCD Risk Factor Collaboration (NCD-RisC) Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1698 population-based measurement studies with 19.2 million participants. Lancet. 2016;2:1377–1396.
    1. Mitchell J.E., Devlin M.J., de Zwaan M., Crow S.J., Peterson C.B. Binge-Eating Disorder: Clinical Foundations and Treatment. 1st ed. The Guilford Press; New York, NY, USA: 2008. pp. 23–34.
    1. Bulik C.M., Marcus M.D., Zerwas S., Levine M.D., La Via M. The changing “weightscape” of bulimia nervosa. Am. J. Psychiatry. 2012;169:1031–1036. doi: 10.1176/appi.ajp.2012.12010147.
    1. Hudson J.I., Hiripi E., Pope H.G., Jr., Kessler R.C. The prevalence and correlates of eating disorders in the National Comorbidity Survey Replication. Biol. Psychiatry. 2007;61:348–358. doi: 10.1016/j.biopsych.2006.03.040.
    1. Clinical Practice Guidelines for the Management of Overweight and Obesity in Adults, Adolescents and Children in Australia. [(accessed on 4 December 2016)]; Available online: .
    1. Hay P. A systematic review of evidence for psychological treatments in eating disorders: 2005–2012. Int. J. Eat. Disord. 2013;46:462–469. doi: 10.1002/eat.22103.
    1. Da Luz F.Q., Hay P., Gibson A.A., Touyz S.W., Swinbourne J.M., Roekenes J.A., Sainsbury A. Does severe dietary energy restriction increase binge eating in overweight or obese individuals? A systematic review. Obes. Rev. 2015;16:652–665. doi: 10.1111/obr.12295.
    1. McElroy S.L., Guerdjikova A.I., Mori N., Munoz M.R., Keck P.E., Jr. Overview of the treatment of binge eating disorder. CNS Spectrum. 2015;20:546–556. doi: 10.1017/S1092852915000759.
    1. Wilson G.T., Wilfley D.E., Agras S., Bryson S.W. Psychological treatments of binge eating disorder. Arch. Gen. Psychiatry. 2010;67:94–101. doi: 10.1001/archgenpsychiatry.2009.170.
    1. Franz M.J., van Wormer J.J., Crain A.L., Boucher J.L., Histon T., Caplan W., Bowman J.D., Pronk N.P. Weight-loss outcomes: A systematic review and meta-analysis of weight-loss clinical trials with a minimum 1-year follow-up. J. Am. Diet. Assoc. 2007;107:1755–1767. doi: 10.1016/j.jada.2007.07.017.
    1. Moher D., Liberati A., Tetzlaff J., Altman D.G., The PRISMA Group Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. Ann. Intern. Med. 2009;151:264–269. doi: 10.7326/0003-4819-151-4-200908180-00135.
    1. American Psychiatric Association APA . Diagnostic and Statistical Manual of Mental Disorders. 4th ed. American Psychiatric Association; Washington, DC, USA: 2000.
    1. World Health Organization . The ICD-10 Classification of Mental and Behavioural Disorders: Clinical Descriptions and Diagnostic Guidelines. World Health Organization; Geneva, Switzerland: 1992.
    1. Reed G.M., First M.B., Medina-Mora M.E., Gureje O., Pike K.M., Saxena S. Draft diagnostic guidelines for ICD-11 mental and behavioural disorders available for review and comment. World Psychiatry. 2016 doi: 10.1002/wps.20322.
    1. Fairburn C.G., Cooper Z., O’Connor M. The Eating Disorder Examination. 17th ed. The Centre for Research on Eating Disorders; Oxford, UK: 2014. [(accessed on 7 December 2016)]. Available online: .
    1. Higgins J.P.T., Green S. Cochrane Handbook for Systematic Reviews of Interventions. The Cochrane Collaboration; Copenhagen, Denmark: 2011. [(accessed on 7 December 2016)]. Version 5.1.0. Available online: .
    1. Review Manager (RevMan) Copenhagen: The Nordic Cochrane Centre. The Cochrane Collaboration; Copenhagen, Denmark: 2014. Version 5.3.
    1. National Institute for Clinical Excellence (NICE) Eating Disorders—Core Interventions INTHE Treatment and Management of Anorexia Nervosa, Bulimia Nervosa and Related Eatingdisorders. National Institute for Clinical Excellence; London, UK: 2004. [(accessed on 23 December 2016)]. NICE Clinical Practice Guideline CG9. Available online: .
    1. Alfonsson S., Parling T., Ghaderi A. Group behavioral activation for patients with severe obesity and binge eating disorder: A randomized controlled trial. Behav. Modif. 2015;39:270–294. doi: 10.1177/0145445514553093.
    1. Gorin A.A., Le Grange D., Stone A.A. Effectiveness of spouse involvement in cognitive behavioral therapy for binge eating disorder. Int. J. Eat. Disord. 2003;33:421–433. doi: 10.1002/eat.10152.
    1. Grilo C.M., Masheb R.M. A randomized controlled comparison of guided self- help cognitive behavioral therapy and behavioral weight loss for binge eating disorder. Behav. Res. Ther. 2005;43:1509–1525. doi: 10.1016/j.brat.2004.11.010.
    1. Grilo C.M., Masheb R.M., Wilson G.T., Gueorguieva R., White M.A. Cognitive-behavioral therapy, behavioral weight loss, and sequential treatment for obese patients with binge-eating disorder: A randomized controlled trial. J. Consult Clin. Psychol. 2011;79:675–685. doi: 10.1037/a0025049.
    1. Grilo C.M., White M.A., Gueorguieva R., Barnes R.D., Masheb R.M. Self-help for binge eating disorder in primary care: A randomized controlled trial with ethnically and racially diverse obese patients. Behav. Res. Ther. 2013;51:855–861. doi: 10.1016/j.brat.2013.10.002.
    1. Kristeller J., Wolever R.Q., Sheets V. Mindfulness-based eating awareness training (MB-EAT) for binge eating: A randomized controlled trial. Mindfulness. 2014;5:282–297. doi: 10.1007/s12671-012-0179-1.
    1. Masheb R.M., Grilo C.M., Rolls B.J. A randomized controlled trial for obesity and binge eating disorder: Low-energy-density dietary counseling and cognitive behavioral therapy. Behav. Res. Ther. 2011;49:821–829. doi: 10.1016/j.brat.2011.09.006.
    1. Munsch S., Biedert E., Meyer A., Michael T., Schlup B., Tuch A., Margraf J. A randomized comparison of cognitive behavioral therapy and behavioral weight loss treatment for overweight individuals with binge eating disorder. Int. J. Eat. Disord. 2007;40:102–113. doi: 10.1002/eat.20350.
    1. Munsch S., Meyer A.H., Biedert E. Efficacy and predictors of long-term treatment success for Cognitive-Behavioral Treatment and Behavioral Weight-Loss-Treatment in overweight individuals with binge eating disorder. Behav. Res. Ther. 2012;50:775–785. doi: 10.1016/j.brat.2012.08.009.
    1. Ricca V., Castellini G., Mannucci E., Lo Sauro C., Ravaldi C., Rotella C.M., Faravelli C. Comparison of individual and group cognitive behavioral therapy for binge eating disorder. A randomized, three-year follow-up study. Appetite. 2010;55:656–665. doi: 10.1016/j.appet.2010.09.019.
    1. Shapiro J.R., Reba-Harrelson L., Dymek-Valentine M., Woolsom S.L., Hamer R.M., Bulik C.M. Feasibility and acceptability of CD-ROM-based cognitive- behavioural treatment for binge-eating disorder. Eur. Eat. Disord. Rev. 2007;15:175–184. doi: 10.1002/erv.787.
    1. Wilfley D.E., Welch R.R., Stein R.I., Spurrell E.B., Cohen L.R., Saelens B.E., Dounchis J.Z., Frank M.A., Wiseman C.V., Matt G.E. A randomized comparison of group cognitive-behavioral therapy and group interpersonal psychotherapy for the treatment of overweight individuals with binge-eating disorder. Arch. Gen. Psychiatry. 2002;59:713–721. doi: 10.1001/archpsyc.59.8.713.
    1. Agras W.S., Telch C.F., Arnow B., Eldredge K., Detzer M.J., Henderson J., Marnell M. Does interpersonal therapy help patients with binge eating disorder who fail to respond to cognitive-behavioral therapy? J. Consult Clin. Psychol. 1995;63:356–360. doi: 10.1037/0022-006X.63.3.356.
    1. Dingemans A.E., Spinhoven P., van Furth E.F. Predictors and mediators of treatment outcome in patients with binge eating disorder. Behav. Res. Ther. 2007;45:2551–2562. doi: 10.1016/j.brat.2007.06.003.
    1. Eldredge K.L., Agras W.S., Arnow B., Telch C.F., Bell S., Castonguay L., Marnell M. The effects of extending cognitive-behavioral therapy for binge eating disorder among initial treatment nonresponders. Int. J. Eat. Disord. 1997;21:347–352. doi: 10.1002/(SICI)1098-108X(1997)21:4<347::AID-EAT7>;2-O.
    1. Nauta H., Hospers H., Kok G., Jansen A. A comparison between a cognitive and a behavioral treatment for obese binge eaters and obese non-binge eaters. Behav. Ther. 2000;31:441–461. doi: 10.1016/S0005-7894(00)80024-6.
    1. Pendleton V.R., Goodrick G.K., Poston W.S.C., Reeves R.S., Foreyt J.P. Exercise augments the effects of cognitive-behavioral therapy in the treatment of binge eating. Int. J. Eat. Disord. 2002;31:172–184. doi: 10.1002/eat.10010.
    1. Safer D.L., Robinson A.H., Jo B. Outcome from a randomized controlled trial of group therapy for binge eating disorder: Comparing dialectical behavior therapy adapted for binge eating to an active comparison group therapy. Behav. Ther. 2010;41:106–120. doi: 10.1016/j.beth.2009.01.006.
    1. First M.B., Spitzer R.L., Gibbon M., Williams J.B.W. Structured Clinical Interviewfor DSM-IV Axis I Disorders-Patient Edition (SCID-I/P, Version 2.0) Biometric Research, New York State Psychiatric Institute; New York, NY, USA: 1996.
    1. Hay P., Chinn D., Forbes D., Madden S., Newton R., Sugenor L., Touyz S., Ward W., Royal Australian and New Zealand College of Psychiatrists Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the treatment of eating disorders. Aust. N. Z. J. Psychiatry. 2014;48:977–1008. doi: 10.1177/0004867414555814.
    1. Iacovino J.M., Gredysa D.M., Altman M., Wilfley D.E. Psychological treatments for binge eating disorder. Curr. Psychiatry Rep. 2012;14:432–446. doi: 10.1007/s11920-012-0277-8.
    1. Vancampfort D., Vanderlinden J., De Hert M., Adámkova M., Skjaerven L.H., Catalán-Matamoros D., Lundvik-Gyllensten A., Gómez-Conesa A., Ijntema R., Probst M. A systematic review on physical therapy interventions for patients with binge eating disorder. Disabil. Rehabil. 2013;35:2191–2196. doi: 10.3109/09638288.2013.771707.

Source: PubMed

スポンサーと協力者

医学的状態

薬物療法

3
購読する