Senior Associate Scientist
Charles River Laboratories International Inc (CRL)
Mattawan, MI, US, 49071
Senior Associate Scientist Req ID #: 186458 Location:
Mattawan, MI, US, 49071 For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.
IMPORTANT: In order to be considered for this position, a resume/CV must be uploaded and submitted during the application process. Please make sure work history and education are added correctly. Job Summary We are seeking an experienced Senior Associate Scientist for our Immunology team located in Mattawan, MI.
The Immunology and Immunochemistry disciplines support large molecule drug development using ligand binding assays (LBA), such as enzyme-linked immunosorbent assay (ELISA), to measure large molecules and their immune responses. The main types of assays include Pharmacokinetic (PK) assays to measure drug and Immunogenicity assay to measure anti-drug antibodies (ADA) and neutralizing antibodies (NAb). Other assay types also performed are branched DNA (bDNA) and cell-based assays. An array of platforms are used to support these assays that include spectrophotometer, Meso Scale Discovery (MSD), Luminex and Gyrolab. Utilizing these platforms/assays, the teams are responsible for the method development, validation and routine sample analysis in both the regulated and non-regulated space of non-clinical and clinical studies.
Essential Functions (The fundamental Competencies/Skills& Responsibilities of the role (products and services provided/results accomplished) include, but are not limited to, those listed: Efficiently perform and document all procedures, materials and results in compliance with applicable regulatory standards as applicable (protocols, methods, SOPs, etc.) Assist with the completion of laboratory investigations, assay troubleshooting, quality observations, and problem solving of technical and/or regulatory issues with oversight Effectively develop and validate quantitative/qualitative methods/procedures with limited complexity/scope in one operational area with minimal oversight Perform data analysis in appropriate software for at least one analytical platform with minimal oversight Operate laboratory instruments including their respective software applications for 1-2 analytical platforms with minimal oversight Develop critical thinking, troubleshooting and time management skills aligned with needs of operational areas Demonstrate effective communication skills through informal discussions with peers, supervisor, and team Develop ability to recognize method and/or data issues and communicate them to management to minimize study impact with minimal oversight Develop knowledge of regulatory and GXP requirements, industry standards and company SOPs within one operational area Performs all other related duties as assigned Job Qualifications
The following are minimum requirements related to the Senior Associate Scientist position. Bachelor's degree (BA/BS) with 5-7 years of relevant working experience. Master's degree (MS) with 1-2 years of relevant work experience. Doctorate degree (PhD) with no experience. An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above. Ability to communicate verbally and in writing at all levels inside and outside the organization. Basic familiarity with Microsoft Office Suite. Computer skills, commensurate with Essential Functions, including the ability to learn a validated system. Ability to work extended hours beyond normal work schedule to include, but not limited to evenings, weekends, extended shifts, and/or extra shifts; sometimes on short notice. Ability to work under specific time constraints.
IMPORTANT: A resume is required to be considered for this position. If you have not uploaded your resume in your candidate profile, please return to upload field and attach your resume/CV.
Charles River is a U.S. Federal Contractor. As a result, we must follow the Presidential Executive Order to mandate vaccinations, and ensure our employees are fully vaccinated against COVID-19. Our main priority is the wellbeing, health, and safety of our people. We require proof of vaccination from all employees.
Anyone with requests for disability-related and/or religious exemptions should contact Talent Acquisition ([email protected]) so that information can be provided about the accommodation process at Charles River.
About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.
About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.
Equal Employment Opportunity
Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to [email protected] This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.
For more information, please visit www.criver.com.
Nearest Major Market: Kalamazoo
Job Segment: Research Scientist, Senior Scientist, Laboratory, Pharmaceutical, Recruiting, Science, Human Resources
Similar CRA jobs
Scientist, Antibody Discovery and Engineering
FSP Clinical Research Associate / FSP 臨床開発モニター（東京・大阪・神戸）
Clinical Team Manager/Senior Clinical Team Manager
Senior Lead Clinical Data Manager (Home/Office-Based) - IQVIA Biotech
Research Associate - Cellular and Molecular Biology ** $1000 Sign on Bonus
Associate Study Start-Up Manager - (UK/EU Homebased) - IQVIA Biotech
Associate Data Science Director
Senior Consultant, Health Economics Modelling
Clinical Research Associate II （FSP）
Associate Benefit-Risk Management Director (Open to ALL UK & EU)
Senior Resource Planner - Home Based
Associate/ Operations Finance Analyst, Cambridge UK
Associate Project Manager - Labs (Small Molecule)
Clinical Research Associate II - office-based / in-house
Training Associate - Immunology/Immunochemistry and Biomarkers
Senior Affairs Associate (Clinical writer)
Experienced Clinical Research Associate (CRA II, Senior CRA, Principal CRA) - Home Based in Florida
Senior Feasibility and Strategy Leader (Clinical Trials) - Home Based
Sr Clinical Research Associate, Oncology (Mid West) - IQVIA Biotech