Fatigue and QoL Among Gastric Cancer Patients Undergoing Abdominal Surgery
A Survey of Fatigue and QoL Among Gastric Cancer Patients Undergoing Major Abdominal Surgery
Background: Cancer-related fatigue (CRF), one of the indicators of QoL, is one of the most common side effects of cancer and its treatment. However, the pathophysiological mechanisms involved in CRF among cancer patients are not completely understood. Therefore, more in-depth researches on CRF of surgical patients suffering from gastric cancer are needed in Taiwan.
Purpose: The purpose of this study is to examine the incidence rate and correlated factors (QoL and immune biomarkers) of CRF among gastric cancer patients undergoing major abdominal surgery.
Method: A longitudinal study was conducted to recruit gastric cancer patients who scheduled to operate at surgical clinics from a northern medical center in Taiwan. The data will be collected with a structured questionnaire and Immune markers assessments via purposive sampling of 120 subjects. Before operation, on day 1 after operation, and on day 7 after operation, the biomarkers will be measured. The BFI-T questionnaire will be filled out before surgery and on day 1, 2, 7, 28 after surgery; The EORTC QLQ-C30 and EORTC QLQ-STO22 questionnaire will be filled out before surgery and on day 7, 28 after surgery; Type D scale-14(Taiwanese version) questionnaire will be filled out before surgery and on day 28 after surgery. Data will be analyzed by using descriptive statistics, paired t-test, Chi square test, Pearson's correlation, and the generalized estimating equation (GEE) was used to identify significant factors with QoL after operation.
Anticipated achievement: The anticipated achievement of this study is to provide healthcare providers with more knowledge about CRF, and help them to enhance the quality of life on gastric cancer patients in the future.
연구 개요
연구 유형
등록 (예상)
연락처 및 위치
연구 장소
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Taipei, 대만, 100
- 모병
- National Taiwan University Hospital
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연락하다:
- Hui-Ting Yang, MSN
- 전화번호: +886930005267
- 이메일: sophy790303@gmail.com
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수석 연구원:
- Jin-Ming Wu, PhD
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부수사관:
- Shiow-Ching Shun, PhD
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참여기준
자격 기준
공부할 수 있는 나이
건강한 자원 봉사자를 받아들입니다
연구 대상 성별
샘플링 방법
연구 인구
설명
Inclusion Criteria:
- Clinical diagnosis of gastric cancer and schedule for major abdominal surgery
- Eastern Cooperative Oncology Group (ECOG) performance status ≤2
Exclusion Criteria:
- Severe multiple organ impairment, comorbidities or immune disorder before surgery
- Undergoing chemotherapy or radiotherapy
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Fatigue
기간: Change from baseline fatigue at 1 month
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Brief Fatigue Inventory-Taiwan Form (BFI-T).
The questionnaire includes 10 items to assess fatigue.
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Change from baseline fatigue at 1 month
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2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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Quality of Life
기간: Change from baseline quality of life at 1 month
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Quality of Life Questionnaire(EORTC QLQ-C30 and EORTC QLQ-STO22 questionnaire).
The questionnaire includes 52 items to assess quality of life.
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Change from baseline quality of life at 1 month
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공동 작업자 및 조사자
수사관
- 수석 연구원: Jin-Ming Wu, PhD, National Taiwan University Hospital
연구 기록 날짜
연구 주요 날짜
연구 시작 (실제)
기본 완료 (예상)
연구 완료 (예상)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .