Grape Seed Powder and Vitamin C Supplementation for Liver Disease (Acquired Hepatic Jaundice) (AHJ)
Impact of Grape (VITIS VINIFERA) Seed Powder Along With Vitamin C Supplementation on Serum Bilirubin Levels in Patients With Acquired Hepatic Jaundice
연구 개요
상세 설명
According to my study, the division of patients was done between two groups: one was named as Conventional group (CG) and other was named as Intervention group (IG). The conventional treatment group received only conventional medication and intervention group was given Grape-C capsule with dose of one tablet per day for 4 weeks after lunch along with conventional medication. Grape-C capsule continued for 4 weeks and the data was obtained at the initiation and at end of intervention (after 4th week).
According to my research study results the intervention group had a significant decrease in bilirubin levels, ALT, AST, ALP and increase the albumin and gamma glutamyl transferase (GGT) compared to the conventional group. The p-values for the comparison between pre and post intervention levels were highly significant rather than the conventional groups indicating a statistically significant difference.
연구 유형
등록 (실제)
단계
- 해당 없음
연락처 및 위치
연구 장소
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Punjab Province
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Lahore, Punjab Province, 파키스탄
- University of Lahore
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참여기준
자격 기준
공부할 수 있는 나이
- 성인
건강한 자원 봉사자를 받아들입니다
설명
Inclusion Criteria:
- Both men and women
- Participants between the ages of 20-40 years will be included
- Patients having signs and symptoms of acquired hepatic jaundice
- Patients having high serum bilirubin, albumin, ALT, AST, ALP levels
- The patient having ALT level more than 10-50 U/L were included
- The participants having AST level above than 0-40 IU/L were included in this study
- Patients having ALP level more than 30 - 130 U/L were included in this research study
- Patients having level of bilirubin above than 0 - 21 μmol/L were included in this investigation
- Participants having the range of albumin more than 30-50 g/L were included in this research
- Participants those were underweighted were included
Exclusion Criteria:
- Patients who already taking any supplement or medication
- Participants taking any anti-inflammatory medications
- People who were suffering from any other disease
- Patients who have any known allergies
- Non willing patients
- Lactating women
- Pregnant women
- Smokers
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 치료
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
|---|---|
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간섭 없음: Conventional group
Control group
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실험적: Intervention group
Targeted group with intervention
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Grape-C supplement purchased from Nutrifactor brand.
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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Bilirubin levels
기간: 4 weeks
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In this study results showed the significant decrease in bilirubin levels in interventional group as compared to the conventional group
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4 weeks
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공동 작업자 및 조사자
수사관
- 연구 의자: Dr Habib-ur-Rehman Rehman, PhD Food and Nutrition, University of Lahore
간행물 및 유용한 링크
일반 간행물
- DOI: 10.4103/1319-3767.65197
유용한 링크
- Ghaffar, S., Naqvi, M. A., Fayyaz, A., Abid, M. K., Khayitov, K. N., Jalil, A. T., Alsaikhan, F., Hammid, A. T., Al-Gazally, M. E., & Mohammadparast, V. (2022). What is the influence of grape products on liver enzymes? A systematic review and meta-ana
- Adikwu, E., & Deo, O. (2013). Hepatoprotective effect of vitamin C (ascorbic acid)
연구 기록 날짜
연구 주요 날짜
연구 시작 (실제)
기본 완료 (실제)
연구 완료 (실제)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 연구와 관련된 용어
기타 연구 ID 번호
- AZ786
- University of Lahore (기타 식별자: Self)
개별 참가자 데이터(IPD) 계획
개별 참가자 데이터(IPD)를 공유할 계획입니까?
약물 및 장치 정보, 연구 문서
미국 FDA 규제 의약품 연구
미국 FDA 규제 기기 제품 연구
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