Grape Seed Powder and Vitamin C Supplementation for Liver Disease (Acquired Hepatic Jaundice) (AHJ)
Impact of Grape (VITIS VINIFERA) Seed Powder Along With Vitamin C Supplementation on Serum Bilirubin Levels in Patients With Acquired Hepatic Jaundice
研究概览
详细说明
According to my study, the division of patients was done between two groups: one was named as Conventional group (CG) and other was named as Intervention group (IG). The conventional treatment group received only conventional medication and intervention group was given Grape-C capsule with dose of one tablet per day for 4 weeks after lunch along with conventional medication. Grape-C capsule continued for 4 weeks and the data was obtained at the initiation and at end of intervention (after 4th week).
According to my research study results the intervention group had a significant decrease in bilirubin levels, ALT, AST, ALP and increase the albumin and gamma glutamyl transferase (GGT) compared to the conventional group. The p-values for the comparison between pre and post intervention levels were highly significant rather than the conventional groups indicating a statistically significant difference.
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
-
-
Punjab Province
-
Lahore、Punjab Province、巴基斯坦
- University of Lahore
-
-
参与标准
资格标准
适合学习的年龄
- 成人
接受健康志愿者
描述
Inclusion Criteria:
- Both men and women
- Participants between the ages of 20-40 years will be included
- Patients having signs and symptoms of acquired hepatic jaundice
- Patients having high serum bilirubin, albumin, ALT, AST, ALP levels
- The patient having ALT level more than 10-50 U/L were included
- The participants having AST level above than 0-40 IU/L were included in this study
- Patients having ALP level more than 30 - 130 U/L were included in this research study
- Patients having level of bilirubin above than 0 - 21 μmol/L were included in this investigation
- Participants having the range of albumin more than 30-50 g/L were included in this research
- Participants those were underweighted were included
Exclusion Criteria:
- Patients who already taking any supplement or medication
- Participants taking any anti-inflammatory medications
- People who were suffering from any other disease
- Patients who have any known allergies
- Non willing patients
- Lactating women
- Pregnant women
- Smokers
学习计划
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
无干预：Conventional group
Control group
|
|
|
实验性的：Intervention group
Targeted group with intervention
|
Grape-C supplement purchased from Nutrifactor brand.
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Bilirubin levels
大体时间：4 weeks
|
In this study results showed the significant decrease in bilirubin levels in interventional group as compared to the conventional group
|
4 weeks
|
合作者和调查者
调查人员
- 学习椅：Dr Habib-ur-Rehman Rehman, PhD Food and Nutrition、University of Lahore
出版物和有用的链接
一般刊物
- DOI: 10.4103/1319-3767.65197
有用的网址
- Ghaffar, S., Naqvi, M. A., Fayyaz, A., Abid, M. K., Khayitov, K. N., Jalil, A. T., Alsaikhan, F., Hammid, A. T., Al-Gazally, M. E., & Mohammadparast, V. (2022). What is the influence of grape products on liver enzymes? A systematic review and meta-ana
- Adikwu, E., & Deo, O. (2013). Hepatoprotective effect of vitamin C (ascorbic acid)
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他研究编号
- AZ786
- University of Lahore (其他标识符：Self)
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
药物和器械信息、研究文件
研究美国 FDA 监管的药品
研究美国 FDA 监管的设备产品
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